from the Kanehisa laboratories with thanks: Figures are subject to KEGG copyright conditions. Pathway Search Result : Click on "show all objects" for legends under figures .

Enhanced links to genes are provided by Yellow proteins are part of the Huntingtin (HTT) interactome Interactions from Entrez gene

Pathway Search Result

Following object(s) was/were not found ATXN2 BANF1 C10orf116 C15orf63 CXorf27 CHD3 CRMP1 DNAJB4 EIF2C2 FEZ1 FICD F8A1 GPRASP2 GRAP GSX2 HSPB8 KIAA1377 MED31 MTSS1 NCOR1 OPTN PACSIN1 RASD2 SAP30 SLC25A19 ZDHHC17 ZNF395

CASP2 -----> apoptosis: MAP3K10 ------> MAPK : MAGEA3 ------> Melanoma: PDK2 --------> glycolysis IKBKAP --> B cell signalling HIP1R -----> Huntington's disease

hsa05016 Huntington's disease - Homo sapiens (human) (17)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:161 AP2A2, ADTAB, CLAPA2, HIP9, HYPJ; adaptor-related protein complex 2, alpha 2 subunit; K11824 AP-2 complex subunit alpha
hsa:1742 DLG4, FLJ97752, FLJ98574, PSD95, SAP-90, SAP90; discs, large homolog 4 (Drosophila); K11828 discs large protein 4
hsa:25942 SIN3A, DKFZp434K2235, FLJ90319, KIAA0700; SIN3 homolog A, transcription regulator (yeast); K11644 paired amphipathic helix protein Sin3a
hsa:3064 HTT, HD, IT15; huntingtin; K04533 huntingtin
hsa:3092 HIP1, ILWEQ, MGC126506; huntingtin interacting protein 1; K04559 huntingtin interacting protein 1
hsa:55081 IFT57, ESRRBL1, FLJ10147, HIPPI, MHS4R2; intraflagellar transport 57 homolog (Chlamydomonas); K04638 estrogen-related receptor beta like 1
hsa:5978 REST, NRSF, XBR; RE1-silencing transcription factor; K09222 RE1-silencing transcription factor
hsa:6667 SP1; Sp1 transcription factor; K04684 transcription factor Sp1
hsa:6874 TAF4, FLJ41943, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; K03129 transcription initiation factor TFIID subunit 4
hsa:6908 TBP, GTF2D, GTF2D1, HDL4, MGC117320, MGC126054, MGC126055, SCA17, TFIID; TATA box binding protein; K03120 transcription initiation factor TFIID TATA-box-binding protein
hsa:7052 TGM2, G-ALPHA-h, GNAH, TG2, TGC; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (EC:2.3.2.13); K05625 transglutaminase 2 [EC:2.3.2.13]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]
hsa:9001 HAP1, HAP2, HIP5, HLP, hHLP1; huntingtin-associated protein 1; K04647 huntingtin-associated protein 1

hsa05200 Pathways in cancer - Homo sapiens (human) (10)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:1487 CTBP1, BARS, MGC104684; C-terminal binding protein 1; K04496 C-terminal binding protein
hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:51588 PIAS4, FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K04706 protein inhibitor of activated STAT
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:7175 TPR; translocated promoter region (to activated MET oncogene); K09291 nucleoprotein TPR
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa04010 MAPK signaling pathway - Homo sapiens (human) (7)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:5921 RASA1, CM-AVM, CMAVM, DKFZp434N071, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP; RAS p21 protein activator (GTPase activating protein) 1; K04352 Ras GTPase-activating protein 1
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa05010 Alzheimer's disease - Homo sapiens (human) (6)



hsa:2597 GAPDH, G3PD, GAPD, MGC88685; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12); K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:840 CASP7, CMH-1, ICE-LAP3, MCH3; caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60); K04397 caspase 7 [EC:3.4.22.60]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa05215 Prostate cancer - Homo sapiens (human) (6)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04210 Apoptosis - Homo sapiens (human) (6)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:839 CASP6, MCH2; caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59); K04396 caspase 6 [EC:3.4.22.59]
hsa:840 CASP7, CMH-1, ICE-LAP3, MCH3; caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60); K04397 caspase 7 [EC:3.4.22.60]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa04144 Endocytosis - Homo sapiens (human) (6)



hsa:161 AP2A2, ADTAB, CLAPA2, HIP9, HYPJ; adaptor-related protein complex 2, alpha 2 subunit; K11824 AP-2 complex subunit alpha
hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:28964 GIT1; G protein-coupled receptor kinase interacting ArfGAP 1; K05737 G protein-coupled receptor kinase interactor 1
hsa:51100 SH3GLB1, Bif-1, KIAA0491, dJ612B15.2; SH3-domain GRB2-like endophilin B1; K11248 endophilin-B
hsa:6457 SH3GL3, CNSA3, EEN-2B-L3, EEN-B2, HsT19371, SH3D2C, SH3P13; SH3-domain GRB2-like 3; K11247 endophilin-A
hsa:857 CAV1, BSCL3, CGL3, MSTP085, VIP21; caveolin 1, caveolae protein, 22kDa; K06278 caveolin 1

hsa05160 Hepatitis C - Homo sapiens (human) (6)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:51588 PIAS4, FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K04706 protein inhibitor of activated STAT
hsa:5610 EIF2AK2, EIF2AK1, MGC126524, PKR, PRKR; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1); K08860 eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human) (5)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:28964 GIT1; G protein-coupled receptor kinase interacting ArfGAP 1; K05737 G protein-coupled receptor kinase interactor 1
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:5217 PFN2, D3S1319E, PFL; profilin 2; K05759 profilin
hsa:9459 ARHGEF6, COOL2, Cool-2, KIAA0006, MRX46, PIXA, alpha-PIX, alphaPIX; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; K05729 Rho guanine nucleotide exchange factor 6

hsa05214 Glioma - Homo sapiens (human) (5)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04510 Focal adhesion - Homo sapiens (human) (5)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:857 CAV1, BSCL3, CGL3, MSTP085, VIP21; caveolin 1, caveolae protein, 22kDa; K06278 caveolin 1

hsa01100 Metabolic pathways - Homo sapiens (human) (5)

hsa:1373 CPS1, CPSASE1; carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16); K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
hsa:2597 GAPDH, G3PD, GAPD, MGC88685; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12); K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
hsa:26330 GAPDHS, GAPD2, GAPDH-2, GAPDS, HSD-35; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (EC:1.2.1.12); K10705 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12]
hsa:64768 IPPK, C9orf12, FLJ13163, INSP5K2, IP5K, IPK1, KIAA0699, bA476B13.1; inositol 1,3,4,5,6-pentakisphosphate 2-kinase (EC:2.7.1.158); K10572 inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
hsa:875 CBS, HIP4; cystathionine-beta-synthase (EC:4.2.1.22); K01697 cystathionine beta-synthase [EC:4.2.1.22]

hsa04912 GnRH signaling pathway - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04910 Insulin signaling pathway - Homo sapiens (human) (4)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin
hsa:9322 TRIP10, CIP4, HSTP, STOT, STP; thyroid hormone receptor interactor 10; K07196 thyroid hormone receptor interactor 10

hsa04540 Gap junction - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:203068 TUBB, M40, MGC117247, MGC16435, OK/SW-cl.56, TUBB1, TUBB5; tubulin, beta; K07375 tubulin beta
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3

hsa05223 Non-small cell lung cancer - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:28964 GIT1; G protein-coupled receptor kinase interacting ArfGAP 1; K05737 G protein-coupled receptor kinase interactor 1
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa04012 ErbB signaling pathway - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]

hsa03040 Spliceosome - Homo sapiens (human) (4)



hsa:10915 TCERG1, CA150, MGC133200, TAF2S, Urn1; transcription elongation regulator 1; K12824 transcription elongation regulator 1
hsa:1655 DDX5, DKFZp434E109, DKFZp686J01190, G17P1, HLR1, HUMP68, p68; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (EC:3.6.4.13); K12823 ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
hsa:25766 PRPF40B, HYPC; PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); K12821 pre-mRNA-processing factor 40
hsa:55660 PRPF40A, FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); K12821 pre-mRNA-processing factor 40

hsa04630 Jak-STAT signaling pathway - Homo sapiens (human) (4)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:51588 PIAS4, FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K04706 protein inhibitor of activated STAT

hsa05211 Renal cell carcinoma - Homo sapiens (human) (4)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]

hsa05220 Chronic myeloid leukemia - Homo sapiens (human) (4)



hsa:1487 CTBP1, BARS, MGC104684; C-terminal binding protein 1; K04496 C-terminal binding protein
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa05212 Pancreatic cancer - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:9459 ARHGEF6, COOL2, Cool-2, KIAA0006, MRX46, PIXA, alpha-PIX, alphaPIX; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; K05729 Rho guanine nucleotide exchange factor 6

hsa05213 Endometrial cancer - Homo sapiens (human) (4)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04722 Neurotrophin signaling pathway - Homo sapiens (human) (4)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04062 Chemokine signaling pathway - Homo sapiens (human) (3)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]

hsa05145 Toxoplasmosis - Homo sapiens (human) (3)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa05222 Small cell lung cancer - Homo sapiens (human) (3)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:51588 PIAS4, FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K04706 protein inhibitor of activated STAT
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human) (3)



hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:64768 IPPK, C9orf12, FLJ13163, INSP5K2, IP5K, IPK1, KIAA0699, bA476B13.1; inositol 1,3,4,5,6-pentakisphosphate 2-kinase (EC:2.7.1.158); K10572 inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa05210 Colorectal cancer - Homo sapiens (human) (3)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa04310 Wnt signaling pathway - Homo sapiens (human) (3)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:1487 CTBP1, BARS, MGC104684; C-terminal binding protein 1; K04496 C-terminal binding protein
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04380 Osteoclast differentiation - Homo sapiens (human) (3)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2

hsa05416 Viral myocarditis - Homo sapiens (human) (3)



hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]
hsa:857 CAV1, BSCL3, CGL3, MSTP085, VIP21; caveolin 1, caveolae protein, 22kDa; K06278 caveolin 1

hsa04660 T cell receptor signaling pathway - Homo sapiens (human) (3)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]

hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human) (3)



hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:834 CASP1, ICE, IL1BC, P45; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (EC:3.4.22.36); K01370 caspase 1 [EC:3.4.22.36]
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human) (3)



hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa05218 Melanoma - Homo sapiens (human) (3)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04330 Notch signaling pathway - Homo sapiens (human) (3)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:1487 CTBP1, BARS, MGC104684; C-terminal binding protein 1; K04496 C-terminal binding protein
hsa:8850 KAT2B, CAF, P, P/CAF, PCAF; K(lysine) acetyltransferase 2B (EC:2.3.1.48); K06062 histone acetyltransferase [EC:2.3.1.48]

hsa04720 Long-term potentiation - Homo sapiens (human) (3)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04020 Calcium signaling pathway - Homo sapiens (human) (3)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04916 Melanogenesis - Homo sapiens (human) (3)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04115 p53 signaling pathway - Homo sapiens (human) (3)



hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human) (2)



hsa:834 CASP1, ICE, IL1BC, P45; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (EC:3.4.22.36); K01370 caspase 1 [EC:3.4.22.36]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa05219 Bladder cancer - Homo sapiens (human) (2)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human) (2)



hsa:2597 GAPDH, G3PD, GAPD, MGC88685; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12); K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
hsa:26330 GAPDHS, GAPD2, GAPDH-2, GAPDS, HSD-35; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (EC:1.2.1.12); K10705 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12]

hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human) (2)



hsa:3093 UBE2K, DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (EC:6.3.2.19); K04649 ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19]
hsa:51588 PIAS4, FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K04706 protein inhibitor of activated STAT

hsa04530 Tight junction - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:8189 SYMPK, FLJ27092, SPK, SYM; symplekin; K06100 symplekin

hsa05221 Acute myeloid leukemia - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2

hsa04970 Salivary secretion - Homo sapiens (human) (2)



hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human) (2)



hsa:3300 DNAJB2, HSJ1, HSPF3; DnaJ (Hsp40) homolog, subfamily B, member 2; K09508 DnaJ homolog subfamily B member 2
hsa:5610 EIF2AK2, EIF2AK1, MGC126524, PKR, PRKR; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1); K08860 eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1]

hsa04662 B cell receptor signaling pathway - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2

hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2

hsa04114 Oocyte meiosis - Homo sapiens (human) (2)



hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human) (2)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:1780 DYNC1I1, DNCI1, DNCIC1; dynein, cytoplasmic 1, intermediate chain 1; K10415 dynein intermediate chain, cytosolic

hsa04350 TGF-beta signaling pathway - Homo sapiens (human) (2)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:6667 SP1; Sp1 transcription factor; K04684 transcription factor Sp1

hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa04971 Gastric acid secretion - Homo sapiens (human) (2)



hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04110 Cell cycle - Homo sapiens (human) (2)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]

hsa04145 Phagosome - Homo sapiens (human) (2)



hsa:1780 DYNC1I1, DNCI1, DNCIC1; dynein, cytoplasmic 1, intermediate chain 1; K10415 dynein intermediate chain, cytosolic
hsa:203068 TUBB, M40, MGC117247, MGC16435, OK/SW-cl.56, TUBB1, TUBB5; tubulin, beta; K07375 tubulin beta

hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human) (2)



hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]
hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa03013 RNA transport - Homo sapiens (human) (2)



hsa:7175 TPR; translocated promoter region (to activated MET oncogene); K09291 nucleoprotein TPR
hsa:7341 SUMO1, DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); K12160 small ubiquitin-related modifier

hsa04270 Vascular smooth muscle contraction - Homo sapiens (human) (2)



hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3
hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04612 Antigen processing and presentation - Homo sapiens (human) (2)



hsa:1385 CREB1, CREB, MGC9284; cAMP responsive element binding protein 1; K05870 cAMP response element-binding protein 1
hsa:3308 HSPA4, APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY; heat shock 70kDa protein 4; K09489 heat shock 70kDa protein 4

hsa04360 Axon guidance - Homo sapiens (human) (2)



hsa:5058 PAK1, MGC130000, MGC130001, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1]
hsa:5921 RASA1, CM-AVM, CMAVM, DKFZp434N071, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP; RAS p21 protein activator (GTPase activating protein) 1; K04352 Ras GTPase-activating protein 1

hsa04320 Dorso-ventral axis formation - Homo sapiens (human) (2)



hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]
hsa:2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2

hsa05216 Thyroid cancer - Homo sapiens (human) (2)



hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53
hsa:7175 TPR; translocated promoter region (to activated MET oncogene); K09291 nucleoprotein TPR

hsa03022 Basal transcription factors - Homo sapiens (human) (2)



hsa:6874 TAF4, FLJ41943, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; K03129 transcription initiation factor TFIID subunit 4
hsa:6908 TBP, GTF2D, GTF2D1, HDL4, MGC117320, MGC126054, MGC126055, SCA17, TFIID; TATA box binding protein; K03120 transcription initiation factor TFIID TATA-box-binding protein

hsa04520 Adherens junction - Homo sapiens (human) (2)



hsa:1387 CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48]
hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]

hsa04150 mTOR signaling pathway - Homo sapiens (human) (1)

hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]

hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human) (1)

hsa:1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1]

hsa03450 Non-homologous end-joining - Homo sapiens (human) (1)

hsa:2547 XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6; K10884 ATP-dependent DNA helicase 2 subunit 1

hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human) (1)

hsa:10813 UTP14A, FLJ37089, KIAA0266, NYCO16, SDCCAG16, dJ537K23.3; UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast); K14567 U3 small nucleolar RNA-associated protein 14

hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human) (1)

hsa:2358 FPR2, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R; formyl peptide receptor 2; K04173 formyl peptide receptor-like

hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human) (1)

hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]

hsa04370 VEGF signaling pathway - Homo sapiens (human) (1)

hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]

hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human) (1)

hsa:203068 TUBB, M40, MGC117247, MGC16435, OK/SW-cl.56, TUBB1, TUBB5; tubulin, beta; K07375 tubulin beta

hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human) (1)

hsa:857 CAV1, BSCL3, CGL3, MSTP085, VIP21; caveolin 1, caveolae protein, 22kDa; K06278 caveolin 1

hsa04740 Olfactory transduction - Homo sapiens (human) (1)

hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human) (1)

hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]

hsa04742 Taste transduction - Homo sapiens (human) (1)

hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3

hsa00620 Pyruvate metabolism - Homo sapiens (human) (1)

hsa:3029 HAGH, GLO2, GLX2, GLXII, HAGH1; hydroxyacylglutathione hydrolase (EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]

hsa00562 Inositol phosphate metabolism - Homo sapiens (human) (1)

hsa:64768 IPPK, C9orf12, FLJ13163, INSP5K2, IP5K, IPK1, KIAA0699, bA476B13.1; inositol 1,3,4,5,6-pentakisphosphate 2-kinase (EC:2.7.1.158); K10572 inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]

hsa04972 Pancreatic secretion - Homo sapiens (human) (1)

hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3

hsa00910 Nitrogen metabolism - Homo sapiens (human) (1)

hsa:1373 CPS1, CPSASE1; carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16); K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]

hsa03015 mRNA surveillance pathway - Homo sapiens (human) (1)

hsa:8189 SYMPK, FLJ27092, SPK, SYM; symplekin; K06100 symplekin

hsa04744 Phototransduction - Homo sapiens (human) (1)

hsa:801 CALM1, CALM2, CALM3, CALML2, CAMI, DD132, PHKD; calmodulin 1 (phosphorylase kinase, delta) (EC:2.7.11.19); K02183 calmodulin

hsa04730 Long-term depression - Homo sapiens (human) (1)

hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3

hsa00330 Arginine and proline metabolism - Homo sapiens (human) (1)

hsa:1373 CPS1, CPSASE1; carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16); K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]

hsa00310 Lysine degradation - Homo sapiens (human) (1)

hsa:29072 SETD2, FLJ16420, FLJ22472, FLJ23184, FLJ45883, FLJ46217, HBP231, HIF-1, HYPB, KIAA1732, KMT3A, SET2, p231HBP; SET domain containing 2 (EC:2.1.1.43); K11423 histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43]

hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human) (1)

hsa:841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473; caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61); K04398 caspase 8 [EC:3.4.22.61]

hsa05012 Parkinson's disease - Homo sapiens (human) (1)

hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa03320 PPAR signaling pathway - Homo sapiens (human) (1)

hsa:7316 UBC, HMG20; ubiquitin C; K08770 ubiquitin C

hsa05217 Basal cell carcinoma - Homo sapiens (human) (1)

hsa:7157 TP53, FLJ92943, LFS1, P53, TRP53; tumor protein p53; K04451 tumor protein p53

hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human) (1)

hsa:834 CASP1, ICE, IL1BC, P45; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (EC:3.4.22.36); K01370 caspase 1 [EC:3.4.22.36]

hsa04950 Maturity onset diabetes of the young - Homo sapiens (human) (1)

hsa:4760 NEUROD1, BETA2, BHF-1, MODY6, NEUROD, bHLHa3; neurogenic differentiation 1; K08033 neurogenic differentiation factor 1

hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human) (1)

hsa:875 CBS, HIP4; cystathionine-beta-synthase (EC:4.2.1.22); K01697 cystathionine beta-synthase [EC:4.2.1.22]

hsa05131 Shigellosis - Homo sapiens (human) (1)

hsa:5217 PFN2, D3S1319E, PFL; profilin 2; K05759 profilin

hsa05150 Staphylococcus aureus infection - Homo sapiens (human) (1)

hsa:2358 FPR2, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R; formyl peptide receptor 2; K04173 formyl peptide receptor-like

hsa00270 Cysteine and methionine metabolism - Homo sapiens (human) (1)

hsa:875 CBS, HIP4; cystathionine-beta-synthase (EC:4.2.1.22); K01697 cystathionine beta-synthase [EC:4.2.1.22]

hsa04920 Adipocytokine signaling pathway - Homo sapiens (human) (1)

hsa:207 AKT1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA; v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1); K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1]

hsa05146 Amoebiasis - Homo sapiens (human) (1)

hsa:836 CASP3, CPP32, CPP32B, SCA-1; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56); K02187 caspase 3 [EC:3.4.22.56]

hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human) (1)

hsa:1373 CPS1, CPSASE1; carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16); K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]