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hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human) (95)

hsa:57007 ACKR3; atypical chemokine receptor 3 hsa:650 BMP2; bone morphogenetic protein 2 hsa:6346 CCL1; C-C motif chemokine ligand 1 hsa:6356 CCL11; C-C motif chemokine ligand 11 hsa:6357 CCL13; C-C motif chemokine ligand 13 hsa:6362 CCL18; C-C motif chemokine ligand 18 hsa:6363 CCL19; C-C motif chemokine ligand 19 hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6364 CCL20; C-C motif chemokine ligand 20 hsa:6366 CCL21; C-C motif chemokine ligand 21 hsa:6367 CCL22; C-C motif chemokine ligand 22 hsa:6369 CCL24; C-C motif chemokine ligand 24 hsa:10344 CCL26; C-C motif chemokine ligand 26 hsa:56477 CCL28; C-C motif chemokine ligand 28 hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:6354 CCL7; C-C motif chemokine ligand 7 hsa:6355 CCL8; C-C motif chemokine ligand 8 hsa:1230 CCR1; C-C motif chemokine receptor 1 hsa:729230 CCR2; C-C motif chemokine receptor 2 hsa:1234 CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) hsa:1236 CCR7; C-C motif chemokine receptor 7 hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:970 CD70; CD70 molecule hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1437 CSF2; colony stimulating factor 2 hsa:1438 CSF2RA; colony stimulating factor 2 receptor alpha subunit hsa:1440 CSF3; colony stimulating factor 3 hsa:6376 CX3CL1; C-X3-C motif chemokine ligand 1 hsa:1524 CX3CR1; C-X3-C motif chemokine receptor 1 hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:6373 CXCL11; C-X-C motif chemokine ligand 11 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:10563 CXCL13; C-X-C motif chemokine ligand 13 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:2921 CXCL3; C-X-C motif chemokine ligand 3 hsa:6374 CXCL5; C-X-C motif chemokine ligand 5 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:4283 CXCL9; C-X-C motif chemokine ligand 9 hsa:3579 CXCR2; C-X-C motif chemokine receptor 2 hsa:2833 CXCR3; C-X-C motif chemokine receptor 3 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:643 CXCR5; C-X-C motif chemokine receptor 5 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2324 FLT4; fms related tyrosine kinase 4 (EC:2.7.10.1) hsa:3082 HGF; hepatocyte growth factor hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3596 IL13; interleukin 13 hsa:3597 IL13RA1; interleukin 13 receptor subunit alpha 1 hsa:3600 IL15; interleukin 15 hsa:3605 IL17A; interleukin 17A hsa:23765 IL17RA; interleukin 17 receptor A hsa:55540 IL17RB; interleukin 17 receptor B hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3556 IL1RAP; interleukin 1 receptor accessory protein hsa:3558 IL2; interleukin 2 hsa:50616 IL22; interleukin 22 hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3624 INHBA; inhibin beta A hsa:3625 INHBB; inhibin beta B hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:3952 LEP; leptin hsa:3976 LIF; leukemia inhibitory factor hsa:4049 LTA; lymphotoxin alpha hsa:5008 OSM; oncostatin M hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:51330 TNFRSF12A; tumor necrosis factor receptor superfamily member 12A hsa:8784 TNFRSF18; tumor necrosis factor receptor superfamily member 18 hsa:3604 TNFRSF9; tumor necrosis factor receptor superfamily member 9 hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10 hsa:8600 TNFSF11; tumor necrosis factor superfamily member 11 hsa:10673 TNFSF13B; tumor necrosis factor superfamily member 13b hsa:8995 TNFSF18; tumor necrosis factor superfamily member 18 hsa:8744 TNFSF9; tumor necrosis factor superfamily member 9 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05200 Pathways in cancer - Homo sapiens (human) (81)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:650 BMP2; bone morphogenetic protein 2 hsa:652 BMP4; bone morphogenetic protein 4 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:998 CDC42; cell division cycle 42 hsa:999 CDH1; cadherin 1 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1050 CEBPA; CCAAT/enhancer binding protein alpha hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1438 CSF2RA; colony stimulating factor 2 receptor alpha subunit hsa:1499 CTNNB1; catenin beta 1 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:54205 CYCS; cytochrome c, somatic hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:112399 EGLN3; egl-9 family hypoxia inducible factor 3 (EC:1.14.11.29) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2247 FGF2; fibroblast growth factor 2 hsa:2335 FN1; fibronectin 1 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2308 FOXO1; forkhead box O1 hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3082 HGF; hepatocyte growth factor hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3569 IL6; interleukin 6 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3685 ITGAV; integrin subunit alpha V hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3728 JUP; junction plakoglobin hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:5979 RET; ret proto-oncogene (EC:2.7.10.1) hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7157 TP53; tumor protein p53 hsa:7170 TPM3; tropomyosin 3 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:7422 VEGFA; vascular endothelial growth factor A hsa:7474 WNT5A; Wnt family member 5A hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa01100 Metabolic pathways - Homo sapiens (human) (74)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16) hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:37 ACADVL; acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9) hsa:205 AK4; adenylate kinase 4 (EC:2.7.4.10 2.7.4.6) hsa:57016 AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) hsa:246 ALOX15; arachidonate 15-lipoxygenase (EC:1.13.11.31 1.13.11.33) hsa:240 ALOX5; arachidonate 5-lipoxygenase (EC:1.13.11.34) hsa:271 AMPD2; adenosine monophosphate deaminase 2 (EC:3.5.4.6) hsa:440 ASNS; asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:686 BTD; biotinidase (EC:3.5.1.12) hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:204219 CERS3; ceramide synthase 3 (EC:2.3.1.24) hsa:84735 CNDP1; carnosine dipeptidase 1 (metallopeptidase M20 family) (EC:3.4.13.20) hsa:1371 CPOX; coproporphyrinogen oxidase (EC:1.3.3.3) hsa:1491 CTH; cystathionine gamma-lyase (EC:4.4.1.1) hsa:54205 CYCS; cytochrome c, somatic hsa:1629 DBT; dihydrolipoamide branched chain transacylase E2 (EC:2.3.1.168) hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107) hsa:1807 DPYS; dihydropyrimidinase (EC:3.5.2.2) hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:2058 EPRS; glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) hsa:2131 EXT1; exostosin glycosyltransferase 1 (EC:2.4.1.225 2.4.1.224) hsa:2529 FUT7; fucosyltransferase 7 (EC:2.4.1.-) hsa:51809 GALNT7; polypeptide N-acetylgalactosaminyltransferase 7 (EC:2.4.1.41) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:283459 GATC; glutamyl-tRNA(Gln) amidotransferase, subunit C hsa:2643 GCH1; GTP cyclohydrolase 1 (EC:3.5.4.16) hsa:2651 GCNT2; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (EC:2.4.1.150) hsa:2673 GFPT1; glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16) hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31) hsa:3067 HDC; histidine decarboxylase (EC:4.1.1.22) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) hsa:51144 HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12 (EC:1.1.1.62 1.1.1.330) hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:3620 IDO1; indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52) hsa:51477 ISYNA1; inositol-3-phosphate synthase 1 (EC:5.5.1.4) hsa:3911 LAMA5; laminin subunit alpha 5 hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1) hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27) hsa:387787 LIPT2; lipoyl(octanoyl) transferase 2 (putative) (EC:2.3.1.181) hsa:79888 LPCAT1; lysophosphatidylcholine acyltransferase 1 (EC:2.3.1.23 2.3.1.67) hsa:4122 MAN2A2; mannosidase alpha class 2A member 2 (EC:3.2.1.114) hsa:25902 MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3) hsa:10797 MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15) hsa:9108 MTMR7; myotubularin related protein 7 (EC:3.1.3.-) hsa:10135 NAMPT; nicotinamide phosphoribosyltransferase (EC:2.4.2.12) hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:4953 ODC1; ornithine decarboxylase 1 (EC:4.1.1.17) hsa:8974 P4HA2; prolyl 4-hydroxylase subunit alpha 2 (EC:1.14.11.2) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:80055 PGAP1; post-GPI attachment to proteins 1 hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3) hsa:5277 PIGA; phosphatidylinositol glycan anchor biosynthesis class A (EC:2.4.1.198) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4) hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52) hsa:9536 PTGES; prostaglandin E synthase (EC:5.3.99.3) hsa:5834 PYGB; phosphorylase, glycogen; brain (EC:2.4.1.1) hsa:22928 SEPHS2; selenophosphate synthetase 2 (EC:2.7.9.3) hsa:55627 SMPD4; sphingomyelin phosphodiesterase 4 (EC:3.1.4.12) hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2 (EC:2.3.1.50) hsa:6482 ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (EC:2.4.99.4) hsa:27090 ST6GALNAC4; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (EC:2.4.99.7) hsa:201595 STT3B; STT3B, catalytic subunit of the oligosaccharyltransferase complex (EC:2.4.99.18) hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1) hsa:7371 UCK2; uridine-cytidine kinase 2 (EC:2.7.1.48) hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa05152 Tuberculosis - Homo sapiens (human) (72)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:8915 BCL10; B-cell CLL/lymphoma 10 hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:820 CAMP; cathelicidin antimicrobial peptide hsa:64170 CARD9; caspase recruitment domain family member 9 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:929 CD14; CD14 molecule hsa:30835 CD209; CD209 molecule hsa:972 CD74; CD74 molecule hsa:1051 CEBPB; CCAAT/enhancer binding protein beta hsa:26253 CLEC4E; C-type lectin domain family 4 member E hsa:64581 CLEC7A; C-type lectin domain family 7 member A hsa:11151 CORO1A; coronin 1A hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1509 CTSD; cathepsin D (EC:3.4.23.5) hsa:54205 CYCS; cytochrome c, somatic hsa:8411 EEA1; early endosome antigen 1 hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3313 HSPA9; heat shock protein family A (Hsp70) member 9 hsa:3329 HSPD1; heat shock protein family D (Hsp60) member 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3684 ITGAM; integrin subunit alpha M hsa:3687 ITGAX; integrin subunit alpha X hsa:3689 ITGB2; integrin subunit beta 2 hsa:3916 LAMP1; lysosomal associated membrane protein 1 hsa:3929 LBP; lipopolysaccharide binding protein hsa:10892 MALT1; MALT1 paracaspase (EC:3.4.22.-) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4360 MRC1; mannose receptor, C type 1 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:64127 NOD2; nucleotide binding oligomerization domain containing 2 hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:1263 PLK3; polo like kinase 3 (EC:2.7.11.21) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:10333 TLR6; toll like receptor 6 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human) (72)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:10018 BCL2L11; BCL2 like 11 hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1440 CSF3; colony stimulating factor 3 hsa:54541 DDIT4; DNA damage inducible transcript 4 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:1969 EPHA2; EPH receptor A2 (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:356 FASLG; Fas ligand hsa:2247 FGF2; fibroblast growth factor 2 hsa:2324 FLT4; fms related tyrosine kinase 4 (EC:2.7.10.1) hsa:2335 FN1; fibronectin 1 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3558 IL2; interleukin 2 hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4170 MCL1; myeloid cell leukemia 1 hsa:4193 MDM2; MDM2 proto-oncogene hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:3164 NR4A1; nuclear receptor subfamily 4 group A member 1 hsa:5008 OSM; oncostatin M hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:5649 RELN; reelin hsa:6446 SGK1; serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) hsa:6696 SPP1; secreted phosphoprotein 1 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7010 TEK; TEK receptor tyrosine kinase (EC:2.7.10.1) hsa:7057 THBS1; thrombospondin 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:3371 TNC; tenascin C hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A hsa:7448 VTN; vitronectin hsa:7450 VWF; von Willebrand factor hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa05164 Influenza A - Homo sapiens (human) (68)

hsa:60 ACTB; actin, beta hsa:103 ADAR; adenosine deaminase, RNA-specific (EC:3.5.4.37) hsa:3267 AGFG1; ArfGAP with FG repeats 1 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:54205 CYCS; cytochrome c, somatic hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:64135 IFIH1; interferon induced with helicase C domain 1 (EC:3.6.4.13) hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:90865 IL33; interleukin 33 hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3665 IRF7; interferon regulatory factor 7 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4599 MX1; MX dynamin like GTPase 1 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:114548 NLRP3; NLR family, pyrin domain containing 3 hsa:4938 OAS1; 2'-5'-oligoadenylate synthetase 1 (EC:2.7.7.84) hsa:4939 OAS2; 2'-5'-oligoadenylate synthetase 2 (EC:2.7.7.84) hsa:4940 OAS3; 2'-5'-oligoadenylate synthetase 3 (EC:2.7.7.84) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:91543 RSAD2; radical S-adenosyl methionine domain containing 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7098 TLR3; toll like receptor 3 hsa:7099 TLR4; toll like receptor 4 hsa:51284 TLR7; toll like receptor 7 hsa:7124 TNF; tumor necrosis factor hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10 hsa:7706 TRIM25; tripartite motif containing 25 (EC:6.3.2.n3 2.3.2.27)

hsa04062 Chemokine signaling pathway - Homo sapiens (human) (64)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:6346 CCL1; C-C motif chemokine ligand 1 hsa:6356 CCL11; C-C motif chemokine ligand 11 hsa:6357 CCL13; C-C motif chemokine ligand 13 hsa:6362 CCL18; C-C motif chemokine ligand 18 hsa:6363 CCL19; C-C motif chemokine ligand 19 hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6364 CCL20; C-C motif chemokine ligand 20 hsa:6366 CCL21; C-C motif chemokine ligand 21 hsa:6367 CCL22; C-C motif chemokine ligand 22 hsa:6369 CCL24; C-C motif chemokine ligand 24 hsa:10344 CCL26; C-C motif chemokine ligand 26 hsa:56477 CCL28; C-C motif chemokine ligand 28 hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:6354 CCL7; C-C motif chemokine ligand 7 hsa:6355 CCL8; C-C motif chemokine ligand 8 hsa:1230 CCR1; C-C motif chemokine receptor 1 hsa:729230 CCR2; C-C motif chemokine receptor 2 hsa:1234 CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) hsa:1236 CCR7; C-C motif chemokine receptor 7 hsa:998 CDC42; cell division cycle 42 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:6376 CX3CL1; C-X3-C motif chemokine ligand 1 hsa:1524 CX3CR1; C-X3-C motif chemokine receptor 1 hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:6373 CXCL11; C-X-C motif chemokine ligand 11 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:10563 CXCL13; C-X-C motif chemokine ligand 13 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:2921 CXCL3; C-X-C motif chemokine ligand 3 hsa:6374 CXCL5; C-X-C motif chemokine ligand 5 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:4283 CXCL9; C-X-C motif chemokine ligand 9 hsa:3579 CXCR2; C-X-C motif chemokine receptor 2 hsa:2833 CXCR3; C-X-C motif chemokine receptor 3 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:643 CXCR5; C-X-C motif chemokine receptor 5 hsa:1794 DOCK2; dedicator of cytokinesis 2 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3 hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04610 Complement and coagulation cascades - Homo sapiens (human) (60)

hsa:2 A2M; alpha-2-macroglobulin hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:712 C1QA; complement component 1, q subcomponent, A chain hsa:713 C1QB; complement component 1, q subcomponent, B chain hsa:714 C1QC; complement component 1, q subcomponent, C chain hsa:715 C1R; complement C1r subcomponent (EC:3.4.21.41) hsa:716 C1S; complement component 1, s subcomponent (EC:3.4.21.42) hsa:717 C2; complement component 2 (EC:3.4.21.43) hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:720 C4A; complement component 4A (Rodgers blood group) hsa:721 C4B; complement component 4B (Chido blood group) hsa:722 C4BPA; complement component 4 binding protein alpha hsa:725 C4BPB; complement component 4 binding protein beta hsa:727 C5; complement component 5 hsa:729 C6; complement component 6 hsa:730 C7; complement component 7 hsa:731 C8A; complement component 8 alpha subunit hsa:732 C8B; complement component 8, beta polypeptide hsa:733 C8G; complement component 8, gamma polypeptide hsa:735 C9; complement component 9 hsa:629 CFB; complement factor B (EC:3.4.21.47) hsa:1675 CFD; complement factor D (EC:3.4.21.46) hsa:3075 CFH; complement factor H (EC:4.2.1.2) hsa:3426 CFI; complement factor I (EC:3.4.21.45) hsa:1191 CLU; clusterin hsa:1361 CPB2; carboxypeptidase B2 (EC:3.4.17.20) hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:2159 F10; coagulation factor X (EC:3.4.21.6) hsa:2161 F12; coagulation factor XII (EC:3.4.21.38) hsa:2165 F13B; coagulation factor XIII B chain (EC:2.3.2.13) hsa:2147 F2; coagulation factor II, thrombin (EC:3.4.21.5) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2152 F3; coagulation factor III, tissue factor hsa:2153 F5; coagulation factor V hsa:2155 F7; coagulation factor VII (EC:3.4.21.21) hsa:2158 F9; coagulation factor IX (EC:3.4.21.22) hsa:2243 FGA; fibrinogen alpha chain hsa:2244 FGB; fibrinogen beta chain hsa:2266 FGG; fibrinogen gamma chain hsa:3684 ITGAM; integrin subunit alpha M hsa:3687 ITGAX; integrin subunit alpha X hsa:3689 ITGB2; integrin subunit beta 2 hsa:3818 KLKB1; kallikrein B1 (EC:3.4.21.34) hsa:3827 KNG1; kininogen 1 hsa:10747 MASP2; mannan binding lectin serine peptidase 2 (EC:3.4.21.104) hsa:4153 MBL2; mannose binding lectin 2 hsa:5329 PLAUR; plasminogen activator, urokinase receptor hsa:10544 PROCR; protein C receptor hsa:5265 SERPINA1; serpin family A member 1 hsa:5104 SERPINA5; serpin family A member 5 hsa:462 SERPINC1; serpin family C member 1 hsa:3053 SERPIND1; serpin family D member 1 hsa:5054 SERPINE1; serpin family E member 1 hsa:5345 SERPINF2; serpin family F member 2 hsa:710 SERPING1; serpin family G member 1 hsa:7035 TFPI; tissue factor pathway inhibitor hsa:11326 VSIG4; V-set and immunoglobulin domain containing 4 hsa:7448 VTN; vitronectin hsa:7450 VWF; von Willebrand factor

hsa05168 Herpes simplex infection - Homo sapiens (human) (58)

hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:727 C5; complement component 5 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:972 CD74; CD74 molecule hsa:5199 CFP; complement factor properdin hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:54205 CYCS; cytochrome c, somatic hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3150 HMGN1; high mobility group nucleosome binding domain 1 hsa:64135 IFIH1; interferon induced with helicase C domain 1 (EC:3.6.4.13) hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3600 IL15; interleukin 15 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3665 IRF7; interferon regulatory factor 7 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4049 LTA; lymphotoxin alpha hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:4938 OAS1; 2'-5'-oligoadenylate synthetase 1 (EC:2.7.7.84) hsa:4939 OAS2; 2'-5'-oligoadenylate synthetase 2 (EC:2.7.7.84) hsa:4940 OAS3; 2'-5'-oligoadenylate synthetase 3 (EC:2.7.7.84) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6890 TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7097 TLR2; toll like receptor 2 hsa:7098 TLR3; toll like receptor 3 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04010 MAPK signaling pathway - Homo sapiens (human) (55)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:929 CD14; CD14 molecule hsa:998 CDC42; cell division cycle 42 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1843 DUSP1; dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) hsa:11221 DUSP10; dual specificity phosphatase 10 (EC:3.1.3.16 3.1.3.48) hsa:80824 DUSP16; dual specificity phosphatase 16 (EC:3.1.3.16 3.1.3.48) hsa:1844 DUSP2; dual specificity phosphatase 2 (EC:3.1.3.16 3.1.3.48) hsa:1846 DUSP4; dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48) hsa:1847 DUSP5; dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48) hsa:1848 DUSP6; dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) hsa:1850 DUSP8; dual specificity phosphatase 8 (EC:3.1.3.16 3.1.3.48) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2247 FGF2; fibroblast growth factor 2 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:1647 GADD45A; growth arrest and DNA damage inducible alpha hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:10912 GADD45G; growth arrest and DNA damage inducible gamma hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:10746 MAP3K2; mitogen-activated protein kinase kinase kinase 2 (EC:2.7.11.25) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4208 MEF2C; myocyte enhancer factor 2C hsa:2872 MKNK2; MAP kinase interacting serine/threonine kinase 2 (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:3164 NR4A1; nuclear receptor subfamily 4 group A member 1 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:9693 RAPGEF2; Rap guanine nucleotide exchange factor 2 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6722 SRF; serum response factor hsa:3925 STMN1; stathmin 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:7189 TRAF6; TNF receptor associated factor 6

hsa05161 Hepatitis B - Homo sapiens (human) (52)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:54205 CYCS; cytochrome c, somatic hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:1959 EGR2; early growth response 2 hsa:1960 EGR3; early growth response 3 hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:64135 IFIH1; interferon induced with helicase C domain 1 (EC:3.6.4.13) hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3569 IL6; interleukin 6 hsa:3665 IRF7; interferon regulatory factor 7 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:6775 STAT4; signal transducer and activator of transcription 4 hsa:6778 STAT6; signal transducer and activator of transcription 6 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7097 TLR2; toll like receptor 2 hsa:7098 TLR3; toll like receptor 3 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa05162 Measles - Homo sapiens (human) (52)

hsa:103 ADAR; adenosine deaminase, RNA-specific (EC:3.5.4.37) hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:30835 CD209; CD209 molecule hsa:940 CD28; CD28 molecule hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:1796 DOK1; docking protein 1 hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:64135 IFIH1; interferon induced with helicase C domain 1 (EC:3.6.4.13) hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3596 IL13; interleukin 13 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3558 IL2; interleukin 2 hsa:3565 IL4; interleukin 4 hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3665 IRF7; interferon regulatory factor 7 hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:4599 MX1; MX dynamin like GTPase 1 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:4938 OAS1; 2'-5'-oligoadenylate synthetase 1 (EC:2.7.7.84) hsa:4939 OAS2; 2'-5'-oligoadenylate synthetase 2 (EC:2.7.7.84) hsa:4940 OAS3; 2'-5'-oligoadenylate synthetase 3 (EC:2.7.7.84) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:51284 TLR7; toll like receptor 7 hsa:54106 TLR9; toll like receptor 9 hsa:7128 TNFAIP3; TNF alpha induced protein 3 (EC:3.4.19.12) hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10 hsa:7157 TP53; tumor protein p53 hsa:7189 TRAF6; TNF receptor associated factor 6

hsa05205 Proteoglycans in cancer - Homo sapiens (human) (51)

hsa:60 ACTB; actin, beta hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:286 ANK1; ankyrin 1 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:960 CD44; CD44 molecule (Indian blood group) hsa:998 CDC42; cell division cycle 42 hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1499 CTNNB1; catenin beta 1 hsa:2017 CTTN; cortactin hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2247 FGF2; fibroblast growth factor 2 hsa:2335 FN1; fibronectin 1 hsa:8325 FZD8; frizzled class receptor 8 hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3082 HGF; hepatocyte growth factor hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3593 IL12B; interleukin 12B hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:4060 LUM; lumican hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5329 PLAUR; plasminogen activator, urokinase receptor hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6385 SDC4; syndecan 4 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7057 THBS1; thrombospondin 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A hsa:7448 VTN; vitronectin hsa:7474 WNT5A; Wnt family member 5A

hsa04668 TNF signaling pathway - Homo sapiens (human) (51)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:602 BCL3; B-cell CLL/lymphoma 3 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6364 CCL20; C-C motif chemokine ligand 20 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:1051 CEBPB; CCAAT/enhancer binding protein beta hsa:8837 CFLAR; CASP8 and FADD like apoptosis regulator hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1437 CSF2; colony stimulating factor 2 hsa:6376 CX3CL1; C-X3-C motif chemokine ligand 1 hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:2921 CXCL3; C-X-C motif chemokine ligand 3 hsa:6374 CXCL5; C-X-C motif chemokine ligand 5 hsa:1906 EDN1; endothelin 1 hsa:355 FAS; Fas cell surface death receptor hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3600 IL15; interleukin 15 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3726 JUNB; JunB proto-oncogene, AP-1 transcription factor subunit hsa:3976 LIF; leukemia inhibitory factor hsa:4049 LTA; lymphotoxin alpha hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4314 MMP3; matrix metallopeptidase 3 (EC:3.4.24.17) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:64127 NOD2; nucleotide binding oligomerization domain containing 2 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:7124 TNF; tumor necrosis factor hsa:7128 TNFAIP3; TNF alpha induced protein 3 (EC:3.4.19.12) hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa05145 Toxoplasmosis - Homo sapiens (human) (50)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:240 ALOX5; arachidonate 5-lipoxygenase (EC:1.13.11.34) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1234 CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:54205 CYCS; cytochrome c, somatic hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa05166 HTLV-I infection - Homo sapiens (human) (49)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:467 ATF3; activating transcription factor 3 hsa:468 ATF4; activating transcription factor 4 hsa:958 CD40; CD40 molecule hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1390 CREM; cAMP responsive element modulator hsa:1437 CSF2; colony stimulating factor 2 hsa:1499 CTNNB1; catenin beta 1 hsa:1958 EGR1; early growth response 1 hsa:1959 EGR2; early growth response 2 hsa:2114 ETS2; ETS proto-oncogene 2, transcription factor hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:8061 FOSL1; FOS like 1, AP-1 trancription factor subunit hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3600 IL15; interleukin 15 hsa:3558 IL2; interleukin 2 hsa:3569 IL6; interleukin 6 hsa:3689 ITGB2; integrin subunit beta 2 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4049 LTA; lymphotoxin alpha hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6722 SRF; serum response factor hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7094 TLN1; talin 1 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:7412 VCAM1; vascular cell adhesion molecule 1 hsa:7474 WNT5A; Wnt family member 5A hsa:331 XIAP; X-linked inhibitor of apoptosis hsa:7538 ZFP36; ZFP36 ring finger protein

hsa04380 Osteoclast differentiation - Homo sapiens (human) (49)

hsa:54 ACP5; acid phosphatase 5, tartrate resistant (EC:3.1.3.2) hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1535 CYBA; cytochrome b-245 alpha chain hsa:1536 CYBB; cytochrome b-245 beta chain hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:8061 FOSL1; FOS like 1, AP-1 trancription factor subunit hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3690 ITGB3; integrin subunit beta 3 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3726 JUNB; JunB proto-oncogene, AP-1 transcription factor subunit hsa:11006 LILRB4; leukocyte immunoglobulin like receptor B4 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:4688 NCF2; neutrophil cytosolic factor 2 hsa:4689 NCF4; neutrophil cytosolic factor 4 hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:8878 SQSTM1; sequestosome 1 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:8600 TNFSF11; tumor necrosis factor superfamily member 11 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:7305 TYROBP; TYRO protein tyrosine kinase binding protein

hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human) (48)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:929 CD14; CD14 molecule hsa:958 CD40; CD40 molecule hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:6373 CXCL11; C-X-C motif chemokine ligand 11 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:4283 CXCL9; C-X-C motif chemokine ligand 9 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3665 IRF7; interferon regulatory factor 7 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3929 LBP; lipopolysaccharide binding protein hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6696 SPP1; secreted phosphoprotein 1 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7097 TLR2; toll like receptor 2 hsa:7098 TLR3; toll like receptor 3 hsa:7099 TLR4; toll like receptor 4 hsa:10333 TLR6; toll like receptor 6 hsa:51284 TLR7; toll like receptor 7 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04145 Phagosome - Homo sapiens (human) (48)

hsa:60 ACTB; actin, beta hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:715 C1R; complement C1r subcomponent (EC:3.4.21.41) hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:929 CD14; CD14 molecule hsa:30835 CD209; CD209 molecule hsa:948 CD36; CD36 molecule hsa:64581 CLEC7A; C-type lectin domain family 7 member A hsa:78989 COLEC11; collectin subfamily member 11 hsa:11151 CORO1A; coronin 1A hsa:1535 CYBA; cytochrome b-245 alpha chain hsa:1536 CYBB; cytochrome b-245 beta chain hsa:8411 EEA1; early endosome antigen 1 hsa:2204 FCAR; Fc fragment of IgA receptor hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3685 ITGAV; integrin subunit alpha V hsa:3689 ITGB2; integrin subunit beta 2 hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:3916 LAMP1; lysosomal associated membrane protein 1 hsa:8685 MARCO; macrophage receptor with collagenous structure hsa:4153 MBL2; mannose binding lectin 2 hsa:4353 MPO; myeloperoxidase (EC:1.11.2.2) hsa:4360 MRC1; mannose receptor, C type 1 hsa:4481 MSR1; macrophage scavenger receptor 1 hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:4688 NCF2; neutrophil cytosolic factor 2 hsa:4689 NCF4; neutrophil cytosolic factor 4 hsa:4973 OLR1; oxidized low density lipoprotein receptor 1 hsa:6441 SFTPD; surfactant protein D hsa:6890 TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) hsa:7037 TFRC; transferrin receptor hsa:7057 THBS1; thrombospondin 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:10333 TLR6; toll like receptor 6 hsa:7277 TUBA4A; tubulin alpha 4a hsa:203068 TUBB; tubulin beta class I hsa:84617 TUBB6; tubulin beta 6 class V hsa:9341 VAMP3; vesicle associated membrane protein 3

hsa05133 Pertussis - Homo sapiens (human) (47)

hsa:712 C1QA; complement component 1, q subcomponent, A chain hsa:713 C1QB; complement component 1, q subcomponent, B chain hsa:714 C1QC; complement component 1, q subcomponent, C chain hsa:715 C1R; complement C1r subcomponent (EC:3.4.21.41) hsa:716 C1S; complement component 1, s subcomponent (EC:3.4.21.42) hsa:717 C2; complement component 2 (EC:3.4.21.43) hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:720 C4A; complement component 4A (Rodgers blood group) hsa:721 C4B; complement component 4B (Chido blood group) hsa:722 C4BPA; complement component 4 binding protein alpha hsa:725 C4BPB; complement component 4 binding protein beta hsa:727 C5; complement component 5 hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:929 CD14; CD14 molecule hsa:1072 CFL1; cofilin 1 hsa:6374 CXCL5; C-X-C motif chemokine ligand 5 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3659 IRF1; interferon regulatory factor 1 hsa:3394 IRF8; interferon regulatory factor 8 hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:114548 NLRP3; NLR family, pyrin domain containing 3 hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:710 SERPING1; serpin family G member 1 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6

hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human) (46)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:624 BDKRB2; bradykinin receptor B2 hsa:712 C1QA; complement component 1, q subcomponent, A chain hsa:713 C1QB; complement component 1, q subcomponent, B chain hsa:714 C1QC; complement component 1, q subcomponent, C chain hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:8837 CFLAR; CASP8 and FADD like apoptosis regulator hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3553 IL1B; interleukin 1 beta hsa:3558 IL2; interleukin 2 hsa:3569 IL6; interleukin 6 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:5054 SERPINE1; serpin family E member 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:10333 TLR6; toll like receptor 6 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04510 Focal adhesion - Homo sapiens (human) (45)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:998 CDC42; cell division cycle 42 hsa:1499 CTNNB1; catenin beta 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2324 FLT4; fms related tyrosine kinase 4 (EC:2.7.10.1) hsa:2335 FN1; fibronectin 1 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5649 RELN; reelin hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6696 SPP1; secreted phosphoprotein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7057 THBS1; thrombospondin 1 hsa:7094 TLN1; talin 1 hsa:3371 TNC; tenascin C hsa:7408 VASP; vasodilator-stimulated phosphoprotein hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3 hsa:7414 VCL; vinculin hsa:7422 VEGFA; vascular endothelial growth factor A hsa:7448 VTN; vitronectin hsa:7450 VWF; von Willebrand factor hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa05140 Leishmaniasis - Homo sapiens (human) (44)

hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:1535 CYBA; cytochrome b-245 alpha chain hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3565 IL4; interleukin 4 hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:65108 MARCKSL1; MARCKS-like 1 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:4688 NCF2; neutrophil cytosolic factor 2 hsa:4689 NCF4; neutrophil cytosolic factor 4 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04064 NF-kappa B signaling pathway - Homo sapiens (human) (43)

hsa:8915 BCL10; B-cell CLL/lymphoma 10 hsa:597 BCL2A1; BCL2 related protein A1 hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:6357 CCL13; C-C motif chemokine ligand 13 hsa:6363 CCL19; C-C motif chemokine ligand 19 hsa:6366 CCL21; C-C motif chemokine ligand 21 hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:929 CD14; CD14 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:8837 CFLAR; CASP8 and FADD like apoptosis regulator hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3553 IL1B; interleukin 1 beta hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3929 LBP; lipopolysaccharide binding protein hsa:4049 LTA; lymphotoxin alpha hsa:10892 MALT1; MALT1 paracaspase (EC:3.4.22.-) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7128 TNFAIP3; TNF alpha induced protein 3 (EC:3.4.19.12) hsa:8600 TNFSF11; tumor necrosis factor superfamily member 11 hsa:10673 TNFSF13B; tumor necrosis factor superfamily member 13b hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:7706 TRIM25; tripartite motif containing 25 (EC:6.3.2.n3 2.3.2.27) hsa:7412 VCAM1; vascular cell adhesion molecule 1 hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa05169 Epstein-Barr virus infection - Homo sapiens (human) (43)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:958 CD40; CD40 molecule hsa:960 CD44; CD44 molecule (Indian blood group) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3586 IL10; interleukin 10 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7128 TNFAIP3; TNF alpha induced protein 3 (EC:3.4.19.12) hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:7431 VIM; vimentin hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa05323 Rheumatoid arthritis - Homo sapiens (human) (42)

hsa:54 ACP5; acid phosphatase 5, tartrate resistant (EC:3.1.3.2) hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6364 CCL20; C-C motif chemokine ligand 20 hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:940 CD28; CD28 molecule hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1437 CSF2; colony stimulating factor 2 hsa:1493 CTLA4; cytotoxic T-lymphocyte associated protein 4 hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:6374 CXCL5; C-X-C motif chemokine ligand 5 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3458 IFNG; interferon, gamma hsa:3600 IL15; interleukin 15 hsa:3605 IL17A; interleukin 17A hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3569 IL6; interleukin 6 hsa:3689 ITGB2; integrin subunit beta 2 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4314 MMP3; matrix metallopeptidase 3 (EC:3.4.24.17) hsa:7010 TEK; TEK receptor tyrosine kinase (EC:2.7.10.1) hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:8600 TNFSF11; tumor necrosis factor superfamily member 11 hsa:10673 TNFSF13B; tumor necrosis factor superfamily member 13b hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04015 Rap1 signaling pathway - Homo sapiens (human) (41)

hsa:60 ACTB; actin, beta hsa:135 ADORA2A; adenosine A2a receptor hsa:136 ADORA2B; adenosine A2b receptor hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:54518 APBB1IP; amyloid beta precursor protein binding family B member 1 interacting protein hsa:998 CDC42; cell division cycle 42 hsa:999 CDH1; cadherin 1 hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1499 CTNNB1; catenin beta 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1969 EPHA2; EPH receptor A2 (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2247 FGF2; fibroblast growth factor 2 hsa:2324 FLT4; fms related tyrosine kinase 4 (EC:2.7.10.1) hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3397 ID1; inhibitor of DNA binding 1, HLH protein hsa:3479 IGF1; insulin like growth factor 1 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:3690 ITGB3; integrin subunit beta 3 hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:9693 RAPGEF2; Rap guanine nucleotide exchange factor 2 hsa:387 RHOA; ras homolog family member A hsa:26037 SIPA1L1; signal induced proliferation associated 1 like 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7010 TEK; TEK receptor tyrosine kinase (EC:2.7.10.1) hsa:7057 THBS1; thrombospondin 1 hsa:7094 TLN1; talin 1 hsa:7408 VASP; vasodilator-stimulated phosphoprotein hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04210 Apoptosis - Homo sapiens (human) (41)

hsa:60 ACTB; actin, beta hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:597 BCL2A1; BCL2 related protein A1 hsa:10018 BCL2L11; BCL2 like 11 hsa:835 CASP2; caspase 2 (EC:3.4.22.55) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:8837 CFLAR; CASP8 and FADD like apoptosis regulator hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1509 CTSD; cathepsin D (EC:3.4.23.5) hsa:54205 CYCS; cytochrome c, somatic hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:1647 GADD45A; growth arrest and DNA damage inducible alpha hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:10912 GADD45G; growth arrest and DNA damage inducible gamma hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3562 IL3; interleukin 3 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4000 LMNA; lamin A/C hsa:4001 LMNB1; lamin B1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4170 MCL1; myeloid cell leukemia 1 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7124 TNF; tumor necrosis factor hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10 hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7277 TUBA4A; tubulin alpha 4a hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa04066 HIF-1 signaling pathway - Homo sapiens (human) (40)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1536 CYBB; cytochrome b-245 beta chain hsa:1906 EDN1; endothelin 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:112399 EGLN3; egl-9 family hypoxia inducible factor 3 (EC:1.14.11.29) hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3) hsa:3458 IFNG; interferon, gamma hsa:3479 IGF1; insulin like growth factor 1 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2872 MKNK2; MAP kinase interacting serine/threonine kinase 2 (EC:2.7.11.1) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:5054 SERPINE1; serpin family E member 1 hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7010 TEK; TEK receptor tyrosine kinase (EC:2.7.10.1) hsa:7018 TF; transferrin hsa:7037 TFRC; transferrin receptor hsa:7076 TIMP1; TIMP metallopeptidase inhibitor 1 hsa:7099 TLR4; toll like receptor 4 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04630 Jak-STAT signaling pathway - Homo sapiens (human) (39)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1154 CISH; cytokine inducible SH2 containing protein hsa:1437 CSF2; colony stimulating factor 2 hsa:1438 CSF2RA; colony stimulating factor 2 receptor alpha subunit hsa:1440 CSF3; colony stimulating factor 3 hsa:2273 FHL1; four and a half LIM domains 1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3596 IL13; interleukin 13 hsa:3597 IL13RA1; interleukin 13 receptor subunit alpha 1 hsa:3600 IL15; interleukin 15 hsa:3558 IL2; interleukin 2 hsa:50616 IL22; interleukin 22 hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3952 LEP; leptin hsa:3976 LIF; leukemia inhibitory factor hsa:4170 MCL1; myeloid cell leukemia 1 hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5008 OSM; oncostatin M hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:8835 SOCS2; suppressor of cytokine signaling 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:6775 STAT4; signal transducer and activator of transcription 4 hsa:6778 STAT6; signal transducer and activator of transcription 6

hsa04660 T cell receptor signaling pathway - Homo sapiens (human) (37)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:8915 BCL10; B-cell CLL/lymphoma 10 hsa:940 CD28; CD28 molecule hsa:920 CD4; CD4 molecule hsa:959 CD40LG; CD40 ligand hsa:998 CDC42; cell division cycle 42 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1437 CSF2; colony stimulating factor 2 hsa:1493 CTLA4; cytotoxic T-lymphocyte associated protein 4 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3458 IFNG; interferon, gamma hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3586 IL10; interleukin 10 hsa:3558 IL2; interleukin 2 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:10892 MALT1; MALT1 paracaspase (EC:3.4.22.-) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:7124 TNF; tumor necrosis factor hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3

hsa05203 Viral carcinogenesis - Homo sapiens (human) (37)

hsa:87 ACTN1; actinin alpha 1 hsa:468 ATF4; activating transcription factor 4 hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:1234 CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) hsa:998 CDC42; cell division cycle 42 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1959 EGR2; early growth response 2 hsa:1960 EGR3; early growth response 3 hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:2934 GSN; gelsolin hsa:85236 HIST1H2BK; histone cluster 1, H2bk hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3665 IRF7; interferon regulatory factor 7 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5933 RBL1; retinoblastoma-like 1 hsa:5966 REL; REL proto-oncogene, NF-kB subunit hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6722 SRF; serum response factor hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa05322 Systemic lupus erythematosus - Homo sapiens (human) (37)

hsa:87 ACTN1; actinin alpha 1 hsa:712 C1QA; complement component 1, q subcomponent, A chain hsa:713 C1QB; complement component 1, q subcomponent, B chain hsa:714 C1QC; complement component 1, q subcomponent, C chain hsa:715 C1R; complement C1r subcomponent (EC:3.4.21.41) hsa:716 C1S; complement component 1, s subcomponent (EC:3.4.21.42) hsa:717 C2; complement component 2 (EC:3.4.21.43) hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:720 C4A; complement component 4A (Rodgers blood group) hsa:721 C4B; complement component 4B (Chido blood group) hsa:727 C5; complement component 5 hsa:729 C6; complement component 6 hsa:730 C7; complement component 7 hsa:731 C8A; complement component 8 alpha subunit hsa:732 C8B; complement component 8, beta polypeptide hsa:733 C8G; complement component 8, gamma polypeptide hsa:735 C9; complement component 9 hsa:940 CD28; CD28 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:1511 CTSG; cathepsin G (EC:3.4.21.20) hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:85235 HIST1H2AH; histone cluster 1, H2ah hsa:85236 HIST1H2BK; histone cluster 1, H2bk hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:7124 TNF; tumor necrosis factor hsa:6737 TRIM21; tripartite motif containing 21

hsa04640 Hematopoietic cell lineage - Homo sapiens (human) (36)

hsa:929 CD14; CD14 molecule hsa:909 CD1A; CD1a molecule hsa:912 CD1D; CD1d molecule hsa:913 CD1E; CD1e molecule hsa:945 CD33; CD33 molecule hsa:948 CD36; CD36 molecule hsa:951 CD37; CD37 molecule hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:920 CD4; CD4 molecule hsa:960 CD44; CD44 molecule (Indian blood group) hsa:921 CD5; CD5 molecule hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1437 CSF2; colony stimulating factor 2 hsa:1438 CSF2RA; colony stimulating factor 2 receptor alpha subunit hsa:1440 CSF3; colony stimulating factor 3 hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2814 GP5; glycoprotein V platelet hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3690 ITGB3; integrin subunit beta 3 hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:7037 TFRC; transferrin receptor hsa:7124 TNF; tumor necrosis factor

hsa05206 MicroRNAs in cancer - Homo sapiens (human) (36)

hsa:10018 BCL2L11; BCL2 like 11 hsa:90427 BMF; Bcl2 modifying factor hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:960 CD44; CD44 molecule (Indian blood group) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:54541 DDIT4; DNA damage inducible transcript 4 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:10642 IGF2BP1; insulin like growth factor 2 mRNA binding protein 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3690 ITGB3; integrin subunit beta 3 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:4170 MCL1; myeloid cell leukemia 1 hsa:4193 MDM2; MDM2 proto-oncogene hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4851 NOTCH1; notch 1 hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6541 SLC7A1; solute carrier family 7 member 1 hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:10253 SPRY2; sprouty RTK signaling antagonist 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:3925 STMN1; stathmin 1 hsa:7057 THBS1; thrombospondin 1 hsa:3371 TNC; tenascin C hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A hsa:7431 VIM; vimentin

hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human) (36)

hsa:597 BCL2A1; BCL2 related protein A1 hsa:1236 CCR7; C-C motif chemokine receptor 7 hsa:929 CD14; CD14 molecule hsa:958 CD40; CD40 molecule hsa:942 CD86; CD86 molecule hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1050 CEBPA; CCAAT/enhancer binding protein alpha hsa:1051 CEBPB; CCAAT/enhancer binding protein beta hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1437 CSF2; colony stimulating factor 2 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:84444 DOT1L; DOT1 like histone lysine methyltransferase (EC:2.1.1.43) hsa:1848 DUSP6; dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2308 FOXO1; forkhead box O1 hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3398 ID2; inhibitor of DNA binding 2, HLH protein hsa:3479 IGF1; insulin like growth factor 1 hsa:3562 IL3; interleukin 3 hsa:3569 IL6; interleukin 6 hsa:3684 ITGAM; integrin subunit alpha M hsa:3728 JUP; junction plakoglobin hsa:4193 MDM2; MDM2 proto-oncogene hsa:4208 MEF2C; myocyte enhancer factor 2C hsa:4314 MMP3; matrix metallopeptidase 3 (EC:3.4.24.17) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:4353 MPO; myeloperoxidase (EC:1.11.2.2) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:8013 NR4A3; nuclear receptor subfamily 4 group A member 3 hsa:26471 NUPR1; nuclear protein 1, transcriptional regulator hsa:5087 PBX1; pre-B-cell leukemia homeobox 1 hsa:5966 REL; REL proto-oncogene, NF-kB subunit hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1

hsa05160 Hepatitis C - Homo sapiens (human) (36)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3659 IRF1; interferon regulatory factor 1 hsa:3665 IRF7; interferon regulatory factor 7 hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4938 OAS1; 2'-5'-oligoadenylate synthetase 1 (EC:2.7.7.84) hsa:4939 OAS2; 2'-5'-oligoadenylate synthetase 2 (EC:2.7.7.84) hsa:4940 OAS3; 2'-5'-oligoadenylate synthetase 3 (EC:2.7.7.84) hsa:100506658 OCLN; occludin (EC:2.1.1.67) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6773 STAT2; signal transducer and activator of transcription 2 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:148022 TICAM1; toll like receptor adaptor molecule 1 hsa:7098 TLR3; toll like receptor 3 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53 hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human) (36)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6 hsa:8874 ARHGEF7; Rho guanine nucleotide exchange factor 7 hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:929 CD14; CD14 molecule hsa:998 CDC42; cell division cycle 42 hsa:1072 CFL1; cofilin 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2147 F2; coagulation factor II, thrombin (EC:3.4.21.5) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2247 FGF2; fibroblast growth factor 2 hsa:2335 FN1; fibronectin 1 hsa:2934 GSN; gelsolin hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3685 ITGAV; integrin subunit alpha V hsa:3687 ITGAX; integrin subunit alpha X hsa:3689 ITGB2; integrin subunit beta 2 hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3 hsa:7414 VCL; vinculin hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04014 Ras signaling pathway - Homo sapiens (human) (35)

hsa:27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:8315 BRAP; BRCA1 associated protein hsa:998 CDC42; cell division cycle 42 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1435 CSF1; colony stimulating factor 1 (EC:2.7.10.1) hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1969 EPHA2; EPH receptor A2 (EC:2.7.10.1) hsa:2114 ETS2; ETS proto-oncogene 2, transcription factor hsa:356 FASLG; Fas ligand hsa:2247 FGF2; fibroblast growth factor 2 hsa:2324 FLT4; fms related tyrosine kinase 4 (EC:2.7.10.1) hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4) hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:5966 REL; REL proto-oncogene, NF-kB subunit hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6464 SHC1; SHC adaptor protein 1 hsa:7010 TEK; TEK receptor tyrosine kinase (EC:2.7.10.1) hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05134 Legionellosis - Homo sapiens (human) (35)

hsa:664 BNIP3; BCL2/adenovirus E1B 19kDa interacting protein 3 hsa:718 C3; complement component 3 (EC:3.4.21.43) hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:929 CD14; CD14 molecule hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:2921 CXCL3; C-X-C motif chemokine ligand 3 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:54205 CYCS; cytochrome c, somatic hsa:1915 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3329 HSPD1; heat shock protein family D (Hsp60) member 1 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3606 IL18; interleukin 18 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:58484 NLRC4; NLR family, CARD domain containing 4 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor

hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human) (33)

hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3596 IL13; interleukin 13 hsa:3605 IL17A; interleukin 17A hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3558 IL2; interleukin 2 hsa:50616 IL22; interleukin 22 hsa:51561 IL23A; interleukin 23 subunit alpha hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3569 IL6; interleukin 6 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:64127 NOD2; nucleotide binding oligomerization domain containing 2 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6097 RORC; RAR related orphan receptor C hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:6775 STAT4; signal transducer and activator of transcription 4 hsa:6778 STAT6; signal transducer and activator of transcription 6 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor

hsa05146 Amoebiasis - Homo sapiens (human) (32)

hsa:87 ACTN1; actinin alpha 1 hsa:731 C8A; complement component 8 alpha subunit hsa:732 C8B; complement component 8, beta polypeptide hsa:733 C8G; complement component 8, gamma polypeptide hsa:735 C9; complement component 9 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:929 CD14; CD14 molecule hsa:912 CD1D; CD1d molecule hsa:1437 CSF2; colony stimulating factor 2 hsa:1511 CTSG; cathepsin G (EC:3.4.21.20) hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:2335 FN1; fibronectin 1 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:7124 TNF; tumor necrosis factor hsa:7414 VCL; vinculin

hsa04144 Endocytosis - Homo sapiens (human) (32)

hsa:23527 ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 hsa:154 ADRB2; adrenoceptor beta 2 hsa:377 ARF3; ADP ribosylation factor 3 hsa:1234 CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) hsa:998 CDC42; cell division cycle 42 hsa:51510 CHMP5; charged multivesicular body protein 5 hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1436 CSF1R; colony stimulating factor 1 receptor (EC:2.7.10.1) hsa:3579 CXCR2; C-X-C motif chemokine receptor 2 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:8411 EEA1; early endosome antigen 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:4193 MDM2; MDM2 proto-oncogene hsa:80223 RAB11FIP1; RAB11 family interacting protein 1 hsa:5979 RET; ret proto-oncogene (EC:2.7.10.1) hsa:387 RHOA; ras homolog family member A hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7037 TFRC; transferrin receptor hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human) (32)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:998 CDC42; cell division cycle 42 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:1536 CYBB; cytochrome b-245 beta chain hsa:1906 EDN1; endothelin 1 hsa:1958 EGR1; early growth response 1 hsa:2152 F3; coagulation factor III, tissue factor hsa:2335 FN1; fibronectin 1 hsa:2308 FOXO1; forkhead box O1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:5054 SERPINE1; serpin family E member 1 hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7412 VCAM1; vascular cell adhesion molecule 1 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05150 Staphylococcus aureus infection - Homo sapiens (human) (32)

hsa04068 FoxO signaling pathway - Homo sapiens (human) (31)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:10018 BCL2L11; BCL2 like 11 hsa:664 BNIP3; BCL2/adenovirus E1B 19kDa interacting protein 3 hsa:901 CCNG2; cyclin G2 hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:356 FASLG; Fas ligand hsa:2308 FOXO1; forkhead box O1 hsa:1647 GADD45A; growth arrest and DNA damage inducible alpha hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:10912 GADD45G; growth arrest and DNA damage inducible gamma hsa:9456 HOMER1; homer scaffolding protein 1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3586 IL10; interleukin 10 hsa:3569 IL6; interleukin 6 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:10769 PLK2; polo like kinase 2 (EC:2.7.11.21) hsa:1263 PLK3; polo like kinase 3 (EC:2.7.11.21) hsa:6446 SGK1; serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10

hsa05132 Salmonella infection - Homo sapiens (human) (31)

hsa:60 ACTB; actin, beta hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:6348 CCL3; C-C motif chemokine ligand 3 hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:929 CD14; CD14 molecule hsa:998 CDC42; cell division cycle 42 hsa:1437 CSF2; colony stimulating factor 2 hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:2921 CXCL3; C-X-C motif chemokine ligand 3 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3458 IFNG; interferon, gamma hsa:3606 IL18; interleukin 18 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3929 LBP; lipopolysaccharide binding protein hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:58484 NLRC4; NLR family, CARD domain containing 4 hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:7099 TLR4; toll like receptor 4 hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human) (31)

hsa:64170 CARD9; caspase recruitment domain family member 9 hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:2920 CXCL2; C-X-C motif chemokine ligand 2 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3606 IL18; interleukin 18 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:58484 NLRC4; NLR family, CARD domain containing 4 hsa:114548 NLRP3; NLR family, pyrin domain containing 3 hsa:64127 NOD2; nucleotide binding oligomerization domain containing 2 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7124 TNF; tumor necrosis factor hsa:7128 TNFAIP3; TNF alpha induced protein 3 (EC:3.4.19.12) hsa:7189 TRAF6; TNF receptor associated factor 6

hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human) (29)

hsa:214 ALCAM; activated leukocyte cell adhesion molecule hsa:940 CD28; CD28 molecule hsa:920 CD4; CD4 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:999 CDH1; cadherin 1 hsa:1000 CDH2; cadherin 2 hsa:1003 CDH5; cadherin 5 hsa:1493 CTLA4; cytotoxic T-lymphocyte associated protein 4 hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3685 ITGAV; integrin subunit alpha V hsa:3689 ITGB2; integrin subunit beta 2 hsa:9019 MPZL1; myelin protein zero like 1 hsa:4684 NCAM1; neural cell adhesion molecule 1 (EC:2.7.11.1) hsa:54413 NLGN3; neuroligin 3 hsa:100506658 OCLN; occludin (EC:2.1.1.67) hsa:5817 PVR; poliovirus receptor hsa:6385 SDC4; syndecan 4 hsa:6404 SELPLG; selectin P ligand hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human) (28)

hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:51744 CD244; CD244 molecule hsa:1437 CSF2; colony stimulating factor 2 hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2215 FCGR3B; Fc fragment of IgG receptor IIIb hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3454 IFNAR1; interferon alpha and beta receptor subunit 1 hsa:3456 IFNB1; interferon beta 1 hsa:3458 IFNG; interferon, gamma hsa:3689 ITGB2; integrin subunit beta 2 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:9437 NCR1; natural cytotoxicity triggering receptor 1 hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7124 TNF; tumor necrosis factor hsa:8743 TNFSF10; tumor necrosis factor superfamily member 10 hsa:7305 TYROBP; TYRO protein tyrosine kinase binding protein hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3

hsa04670 Leukocyte transendothelial migration - Homo sapiens (human) (28)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:998 CDC42; cell division cycle 42 hsa:1003 CDH5; cadherin 5 hsa:1499 CTNNB1; catenin beta 1 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:1535 CYBA; cytochrome b-245 alpha chain hsa:1536 CYBB; cytochrome b-245 beta chain hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3684 ITGAM; integrin subunit alpha M hsa:3689 ITGB2; integrin subunit beta 2 hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:4688 NCF2; neutrophil cytosolic factor 2 hsa:4689 NCF4; neutrophil cytosolic factor 4 hsa:100506658 OCLN; occludin (EC:2.1.1.67) hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:7408 VASP; vasodilator-stimulated phosphoprotein hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3 hsa:7412 VCAM1; vascular cell adhesion molecule 1 hsa:7414 VCL; vinculin

hsa05144 Malaria - Homo sapiens (human) (27)

hsa:6347 CCL2; C-C motif chemokine ligand 2 hsa:948 CD36; CD36 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:1378 CR1; complement component 3b/4b receptor 1 (Knops blood group) hsa:1440 CSF3; colony stimulating factor 3 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:3039 HBA1; hemoglobin subunit alpha 1 hsa:3040 HBA2; hemoglobin subunit alpha 2 hsa:3043 HBB; hemoglobin subunit beta hsa:3082 HGF; hepatocyte growth factor hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3606 IL18; interleukin 18 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3689 ITGB2; integrin subunit beta 2 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7057 THBS1; thrombospondin 1 hsa:7097 TLR2; toll like receptor 2 hsa:7099 TLR4; toll like receptor 4 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa05215 Prostate cancer - Homo sapiens (human) (27)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1499 CTNNB1; catenin beta 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2308 FOXO1; forkhead box O1 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7157 TP53; tumor protein p53

hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human) (27)

hsa:60 ACTB; actin, beta hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:652 BMP4; bone morphogenetic protein 4 hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1499 CTNNB1; catenin beta 1 hsa:2308 FOXO1; forkhead box O1 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:9969 MED13; mediator complex subunit 13 hsa:9862 MED24; mediator complex subunit 24 hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:8202 NCOA3; nuclear receptor coactivator 3 (EC:2.3.1.48) hsa:4851 NOTCH1; notch 1 hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:1827 RCAN1; regulator of calcineurin 1 hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:7157 TP53; tumor protein p53

hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human) (27)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:10018 BCL2L11; BCL2 like 11 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:998 CDC42; cell division cycle 42 hsa:1050 CEBPA; CCAAT/enhancer binding protein alpha hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:54205 CYCS; cytochrome c, somatic hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:3952 LEP; leptin hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa04662 B cell receptor signaling pathway - Homo sapiens (human) (25)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:8915 BCL10; B-cell CLL/lymphoma 10 hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:8519 IFITM1; interferon induced transmembrane protein 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3635 INPP5D; inositol polyphosphate-5-phosphatase D (EC:3.1.3.86) hsa:3636 INPPL1; inositol polyphosphate phosphatase like 1 (EC:3.1.3.86) hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:10892 MALT1; MALT1 paracaspase (EC:3.4.22.-) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3

hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) (25)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:650 BMP2; bone morphogenetic protein 2 hsa:652 BMP4; bone morphogenetic protein 4 hsa:1499 CTNNB1; catenin beta 1 hsa:2247 FGF2; fibroblast growth factor 2 hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3397 ID1; inhibitor of DNA binding 1, HLH protein hsa:3398 ID2; inhibitor of DNA binding 2, HLH protein hsa:3399 ID3; inhibitor of DNA binding 3, HLH protein hsa:3479 IGF1; insulin like growth factor 1 hsa:3624 INHBA; inhibin beta A hsa:3625 INHBB; inhibin beta B hsa:3720 JARID2; jumonji and AT-rich interaction domain containing 2 hsa:9314 KLF4; Kruppel-like factor 4 (gut) hsa:3976 LIF; leukemia inhibitory factor hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:6498 SKIL; SKI-like proto-oncogene hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7474 WNT5A; Wnt family member 5A

hsa04360 Axon guidance - Homo sapiens (human) (25)

hsa:998 CDC42; cell division cycle 42 hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.1) hsa:1072 CFL1; cofilin 1 hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:1948 EFNB2; ephrin B2 hsa:2041 EPHA1; EPH receptor A1 (EC:2.7.10.1) hsa:1969 EPHA2; EPH receptor A2 (EC:2.7.10.1) hsa:2043 EPHA4; EPH receptor A4 (EC:2.7.10.1) hsa:2046 EPHA8; EPH receptor A8 (EC:2.7.10.1) hsa:2049 EPHB3; EPH receptor B3 (EC:2.7.10.1) hsa:2050 EPHB4; EPH receptor B4 (EC:2.7.10.1) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:387 RHOA; ras homolog family member A hsa:27289 RND1; Rho family GTPase 1 hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:80031 SEMA6D; semaphorin 6D hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:219699 UNC5B; unc-5 netrin receptor B hsa:7474 WNT5A; Wnt family member 5A

hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human) (24)

hsa:9474 ATG5; autophagy related 5 hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:64135 IFIH1; interferon induced with helicase C domain 1 (EC:3.6.4.13) hsa:3456 IFNB1; interferon beta 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3665 IRF7; interferon regulatory factor 7 hsa:9636 ISG15; ISG15 ubiquitin-like modifier hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7124 TNF; tumor necrosis factor hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:7706 TRIM25; tripartite motif containing 25 (EC:6.3.2.n3 2.3.2.27)

hsa04611 Platelet activation - Homo sapiens (human) (24)

hsa:60 ACTB; actin, beta hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:54518 APBB1IP; amyloid beta precursor protein binding family B member 1 interacting protein hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:83706 FERMT3; fermitin family member 3 hsa:2243 FGA; fibrinogen alpha chain hsa:2244 FGB; fibrinogen beta chain hsa:2266 FGG; fibrinogen gamma chain hsa:2814 GP5; glycoprotein V platelet hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3690 ITGB3; integrin subunit beta 3 hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:8773 SNAP23; synaptosome associated protein 23kDa hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7094 TLN1; talin 1 hsa:7408 VASP; vasodilator-stimulated phosphoprotein hsa:7450 VWF; von Willebrand factor

hsa05230 Central carbon metabolism in cancer - Homo sapiens (human) (24)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:5979 RET; ret proto-oncogene (EC:2.7.10.1) hsa:9123 SLC16A3; solute carrier family 16 member 3 hsa:6510 SLC1A5; solute carrier family 1 member 5 hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6514 SLC2A2; solute carrier family 2 member 2 hsa:8140 SLC7A5; solute carrier family 7 member 5 hsa:7157 TP53; tumor protein p53

hsa01522 Endocrine resistance - Homo sapiens (human) (24)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:8202 NCOA3; nuclear receptor coactivator 3 (EC:2.3.1.48) hsa:4851 NOTCH1; notch 1 hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7157 TP53; tumor protein p53

hsa05212 Pancreatic cancer - Homo sapiens (human) (23)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6 hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:998 CDC42; cell division cycle 42 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05143 African trypanosomiasis - Homo sapiens (human) (23)

hsa:335 APOA1; apolipoprotein A1 hsa:8542 APOL1; apolipoprotein L1 hsa:2150 F2RL1; F2R like trypsin receptor 1 hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:3039 HBA1; hemoglobin subunit alpha 1 hsa:3040 HBA2; hemoglobin subunit alpha 2 hsa:3043 HBB; hemoglobin subunit beta hsa:3250 HPR; haptoglobin-related protein hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3620 IDO1; indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52) hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3606 IL18; interleukin 18 hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:3910 LAMA4; laminin subunit alpha 4 hsa:4615 MYD88; myeloid differentiation primary response 88 hsa:54106 TLR9; toll like receptor 9 hsa:7124 TNF; tumor necrosis factor hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa04722 Neurotrophin signaling pathway - Homo sapiens (human) (23)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:397 ARHGDIB; Rho GDP dissociation inhibitor beta hsa:468 ATF4; activating transcription factor 4 hsa:998 CDC42; cell division cycle 42 hsa:356 FASLG; Fas ligand hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:51135 IRAK4; interleukin 1 receptor associated kinase 4 (EC:2.7.11.1) hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6464 SHC1; SHC adaptor protein 1 hsa:7157 TP53; tumor protein p53 hsa:7189 TRAF6; TNF receptor associated factor 6

hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human) (23)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:558 AXL; AXL receptor tyrosine kinase (EC:2.7.10.1) hsa:10018 BCL2L11; BCL2 like 11 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2247 FGF2; fibroblast growth factor 2 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3569 IL6; interleukin 6 hsa:3570 IL6R; interleukin 6 receptor hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:3084 NRG1; neuregulin 1 hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05222 Small cell lung cancer - Homo sapiens (human) (23)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:54205 CYCS; cytochrome c, somatic hsa:2335 FN1; fibronectin 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3685 ITGAV; integrin subunit alpha V hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:7157 TP53; tumor protein p53 hsa:7185 TRAF1; TNF receptor associated factor 1 hsa:7188 TRAF5; TNF receptor associated factor 5 hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human) (23)

hsa:468 ATF4; activating transcription factor 4 hsa:80331 DNAJC5; DnaJ heat shock protein family (Hsp40) member C5 hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:10961 ERP29; endoplasmic reticulum protein 29 hsa:26270 FBXO6; F-box protein 6 hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:22824 HSPA4L; heat shock protein family A (Hsp70) member 4 like hsa:3309 HSPA5; heat shock protein family A (Hsp70) member 5 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:5034 P4HB; prolyl 4-hydroxylase subunit beta (EC:5.3.4.1) hsa:10802 SEC24A; SEC24 homolog A, COPII coat complex component hsa:25956 SEC31B; SEC31 homolog B, COPII coat complex component hsa:6745 SSR1; signal sequence receptor subunit 1 hsa:6747 SSR3; signal sequence receptor subunit 3 hsa:201595 STT3B; STT3B, catalytic subunit of the oligosaccharyltransferase complex (EC:2.4.99.18) hsa:84447 SYVN1; synoviolin 1 (EC:6.3.2.-) hsa:23471 TRAM1; translocation associated membrane protein 1

hsa05020 Prion diseases - Homo sapiens (human) (22)

hsa:712 C1QA; complement component 1, q subcomponent, A chain hsa:713 C1QB; complement component 1, q subcomponent, B chain hsa:714 C1QC; complement component 1, q subcomponent, C chain hsa:727 C5; complement component 5 hsa:729 C6; complement component 6 hsa:730 C7; complement component 7 hsa:731 C8A; complement component 8 alpha subunit hsa:732 C8B; complement component 8, beta polypeptide hsa:733 C8G; complement component 8, gamma polypeptide hsa:735 C9; complement component 9 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:1958 EGR1; early growth response 1 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3309 HSPA5; heat shock protein family A (Hsp70) member 5 hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3569 IL6; interleukin 6 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4684 NCAM1; neural cell adhesion molecule 1 (EC:2.7.11.1) hsa:4851 NOTCH1; notch 1

hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human) (22)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:998 CDC42; cell division cycle 42 hsa:1072 CFL1; cofilin 1 hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:1794 DOCK2; dedicator of cytokinesis 2 hsa:2209 FCGR1A; Fc fragment of IgG receptor Ia hsa:2214 FCGR3A; Fc fragment of IgG receptor IIIa hsa:2934 GSN; gelsolin hsa:3635 INPP5D; inositol polyphosphate-5-phosphatase D (EC:3.1.3.86) hsa:3636 INPPL1; inositol polyphosphate phosphatase like 1 (EC:3.1.3.86) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:65108 MARCKSL1; MARCKS-like 1 hsa:653361 NCF1; neutrophil cytosolic factor 1 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7408 VASP; vasodilator-stimulated phosphoprotein hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3 hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04915 Estrogen signaling pathway - Homo sapiens (human) (22)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa04917 Prolactin signaling pathway - Homo sapiens (human) (22)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1154 CISH; cytokine inducible SH2 containing protein hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3659 IRF1; interferon regulatory factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6464 SHC1; SHC adaptor protein 1 hsa:6514 SLC2A2; solute carrier family 2 member 2 hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:8835 SOCS2; suppressor of cytokine signaling 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:6772 STAT1; signal transducer and activator of transcription 1 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:8600 TNFSF11; tumor necrosis factor superfamily member 11

hsa04672 Intestinal immune network for IgA production - Homo sapiens (human) (22)

hsa:56477 CCL28; C-C motif chemokine ligand 28 hsa:940 CD28; CD28 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:6387 CXCL12; C-X-C motif chemokine ligand 12 hsa:7852 CXCR4; C-X-C motif chemokine receptor 4 hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3586 IL10; interleukin 10 hsa:3600 IL15; interleukin 15 hsa:3558 IL2; interleukin 2 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3569 IL6; interleukin 6 hsa:3676 ITGA4; integrin subunit alpha 4 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:10673 TNFSF13B; tumor necrosis factor superfamily member 13b

hsa05131 Shigellosis - Homo sapiens (human) (22)

hsa:60 ACTB; actin, beta hsa:9474 ATG5; autophagy related 5 hsa:960 CD44; CD44 molecule (Indian blood group) hsa:998 CDC42; cell division cycle 42 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:2017 CTTN; cortactin hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:64127 NOD2; nucleotide binding oligomerization domain containing 2 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7414 VCL; vinculin hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa04012 ErbB signaling pathway - Homo sapiens (human) (22)

hsa:27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:374 AREG; amphiregulin hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2069 EREG; epiregulin hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:3084 NRG1; neuregulin 1 hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa05330 Allograft rejection - Homo sapiens (human) (21)

hsa:940 CD28; CD28 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3458 IFNG; interferon, gamma hsa:3586 IL10; interleukin 10 hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3558 IL2; interleukin 2 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:7124 TNF; tumor necrosis factor

hsa04931 Insulin resistance - Homo sapiens (human) (21)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:948 CD36; CD36 molecule hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2308 FOXO1; forkhead box O1 hsa:2673 GFPT1; glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3569 IL6; interleukin 6 hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:133522 PPARGC1B; PPARG coactivator 1 beta hsa:5834 PYGB; phosphorylase, glycogen; brain (EC:2.4.1.1) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6514 SLC2A2; solute carrier family 2 member 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7124 TNF; tumor necrosis factor hsa:57761 TRIB3; tribbles pseudokinase 3

hsa04024 cAMP signaling pathway - Homo sapiens (human) (21)

hsa:135 ADORA2A; adenosine A2a receptor hsa:154 ADRB2; adrenoceptor beta 2 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4852 NPY; neuropeptide Y hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3

hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) (21)

hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86) hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:998 CDC42; cell division cycle 42 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:2919 CXCL1; C-X-C motif chemokine ligand 1 hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:3579 CXCR2; C-X-C motif chemokine receptor 2 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa04072 Phospholipase D signaling pathway - Homo sapiens (human) (21)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:3579 CXCR2; C-X-C motif chemokine receptor 2 hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107) hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:387 RHOA; ras homolog family member A hsa:6464 SHC1; SHC adaptor protein 1 hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2)

hsa05219 Bladder cancer - Homo sapiens (human) (20)

hsa:999 CDH1; cadherin 1 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:3576 CXCL8; C-X-C motif chemokine ligand 8 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:4318 MMP9; matrix metallopeptidase 9 (EC:3.4.24.35) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7057 THBS1; thrombospondin 1 hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04512 ECM-receptor interaction - Homo sapiens (human) (20)

hsa:948 CD36; CD36 molecule hsa:960 CD44; CD44 molecule (Indian blood group) hsa:961 CD47; CD47 molecule hsa:2335 FN1; fibronectin 1 hsa:2814 GP5; glycoprotein V platelet hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:3910 LAMA4; laminin subunit alpha 4 hsa:3911 LAMA5; laminin subunit alpha 5 hsa:3914 LAMB3; laminin subunit beta 3 hsa:5649 RELN; reelin hsa:6385 SDC4; syndecan 4 hsa:6696 SPP1; secreted phosphoprotein 1 hsa:7057 THBS1; thrombospondin 1 hsa:3371 TNC; tenascin C hsa:7448 VTN; vitronectin hsa:7450 VWF; von Willebrand factor

hsa04390 Hippo signaling pathway - Homo sapiens (human) (20)

hsa:60 ACTB; actin, beta hsa:374 AREG; amphiregulin hsa:650 BMP2; bone morphogenetic protein 2 hsa:652 BMP4; bone morphogenetic protein 4 hsa:654 BMP6; bone morphogenetic protein 6 hsa:999 CDH1; cadherin 1 hsa:1490 CTGF; connective tissue growth factor hsa:1499 CTNNB1; catenin beta 1 hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3397 ID1; inhibitor of DNA binding 1, HLH protein hsa:3398 ID2; inhibitor of DNA binding 2, HLH protein hsa:3689 ITGB2; integrin subunit beta 2 hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5054 SERPINE1; serpin family E member 1 hsa:4092 SMAD7; SMAD family member 7 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7474 WNT5A; Wnt family member 5A hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa04150 mTOR signaling pathway - Homo sapiens (human) (20)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:54541 DDIT4; DNA damage inducible transcript 4 hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:387 RHOA; ras homolog family member A hsa:83667 SESN2; sestrin 2 hsa:6446 SGK1; serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) hsa:6520 SLC3A2; solute carrier family 3 member 2 hsa:8140 SLC7A5; solute carrier family 7 member 5 hsa:7124 TNF; tumor necrosis factor hsa:7474 WNT5A; Wnt family member 5A

hsa04071 Sphingolipid signaling pathway - Homo sapiens (human) (20)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:624 BDKRB2; bradykinin receptor B2 hsa:204219 CERS3; ceramide synthase 3 (EC:2.3.1.24) hsa:1509 CTSD; cathepsin D (EC:3.4.23.5) hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:81537 SGPP1; sphingosine-1-phosphate phosphatase 1 hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2 (EC:2.3.1.50) hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa04910 Insulin signaling pathway - Homo sapiens (human) (20)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:2308 FOXO1; forkhead box O1 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:3636 INPPL1; inositol polyphosphate phosphatase like 1 (EC:3.1.3.86) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2872 MKNK2; MAP kinase interacting serine/threonine kinase 2 (EC:2.7.11.1) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:5834 PYGB; phosphorylase, glycogen; brain (EC:2.4.1.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:8835 SOCS2; suppressor of cytokine signaling 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3

hsa04940 Type I diabetes mellitus - Homo sapiens (human) (20)

hsa:940 CD28; CD28 molecule hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3329 HSPD1; heat shock protein family D (Hsp60) member 1 hsa:3458 IFNG; interferon, gamma hsa:3592 IL12A; interleukin 12A hsa:3593 IL12B; interleukin 12B hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3558 IL2; interleukin 2 hsa:4049 LTA; lymphotoxin alpha hsa:7124 TNF; tumor necrosis factor

hsa04350 TGF-beta signaling pathway - Homo sapiens (human) (20)

hsa:650 BMP2; bone morphogenetic protein 2 hsa:652 BMP4; bone morphogenetic protein 4 hsa:654 BMP6; bone morphogenetic protein 6 hsa:10468 FST; follistatin hsa:3397 ID1; inhibitor of DNA binding 1, HLH protein hsa:3398 ID2; inhibitor of DNA binding 2, HLH protein hsa:3399 ID3; inhibitor of DNA binding 3, HLH protein hsa:3458 IFNG; interferon, gamma hsa:3624 INHBA; inhibin beta A hsa:3625 INHBB; inhibin beta B hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5933 RBL1; retinoblastoma-like 1 hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:4092 SMAD7; SMAD family member 7 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7057 THBS1; thrombospondin 1 hsa:7124 TNF; tumor necrosis factor

hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human) (20)

hsa:103 ADAR; adenosine deaminase, RNA-specific (EC:3.5.4.37) hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:6351 CCL4; C-C motif chemokine ligand 4 hsa:6352 CCL5; C-C motif chemokine ligand 5 hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3627 CXCL10; C-X-C motif chemokine ligand 10 hsa:23586 DDX58; DEXD/H-box helicase 58 (EC:3.6.4.13) hsa:3456 IFNB1; interferon beta 1 hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3606 IL18; interleukin 18 hsa:3553 IL1B; interleukin 1 beta hsa:90865 IL33; interleukin 33 hsa:3569 IL6; interleukin 6 hsa:3665 IRF7; interferon regulatory factor 7 hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:81030 ZBP1; Z-DNA binding protein 1

hsa04115 p53 signaling pathway - Homo sapiens (human) (19)

hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:901 CCNG2; cyclin G2 hsa:3732 CD82; CD82 molecule hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:54205 CYCS; cytochrome c, somatic hsa:355 FAS; Fas cell surface death receptor hsa:1647 GADD45A; growth arrest and DNA damage inducible alpha hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:10912 GADD45G; growth arrest and DNA damage inducible gamma hsa:3479 IGF1; insulin like growth factor 1 hsa:4193 MDM2; MDM2 proto-oncogene hsa:5054 SERPINE1; serpin family E member 1 hsa:27244 SESN1; sestrin 1 hsa:83667 SESN2; sestrin 2 hsa:7057 THBS1; thrombospondin 1 hsa:7157 TP53; tumor protein p53

hsa05416 Viral myocarditis - Homo sapiens (human) (19)

hsa:27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:60 ACTB; actin, beta hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:940 CD28; CD28 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:54205 CYCS; cytochrome c, somatic hsa:1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3689 ITGB2; integrin subunit beta 2

hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human) (19)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:1437 CSF2; colony stimulating factor 2 hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3596 IL13; interleukin 13 hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:3635 INPP5D; inositol polyphosphate-5-phosphatase D (EC:3.1.3.86) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:6850 SYK; spleen tyrosine kinase (EC:2.7.10.2) hsa:7124 TNF; tumor necrosis factor hsa:7409 VAV1; vav guanine nucleotide exchange factor 1 hsa:10451 VAV3; vav guanine nucleotide exchange factor 3

hsa05220 Chronic myeloid leukemia - Homo sapiens (human) (18)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6464 SHC1; SHC adaptor protein 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7157 TP53; tumor protein p53

hsa04612 Antigen processing and presentation - Homo sapiens (human) (18)

hsa:920 CD4; CD4 molecule hsa:972 CD74; CD74 molecule hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3309 HSPA5; heat shock protein family A (Hsp70) member 5 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3458 IFNG; interferon, gamma hsa:6890 TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) hsa:7124 TNF; tumor necrosis factor

hsa04921 Oxytocin signaling pathway - Homo sapiens (human) (18)

hsa:60 ACTB; actin, beta hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1938 EEF2; eukaryotic translation elongation factor 2 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4208 MEF2C; myocyte enhancer factor 2C hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:1827 RCAN1; regulator of calcineurin 1 hsa:5997 RGS2; regulator of G-protein signaling 2 hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human) (18)

hsa:60 ACTB; actin, beta hsa:9181 ARHGEF2; Rho/Rac guanine nucleotide exchange factor 2 hsa:929 CD14; CD14 molecule hsa:998 CDC42; cell division cycle 42 hsa:999 CDH1; cadherin 1 hsa:1499 CTNNB1; catenin beta 1 hsa:2017 CTTN; cortactin hsa:4691 NCL; nucleolin hsa:100506658 OCLN; occludin (EC:2.1.1.67) hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:7099 TLR4; toll like receptor 4 hsa:7277 TUBA4A; tubulin alpha 4a hsa:203068 TUBB; tubulin beta class I hsa:84617 TUBB6; tubulin beta 6 class V hsa:8976 WASL; Wiskott-Aldrich syndrome like hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa05320 Autoimmune thyroid disease - Homo sapiens (human) (18)

hsa:940 CD28; CD28 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:1493 CTLA4; cytotoxic T-lymphocyte associated protein 4 hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3586 IL10; interleukin 10 hsa:3558 IL2; interleukin 2 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5

hsa04920 Adipocytokine signaling pathway - Homo sapiens (human) (17)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:948 CD36; CD36 molecule hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3952 LEP; leptin hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:4792 NFKBIA; NFKB inhibitor alpha hsa:4793 NFKBIB; NFKB inhibitor beta hsa:4852 NPY; neuropeptide Y hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:6774 STAT3; signal transducer and activator of transcription 3 hsa:7124 TNF; tumor necrosis factor

hsa05010 Alzheimer's disease - Homo sapiens (human) (17)

hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86) hsa:348 APOE; apolipoprotein E hsa:351 APP; amyloid beta precursor protein hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.1) hsa:54205 CYCS; cytochrome c, somatic hsa:355 FAS; Fas cell surface death receptor hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3553 IL1B; interleukin 1 beta hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:7124 TNF; tumor necrosis factor hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa05332 Graft-versus-host disease - Homo sapiens (human) (17)

hsa:940 CD28; CD28 molecule hsa:941 CD80; CD80 molecule hsa:942 CD86; CD86 molecule hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:3002 GZMB; granzyme B (EC:3.4.21.79) hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3458 IFNG; interferon, gamma hsa:3552 IL1A; interleukin 1 alpha hsa:3553 IL1B; interleukin 1 beta hsa:3558 IL2; interleukin 2 hsa:3569 IL6; interleukin 6 hsa:7124 TNF; tumor necrosis factor

hsa05210 Colorectal cancer - Homo sapiens (human) (17)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1499 CTNNB1; catenin beta 1 hsa:54205 CYCS; cytochrome c, somatic hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:387 RHOA; ras homolog family member A hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7157 TP53; tumor protein p53

hsa04520 Adherens junction - Homo sapiens (human) (16)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:998 CDC42; cell division cycle 42 hsa:999 CDH1; cadherin 1 hsa:1499 CTNNB1; catenin beta 1 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:4008 LMO7; LIM domain 7 (EC:3.4.19.12) hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:387 RHOA; ras homolog family member A hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7414 VCL; vinculin hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa05221 Acute myeloid leukemia - Homo sapiens (human) (16)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1050 CEBPA; CCAAT/enhancer binding protein alpha hsa:1147 CHUK; conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:3728 JUP; junction plakoglobin hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:6774 STAT3; signal transducer and activator of transcription 3

hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human) (15)

hsa:154 ADRB2; adrenoceptor beta 2 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:624 BDKRB2; bradykinin receptor B2 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4208 MEF2C; myocyte enhancer factor 2C hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:5997 RGS2; regulator of G-protein signaling 2 hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1) hsa:6722 SRF; serum response factor hsa:7408 VASP; vasodilator-stimulated phosphoprotein

hsa05231 Choline metabolism in cancer - Homo sapiens (human) (15)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:5900 RALGDS; ral guanine nucleotide dissociation stimulator hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa05310 Asthma - Homo sapiens (human) (15)

hsa:6356 CCL11; C-C motif chemokine ligand 11 hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:2207 FCER1G; Fc fragment of IgE receptor Ig hsa:3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1 hsa:105369230 HLA-DRB1; HLA class II histocompatibility antigen, DRB1-7 beta chain hsa:3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3 hsa:3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4 hsa:3586 IL10; interleukin 10 hsa:3596 IL13; interleukin 13 hsa:3562 IL3; interleukin 3 hsa:3565 IL4; interleukin 4 hsa:3567 IL5; interleukin 5 hsa:7124 TNF; tumor necrosis factor

hsa01524 Platinum drug resistance - Homo sapiens (human) (15)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:54205 CYCS; cytochrome c, somatic hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:355 FAS; Fas cell surface death receptor hsa:356 FASLG; Fas ligand hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:7155 TOP2B; topoisomerase (DNA) II beta (EC:5.99.1.3) hsa:7157 TP53; tumor protein p53 hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human) (15)

hsa:60 ACTB; actin, beta hsa:23607 CD2AP; CD2-associated protein hsa:998 CDC42; cell division cycle 42 hsa:999 CDH1; cadherin 1 hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1499 CTNNB1; catenin beta 1 hsa:2017 CTTN; cortactin hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:2335 FN1; fibronectin 1 hsa:387 RHOA; ras homolog family member A hsa:6464 SHC1; SHC adaptor protein 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7414 VCL; vinculin hsa:8976 WASL; Wiskott-Aldrich syndrome like

hsa05218 Melanoma - Homo sapiens (human) (15)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:999 CDH1; cadherin 1 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2247 FGF2; fibroblast growth factor 2 hsa:3082 HGF; hepatocyte growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:7157 TP53; tumor protein p53

hsa04310 Wnt signaling pathway - Homo sapiens (human) (14)

hsa:1499 CTNNB1; catenin beta 1 hsa:27123 DKK2; dickkopf WNT signaling pathway inhibitor 2 hsa:8061 FOSL1; FOS like 1, AP-1 trancription factor subunit hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:387 RHOA; ras homolog family member A hsa:5176 SERPINF1; serpin family F member 1 hsa:7157 TP53; tumor protein p53 hsa:7474 WNT5A; Wnt family member 5A

hsa04530 Tight junction - Homo sapiens (human) (14)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:998 CDC42; cell division cycle 42 hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1499 CTNNB1; catenin beta 1 hsa:2017 CTTN; cortactin hsa:2037 EPB41L2; erythrocyte membrane protein band 4.1 like 2 hsa:11336 EXOC3; exocyst complex component 3 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:4301 MLLT4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 hsa:100506658 OCLN; occludin (EC:2.1.1.67) hsa:387 RHOA; ras homolog family member A hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human) (14)

hsa:60 ACTB; actin, beta hsa:87 ACTN1; actinin alpha 1 hsa:1000 CDH2; cadherin 2 hsa:1499 CTNNB1; catenin beta 1 hsa:1829 DSG2; desmoglein 2 hsa:1832 DSP; desmoplakin hsa:2697 GJA1; gap junction protein alpha 1 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:3728 JUP; junction plakoglobin hsa:4000 LMNA; lamin A/C

hsa04110 Cell cycle - Homo sapiens (human) (14)

hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:9700 ESPL1; extra spindle pole bodies like 1, separase (EC:3.4.22.49) hsa:1647 GADD45A; growth arrest and DNA damage inducible alpha hsa:4616 GADD45B; growth arrest and DNA damage inducible beta hsa:10912 GADD45G; growth arrest and DNA damage inducible gamma hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:4193 MDM2; MDM2 proto-oncogene hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5933 RBL1; retinoblastoma-like 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7157 TP53; tumor protein p53 hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa04211 Longevity regulating pathway - Homo sapiens (human) (14)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:9474 ATG5; autophagy related 5 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:2308 FOXO1; forkhead box O1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit hsa:27244 SESN1; sestrin 1 hsa:83667 SESN2; sestrin 2 hsa:7157 TP53; tumor protein p53

hsa05211 Renal cell carcinoma - Homo sapiens (human) (14)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:998 CDC42; cell division cycle 42 hsa:112399 EGLN3; egl-9 family hypoxia inducible factor 3 (EC:1.14.11.29) hsa:3082 HGF; hepatocyte growth factor hsa:3091 HIF1A; hypoxia inducible factor 1 alpha subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5058 PAK1; p21 (RAC1) activated kinase 1 (EC:2.7.11.1) hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05214 Glioma - Homo sapiens (human) (14)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4193 MDM2; MDM2 proto-oncogene hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:6464 SHC1; SHC adaptor protein 1 hsa:7157 TP53; tumor protein p53

hsa05213 Endometrial cancer - Homo sapiens (human) (14)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:999 CDH1; cadherin 1 hsa:1499 CTNNB1; catenin beta 1 hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:7157 TP53; tumor protein p53

hsa04912 GnRH signaling pathway - Homo sapiens (human) (14)

hsa:468 ATF4; activating transcription factor 4 hsa:998 CDC42; cell division cycle 42 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:1839 HBEGF; heparin binding EGF like growth factor hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:10746 MAP3K2; mitogen-activated protein kinase kinase kinase 2 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:4313 MMP2; matrix metallopeptidase 2 (EC:3.4.24.24) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human) (13)

hsa:135 ADORA2A; adenosine A2a receptor hsa:136 ADORA2B; adenosine A2b receptor hsa:154 ADRB2; adrenoceptor beta 2 hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:1511 CTSG; cathepsin G (EC:3.4.21.20) hsa:2147 F2; coagulation factor II, thrombin (EC:3.4.21.5) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:2150 F2RL1; F2R like trypsin receptor 1 hsa:2859 GPR35; G protein-coupled receptor 35 hsa:3952 LEP; leptin hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5029 P2RY2; purinergic receptor P2Y2

hsa04540 Gap junction - Homo sapiens (human) (13)

hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2697 GJA1; gap junction protein alpha 1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:1902 LPAR1; lysophosphatidic acid receptor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:10746 MAP3K2; mitogen-activated protein kinase kinase kinase 2 (EC:2.7.11.25) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7277 TUBA4A; tubulin alpha 4a hsa:203068 TUBB; tubulin beta class I hsa:84617 TUBB6; tubulin beta 6 class V

hsa04142 Lysosome - Homo sapiens (human) (13)

hsa:54 ACP5; acid phosphatase 5, tartrate resistant (EC:3.1.3.2) hsa:8943 AP3D1; adaptor related protein complex 3 delta 1 subunit hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:968 CD68; CD68 molecule hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1509 CTSD; cathepsin D (EC:3.4.23.5) hsa:1511 CTSG; cathepsin G (EC:3.4.21.20) hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31) hsa:3916 LAMP1; lysosomal associated membrane protein 1 hsa:27074 LAMP3; lysosomal associated membrane protein 3 hsa:57192 MCOLN1; mucolipin 1 hsa:6556 SLC11A1; solute carrier family 11 member 1

hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human) (13)

hsa:60 ACTB; actin, beta hsa:70 ACTC1; actin, alpha, cardiac muscle 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3569 IL6; interleukin 6 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:4000 LMNA; lamin A/C hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7170 TPM3; tropomyosin 3

hsa05414 Dilated cardiomyopathy - Homo sapiens (human) (12)

hsa:60 ACTB; actin, beta hsa:70 ACTC1; actin, alpha, cardiac muscle 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3674 ITGA2B; integrin subunit alpha 2b hsa:3676 ITGA4; integrin subunit alpha 4 hsa:3685 ITGAV; integrin subunit alpha V hsa:3690 ITGB3; integrin subunit beta 3 hsa:3693 ITGB5; integrin subunit beta 5 hsa:4000 LMNA; lamin A/C hsa:7040 TGFB1; transforming growth factor beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7170 TPM3; tropomyosin 3

hsa04152 AMPK signaling pathway - Homo sapiens (human) (12)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:948 CD36; CD36 molecule hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1938 EEF2; eukaryotic translation elongation factor 2 hsa:2308 FOXO1; forkhead box O1 hsa:3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) hsa:3479 IGF1; insulin like growth factor 1 hsa:3952 LEP; leptin hsa:6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7 (EC:2.7.11.25) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11)

hsa05016 Huntington's disease - Homo sapiens (human) (12)

hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:54205 CYCS; cytochrome c, somatic hsa:7052 TGM2; transglutaminase 2 (EC:2.3.2.13) hsa:7157 TP53; tumor protein p53 hsa:7350 UCP1; uncoupling protein 1 hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa03320 PPAR signaling pathway - Homo sapiens (human) (12)

hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:51129 ANGPTL4; angiopoietin like 4 hsa:335 APOA1; apolipoprotein A1 hsa:336 APOA2; apolipoprotein A2 hsa:116519 APOA5; apolipoprotein A5 hsa:345 APOC3; apolipoprotein C3 hsa:948 CD36; CD36 molecule hsa:2168 FABP1; fatty acid binding protein 1 hsa:2170 FABP3; fatty acid binding protein 3 hsa:2167 FABP4; fatty acid binding protein 4 hsa:4973 OLR1; oxidized low density lipoprotein receptor 1 hsa:7350 UCP1; uncoupling protein 1

hsa01200 Carbon metabolism - Homo sapiens (human) (12)

hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3) hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52) hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa05034 Alcoholism - Homo sapiens (human) (12)

hsa:135 ADORA2A; adenosine A2a receptor hsa:136 ADORA2B; adenosine A2b receptor hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:85235 HIST1H2AH; histone cluster 1, H2ah hsa:85236 HIST1H2BK; histone cluster 1, H2bk hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4852 NPY; neuropeptide Y hsa:6464 SHC1; SHC adaptor protein 1

hsa04930 Type II diabetes mellitus - Homo sapiens (human) (12)

hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1) hsa:6514 SLC2A2; solute carrier family 2 member 2 hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:8835 SOCS2; suppressor of cytokine signaling 2 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:7124 TNF; tumor necrosis factor

hsa04370 VEGF signaling pathway - Homo sapiens (human) (12)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:998 CDC42; cell division cycle 42 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4773 NFATC2; nuclear factor of activated T-cells 2 hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2) hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04020 Calcium signaling pathway - Homo sapiens (human) (11)

hsa:135 ADORA2A; adenosine A2a receptor hsa:136 ADORA2B; adenosine A2b receptor hsa:154 ADRB2; adrenoceptor beta 2 hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:2149 F2R; coagulation factor II thrombin receptor hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91)

hsa04916 Melanogenesis - Homo sapiens (human) (11)

hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1499 CTNNB1; catenin beta 1 hsa:1906 EDN1; endothelin 1 hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3815 KIT; KIT proto-oncogene receptor tyrosine kinase (EC:2.7.10.1) hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:7474 WNT5A; Wnt family member 5A

hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human) (11)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:9474 ATG5; autophagy related 5 hsa:2308 FOXO1; forkhead box O1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:3479 IGF1; insulin like growth factor 1 hsa:2475 MTOR; mechanistic target of rapamycin (EC:2.7.11.1)

hsa05223 Non-small cell lung cancer - Homo sapiens (human) (11)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:1019 CDK4; cyclin-dependent kinase 4 (EC:2.7.11.22) hsa:1950 EGF; epidermal growth factor hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:7157 TP53; tumor protein p53

hsa01230 Biosynthesis of amino acids - Homo sapiens (human) (10)

hsa:1491 CTH; cystathionine gamma-lyase (EC:4.4.1.1) hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3) hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52) hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human) (10)

hsa:70 ACTC1; actin, alpha, cardiac muscle 1 hsa:154 ADRB2; adrenoceptor beta 2 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1390 CREM; cAMP responsive element modulator hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:7170 TPM3; tropomyosin 3

hsa05216 Thyroid cancer - Homo sapiens (human) (10)

hsa:999 CDH1; cadherin 1 hsa:1499 CTNNB1; catenin beta 1 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4609 MYC; v-myc avian myelocytomatosis viral oncogene homolog hsa:5979 RET; ret proto-oncogene (EC:2.7.10.1) hsa:7157 TP53; tumor protein p53 hsa:7170 TPM3; tropomyosin 3

hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human) (10)

hsa:623 BDKRB1; bradykinin receptor B1 hsa:624 BDKRB2; bradykinin receptor B2 hsa:2150 F2RL1; F2R like trypsin receptor 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:3553 IL1B; interleukin 1 beta hsa:3556 IL1RAP; interleukin 1 receptor accessory protein hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:5029 P2RY2; purinergic receptor P2Y2 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa04922 Glucagon signaling pathway - Homo sapiens (human) (9)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2308 FOXO1; forkhead box O1 hsa:2641 GCG; glucagon hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27) hsa:5834 PYGB; phosphorylase, glycogen; brain (EC:2.4.1.1) hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6514 SLC2A2; solute carrier family 2 member 2

hsa04970 Salivary secretion - Homo sapiens (human) (9)

hsa:154 ADRB2; adrenoceptor beta 2 hsa:820 CAMP; cathelicidin antimicrobial peptide hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:1755 DMBT1; deleted in malignant brain tumors 1 hsa:3346 HTN1; histatin 1 hsa:3347 HTN3; histatin 3 hsa:4069 LYZ; lysozyme (EC:3.2.1.17) hsa:4589 MUC7; mucin 7, secreted hsa:6779 STATH; statherin

hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human) (9)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 hsa:3326 HSP90AB1; heat shock protein 90kDa alpha family class B member 1 hsa:3479 IGF1; insulin like growth factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)

hsa04270 Vascular smooth muscle contraction - Homo sapiens (human) (9)

hsa:135 ADORA2A; adenosine A2a receptor hsa:136 ADORA2B; adenosine A2b receptor hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4) hsa:10268 RAMP3; receptor (G protein-coupled) activity modifying protein 3 hsa:387 RHOA; ras homolog family member A hsa:6093 ROCK1; Rho associated coiled-coil containing protein kinase 1 (EC:2.7.11.1)

hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human) (9)

hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa04726 Serotonergic synapse - Homo sapiens (human) (9)

hsa:246 ALOX15; arachidonate 15-lipoxygenase (EC:1.13.11.31 1.13.11.33) hsa:240 ALOX5; arachidonate 5-lipoxygenase (EC:1.13.11.34) hsa:351 APP; amyloid beta precursor protein hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:1843 DUSP1; dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa03013 RNA transport - Homo sapiens (human) (8)

hsa:1915 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 hsa:8662 EIF3B; eukaryotic translation initiation factor 3 subunit B hsa:8665 EIF3F; eukaryotic translation initiation factor 3 subunit F (EC:3.4.19.12) hsa:1973 EIF4A1; eukaryotic translation initiation factor 4A1 (EC:3.6.4.13) hsa:1977 EIF4E; eukaryotic translation initiation factor 4E hsa:1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 hsa:4686 NCBP1; nuclear cap binding protein subunit 1 hsa:8761 PABPC4; poly(A) binding protein cytoplasmic 4

hsa04114 Oocyte meiosis - Homo sapiens (human) (8)

hsa:80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 hsa:9700 ESPL1; extra spindle pole bodies like 1, separase (EC:3.4.22.49) hsa:3479 IGF1; insulin like growth factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human) (8)

hsa:4193 MDM2; MDM2 proto-oncogene hsa:4281 MID1; midline 1 hsa:8651 SOCS1; suppressor of cytokine signaling 1 hsa:9021 SOCS3; suppressor of cytokine signaling 3 hsa:84447 SYVN1; synoviolin 1 (EC:6.3.2.-) hsa:7189 TRAF6; TNF receptor associated factor 6 hsa:9246 UBE2L6; ubiquitin conjugating enzyme E2 L6 (EC:2.3.2.23) hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa04725 Cholinergic synapse - Homo sapiens (human) (8)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa05012 Parkinson's disease - Homo sapiens (human) (7)

hsa:135 ADORA2A; adenosine A2a receptor hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:54205 CYCS; cytochrome c, somatic hsa:9246 UBE2L6; ubiquitin conjugating enzyme E2 L6 (EC:2.3.2.23) hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa04320 Dorso-ventral axis formation - Homo sapiens (human) (7)

hsa:80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 hsa:1956 EGFR; epidermal growth factor receptor (EC:2.7.10.1) hsa:2114 ETS2; ETS proto-oncogene 2, transcription factor hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:4851 NOTCH1; notch 1

hsa03018 RNA degradation - Homo sapiens (human) (7)

hsa:2023 ENO1; enolase 1 (EC:4.2.1.11) hsa:2026 ENO2; enolase 2 (EC:4.2.1.11) hsa:3313 HSPA9; heat shock protein family A (Hsp70) member 9 hsa:3329 HSPD1; heat shock protein family D (Hsp60) member 1 hsa:8761 PABPC4; poly(A) binding protein cytoplasmic 4 hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:54464 XRN1; 5'-3' exoribonuclease 1

hsa03010 Ribosome - Homo sapiens (human) (7)

hsa:29088 MRPL15; mitochondrial ribosomal protein L15 hsa:219927 MRPL21; mitochondrial ribosomal protein L21 hsa:29093 MRPL22; mitochondrial ribosomal protein L22 hsa:6150 MRPL23; mitochondrial ribosomal protein L23 hsa:64983 MRPL32; mitochondrial ribosomal protein L32 hsa:54460 MRPS21; mitochondrial ribosomal protein S21 hsa:6132 RPL8; ribosomal protein L8

hsa04975 Fat digestion and absorption - Homo sapiens (human) (7)

hsa:19 ABCA1; ATP binding cassette subfamily A member 1 hsa:335 APOA1; apolipoprotein A1 hsa:337 APOA4; apolipoprotein A4 hsa:338 APOB; apolipoprotein B hsa:948 CD36; CD36 molecule hsa:2168 FABP1; fatty acid binding protein 1 hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4)

hsa04215 Apoptosis - multiple species - Homo sapiens (human) (7)

hsa:10018 BCL2L11; BCL2 like 11 hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:841 CASP8; caspase 8 (EC:3.4.22.61) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:54205 CYCS; cytochrome c, somatic hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24) hsa:331 XIAP; X-linked inhibitor of apoptosis

hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human) (7)

hsa:834 CASP1; caspase 1 (EC:3.4.22.36) hsa:836 CASP3; caspase 3 (EC:3.4.22.56) hsa:842 CASP9; caspase 9 (EC:3.4.22.62) hsa:54205 CYCS; cytochrome c, somatic hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa04728 Dopaminergic synapse - Homo sapiens (human) (7)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)

hsa05217 Basal cell carcinoma - Homo sapiens (human) (7)

hsa:650 BMP2; bone morphogenetic protein 2 hsa:652 BMP4; bone morphogenetic protein 4 hsa:1499 CTNNB1; catenin beta 1 hsa:8325 FZD8; frizzled class receptor 8 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7157 TP53; tumor protein p53 hsa:7474 WNT5A; Wnt family member 5A

hsa04721 Synaptic vesicle cycle - Homo sapiens (human) (7)

hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:8775 NAPA; NSF attachment protein alpha hsa:5864 RAB3A; RAB3A, member RAS oncogene family hsa:23025 UNC13A; unc-13 homolog A (C. elegans)

hsa04974 Protein digestion and absorption - Homo sapiens (human) (6)

hsa:7373 COL14A1; collagen type XIV alpha 1 hsa:80781 COL18A1; collagen type XVIII alpha 1 hsa:1294 COL7A1; collagen type VII alpha 1 hsa:1361 CPB2; carboxypeptidase B2 (EC:3.4.17.20) hsa:6510 SLC1A5; solute carrier family 1 member 5 hsa:6520 SLC3A2; solute carrier family 3 member 2

hsa00051 Fructose and mannose metabolism - Homo sapiens (human) (6)

hsa:57016 AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa00330 Arginine and proline metabolism - Homo sapiens (human) (6)

hsa:84735 CNDP1; carnosine dipeptidase 1 (metallopeptidase M20 family) (EC:3.4.13.20) hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1) hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39) hsa:4953 ODC1; ornithine decarboxylase 1 (EC:4.1.1.17) hsa:8974 P4HA2; prolyl 4-hydroxylase subunit alpha 2 (EC:1.14.11.2) hsa:54498 SMOX; spermine oxidase (EC:1.5.3.16)

hsa04978 Mineral absorption - Homo sapiens (human) (6)

hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3) hsa:4495 MT1G; metallothionein 1G hsa:4496 MT1H; metallothionein 1H hsa:4502 MT2A; metallothionein 2A hsa:6556 SLC11A1; solute carrier family 11 member 1 hsa:7018 TF; transferrin

hsa05340 Primary immunodeficiency - Homo sapiens (human) (6)

hsa:695 BTK; Bruton tyrosine kinase (EC:2.7.10.2) hsa:920 CD4; CD4 molecule hsa:958 CD40; CD40 molecule hsa:959 CD40LG; CD40 ligand hsa:8517 IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma hsa:6890 TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human) (6)

hsa:8773 SNAP23; synaptosome associated protein 23kDa hsa:8676 STX11; syntaxin 11 hsa:55014 STX17; syntaxin 17 hsa:6810 STX4; syntaxin 4 hsa:9341 VAMP3; vesicle associated membrane protein 3 hsa:8674 VAMP4; vesicle associated membrane protein 4

hsa03040 Spliceosome - Homo sapiens (human) (6)

hsa:3303 HSPA1A; heat shock protein family A (Hsp70) member 1A hsa:3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like hsa:3306 HSPA2; heat shock protein family A (Hsp70) member 2 hsa:3310 HSPA6; heat shock protein family A (Hsp70) member 6 hsa:3312 HSPA8; heat shock protein family A (Hsp70) member 8 hsa:4686 NCBP1; nuclear cap binding protein subunit 1

hsa05030 Cocaine addiction - Homo sapiens (human) (6)

hsa:468 ATF4; activating transcription factor 4 hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.1) hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit hsa:4790 NFKB1; nuclear factor kappa B subunit 1 hsa:5970 RELA; RELA proto-oncogene, NF-kB subunit

hsa04911 Insulin secretion - Homo sapiens (human) (6)

hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2641 GCG; glucagon hsa:5864 RAB3A; RAB3A, member RAS oncogene family hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6514 SLC2A2; solute carrier family 2 member 2

hsa00500 Starch and sucrose metabolism - Homo sapiens (human) (5)

hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:283209 PGM2L1; phosphoglucomutase 2-like 1 (EC:2.7.1.106) hsa:5834 PYGB; phosphorylase, glycogen; brain (EC:2.4.1.1)

hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human) (5)

hsa:1356 CP; ceruloplasmin (ferroxidase) (EC:1.16.3.1) hsa:1371 CPOX; coproporphyrinogen oxidase (EC:1.3.3.3) hsa:2058 EPRS; glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31) hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3)

hsa00590 Arachidonic acid metabolism - Homo sapiens (human) (5)

hsa:246 ALOX15; arachidonate 15-lipoxygenase (EC:1.13.11.31 1.13.11.33) hsa:240 ALOX5; arachidonate 5-lipoxygenase (EC:1.13.11.34) hsa:2878 GPX3; glutathione peroxidase 3 (EC:1.11.1.9) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4) hsa:9536 PTGES; prostaglandin E synthase (EC:5.3.99.3)

hsa02010 ABC transporters - Homo sapiens (human) (5)

hsa:19 ABCA1; ATP binding cassette subfamily A member 1 hsa:8714 ABCC3; ATP binding cassette subfamily C member 3 hsa:225 ABCD2; ATP binding cassette subfamily D member 2 hsa:9619 ABCG1; ATP binding cassette subfamily G member 1 hsa:6890 TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

hsa05031 Amphetamine addiction - Homo sapiens (human) (5)

hsa:23237 ARC; activity-regulated cytoskeleton-associated protein hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit

hsa04720 Long-term potentiation - Homo sapiens (human) (5)

hsa:468 ATF4; activating transcription factor 4 hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa00562 Inositol phosphate metabolism - Homo sapiens (human) (5)

hsa:3635 INPP5D; inositol polyphosphate-5-phosphatase D (EC:3.1.3.86) hsa:3636 INPPL1; inositol polyphosphate phosphatase like 1 (EC:3.1.3.86) hsa:51477 ISYNA1; inositol-3-phosphate synthase 1 (EC:5.5.1.4) hsa:9108 MTMR7; myotubularin related protein 7 (EC:3.1.3.-) hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa04730 Long-term depression - Homo sapiens (human) (5)

hsa:3265 HRAS; Harvey rat sarcoma viral oncogene homolog hsa:3479 IGF1; insulin like growth factor 1 hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa04724 Glutamatergic synapse - Homo sapiens (human) (5)

hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:9456 HOMER1; homer scaffolding protein 1 hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:81539 SLC38A1; solute carrier family 38 member 1

hsa04918 Thyroid hormone synthesis - Homo sapiens (human) (5)

hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2878 GPX3; glutathione peroxidase 3 (EC:1.11.1.9) hsa:7184 HSP90B1; heat shock protein 90kDa beta family member 1 hsa:3309 HSPA5; heat shock protein family A (Hsp70) member 5

hsa00600 Sphingolipid metabolism - Homo sapiens (human) (5)

hsa:204219 CERS3; ceramide synthase 3 (EC:2.3.1.24) hsa:81537 SGPP1; sphingosine-1-phosphate phosphatase 1 hsa:55627 SMPD4; sphingomyelin phosphodiesterase 4 (EC:3.1.4.12) hsa:8877 SPHK1; sphingosine kinase 1 (EC:2.7.1.91) hsa:9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2 (EC:2.3.1.50)

hsa04972 Pancreatic secretion - Homo sapiens (human) (4)

hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:1361 CPB2; carboxypeptidase B2 (EC:3.4.17.20) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4) hsa:387 RHOA; ras homolog family member A

hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human) (4)

hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:1432 MAPK14; mitogen-activated protein kinase 14 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)

hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human) (4)

hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1) hsa:6514 SLC2A2; solute carrier family 2 member 2

hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human) (4)

hsa:2058 EPRS; glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) hsa:283459 GATC; glutamyl-tRNA(Gln) amidotransferase, subunit C hsa:118672 PSTK; phosphoseryl-tRNA kinase (EC:2.7.1.164) hsa:7453 WARS; tryptophanyl-tRNA synthetase (EC:6.1.1.2)

hsa00230 Purine metabolism - Homo sapiens (human) (4)

hsa:205 AK4; adenylate kinase 4 (EC:2.7.4.10 2.7.4.6) hsa:271 AMPD2; adenosine monophosphate deaminase 2 (EC:3.5.4.6) hsa:11164 NUDT5; nudix hydrolase 5 (EC:3.6.1.13 3.6.1.58) hsa:10846 PDE10A; phosphodiesterase 10A (EC:3.1.4.35 3.1.4.17)

hsa00190 Oxidative phosphorylation - Homo sapiens (human) (4)

hsa:496 ATP4B; ATPase H+/K+ transporting beta subunit hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa04971 Gastric acid secretion - Homo sapiens (human) (4)

hsa:60 ACTB; actin, beta hsa:496 ATP4B; ATPase H+/K+ transporting beta subunit hsa:2520 GAST; gastrin hsa:3766 KCNJ10; potassium voltage-gated channel subfamily J member 10

hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human) (4)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16) hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:1629 DBT; dihydrolipoamide branched chain transacylase E2 (EC:2.3.1.168) hsa:5019 OXCT1; 3-oxoacid CoA-transferase 1 (EC:2.8.3.5)

hsa04727 GABAergic synapse - Homo sapiens (human) (4)

hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:5334 PLCL1; phospholipase C like 1 hsa:81539 SLC38A1; solute carrier family 38 member 1 hsa:6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase (EC:2.7.10.2)

hsa00480 Glutathione metabolism - Homo sapiens (human) (4)

hsa:2878 GPX3; glutathione peroxidase 3 (EC:1.11.1.9) hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1) hsa:4953 ODC1; ornithine decarboxylase 1 (EC:4.1.1.17)

hsa03015 mRNA surveillance pathway - Homo sapiens (human) (4)

hsa:81608 FIP1L1; factor interacting with PAPOLA and CPSF1 hsa:4686 NCBP1; nuclear cap binding protein subunit 1 hsa:8761 PABPC4; poly(A) binding protein cytoplasmic 4 hsa:51585 PCF11; PCF11 cleavage and polyadenylation factor subunit

hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human) (4)

hsa:468 ATF4; activating transcription factor 4 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:3164 NR4A1; nuclear receptor subfamily 4 group A member 1 hsa:4929 NR4A2; nuclear receptor subfamily 4 group A member 2

hsa00410 beta-Alanine metabolism - Homo sapiens (human) (4)

hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:84735 CNDP1; carnosine dipeptidase 1 (metallopeptidase M20 family) (EC:3.4.13.20) hsa:1807 DPYS; dihydropyrimidinase (EC:3.5.2.2) hsa:54498 SMOX; spermine oxidase (EC:1.5.3.16)

hsa04713 Circadian entrainment - Homo sapiens (human) (4)

hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:2353 FOS; Fos proto-oncogene, AP-1 trancription factor subunit hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa04976 Bile secretion - Homo sapiens (human) (4)

hsa:8714 ABCC3; ATP binding cassette subfamily C member 3 hsa:3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) hsa:6513 SLC2A1; solute carrier family 2 member 1 hsa:6579 SLCO1A2; solute carrier organic anion transporter family member 1A2

hsa00450 Selenocompound metabolism - Homo sapiens (human) (4)

hsa:1491 CTH; cystathionine gamma-lyase (EC:4.4.1.1) hsa:118672 PSTK; phosphoseryl-tRNA kinase (EC:2.7.1.164) hsa:22928 SEPHS2; selenophosphate synthetase 2 (EC:2.7.9.3) hsa:7296 TXNRD1; thioredoxin reductase 1 (EC:1.8.1.9)

hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) (4)

hsa:624 BDKRB2; bradykinin receptor B2 hsa:1211 CLTA; clathrin light chain A hsa:1213 CLTC; clathrin heavy chain hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)

hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human) (4)

hsa:154 ADRB2; adrenoceptor beta 2 hsa:207 AKT1; AKT serine/threonine kinase 1 (EC:2.7.11.1) hsa:2167 FABP4; fatty acid binding protein 4 hsa:4852 NPY; neuropeptide Y

hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human) (4)

hsa:3479 IGF1; insulin like growth factor 1 hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24) hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24) hsa:6446 SGK1; serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1)

hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human) (4)

hsa:10528 NOP56; NOP56 ribonucleoprotein hsa:4931 NVL; nuclear VCP-like hsa:6949 TCOF1; treacle ribosome biogenesis factor 1 hsa:54464 XRN1; 5'-3' exoribonuclease 1

hsa00564 Glycerophospholipid metabolism - Homo sapiens (human) (4)

hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107) hsa:3931 LCAT; lecithin-cholesterol acyltransferase (EC:2.3.1.43) hsa:79888 LPCAT1; lysophosphatidylcholine acyltransferase 1 (EC:2.3.1.23 2.3.1.67) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4)

hsa01212 Fatty acid metabolism - Homo sapiens (human) (4)

hsa04710 Circadian rhythm - Homo sapiens (human) (4)

hsa:8553 BHLHE40; basic helix-loop-helix family member e40 hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:1407 CRY1; cryptochrome circadian clock 1 hsa:6097 RORC; RAR related orphan receptor C

hsa04330 Notch signaling pathway - Homo sapiens (human) (4)

hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86) hsa:3280 HES1; hes family bHLH transcription factor 1 hsa:3955 LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222) hsa:4851 NOTCH1; notch 1

hsa00052 Galactose metabolism - Homo sapiens (human) (4)

hsa04260 Cardiac muscle contraction - Homo sapiens (human) (4)

hsa:70 ACTC1; actin, alpha, cardiac muscle 1 hsa:7170 TPM3; tropomyosin 3 hsa:7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2) hsa:27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII (EC:1.10.2.2)

hsa04977 Vitamin digestion and absorption - Homo sapiens (human) (4)

hsa:335 APOA1; apolipoprotein A1 hsa:337 APOA4; apolipoprotein A4 hsa:338 APOB; apolipoprotein B hsa:686 BTD; biotinidase (EC:3.5.1.12)

hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human) (4)

hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107) hsa:3635 INPP5D; inositol polyphosphate-5-phosphatase D (EC:3.1.3.86) hsa:3636 INPPL1; inositol polyphosphate phosphatase like 1 (EC:3.1.3.86) hsa:9108 MTMR7; myotubularin related protein 7 (EC:3.1.3.-)

hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis - Homo sapiens (human) (3)

hsa:2822 GPLD1; glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50) hsa:80055 PGAP1; post-GPI attachment to proteins 1 hsa:5277 PIGA; phosphatidylinositol glycan anchor biosynthesis class A (EC:2.4.1.198)

hsa04950 Maturity onset diabetes of the young - Homo sapiens (human) (3)

hsa:3280 HES1; hes family bHLH transcription factor 1 hsa:2494 NR5A2; nuclear receptor subfamily 5 group A member 2 hsa:6514 SLC2A2; solute carrier family 2 member 2

hsa04924 Renin secretion - Homo sapiens (human) (3)

hsa:154 ADRB2; adrenoceptor beta 2 hsa:183 AGT; angiotensinogen hsa:1385 CREB1; cAMP responsive element binding protein 1

hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human) (3)

hsa:2673 GFPT1; glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16) hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1)

hsa04146 Peroxisome - Homo sapiens (human) (3)

hsa:225 ABCD2; ATP binding cassette subfamily D member 2 hsa:3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic (EC:1.1.1.42) hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39)

hsa00983 Drug metabolism - other enzymes - Homo sapiens (human) (3)

hsa:1807 DPYS; dihydropyrimidinase (EC:3.5.2.2) hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31) hsa:7371 UCK2; uridine-cytidine kinase 2 (EC:2.7.1.48)

hsa04913 Ovarian steroidogenesis - Homo sapiens (human) (3)

hsa:240 ALOX5; arachidonate 5-lipoxygenase (EC:1.13.11.34) hsa:654 BMP6; bone morphogenetic protein 6 hsa:3479 IGF1; insulin like growth factor 1

hsa05110 Vibrio cholerae infection - Homo sapiens (human) (3)

hsa:60 ACTB; actin, beta hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:11015 KDELR3; KDEL endoplasmic reticulum protein retention receptor 3

hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human) (3)

hsa:440 ASNS; asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) hsa:2673 GFPT1; glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16) hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2)

hsa00640 Propanoate metabolism - Homo sapiens (human) (3)

hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) hsa:1629 DBT; dihydrolipoamide branched chain transacylase E2 (EC:2.3.1.168) hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)

hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human) (3)

hsa:397 ARHGDIB; Rho GDP dissociation inhibitor beta hsa:1385 CREB1; cAMP responsive element binding protein 1 hsa:6810 STX4; syntaxin 4

hsa00071 Fatty acid degradation - Homo sapiens (human) (3)

hsa04966 Collecting duct acid secretion - Homo sapiens (human) (3)

hsa:496 ATP4B; ATPase H+/K+ transporting beta subunit hsa:23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2 (EC:3.6.3.6) hsa:6521 SLC4A1; solute carrier family 4 member 1 (Diego blood group)

hsa04140 Regulation of autophagy - Homo sapiens (human) (3)

hsa:9474 ATG5; autophagy related 5 hsa:10533 ATG7; autophagy related 7 hsa:3458 IFNG; interferon, gamma

hsa00240 Pyrimidine metabolism - Homo sapiens (human) (3)

hsa:1807 DPYS; dihydropyrimidinase (EC:3.5.2.2) hsa:7296 TXNRD1; thioredoxin reductase 1 (EC:1.8.1.9) hsa:7371 UCK2; uridine-cytidine kinase 2 (EC:2.7.1.48)

hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series - Homo sapiens (human) (2)

hsa:2529 FUT7; fucosyltransferase 7 (EC:2.4.1.-) hsa:2651 GCNT2; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (EC:2.4.1.150)

hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human) (2)

hsa:1491 CTH; cystathionine gamma-lyase (EC:4.4.1.1) hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)

hsa00670 One carbon pool by folate - Homo sapiens (human) (2)

hsa:25902 MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3) hsa:10797 MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15)

hsa00591 Linoleic acid metabolism - Homo sapiens (human) (2)

hsa:246 ALOX15; arachidonate 15-lipoxygenase (EC:1.13.11.31 1.13.11.33) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4)

hsa00220 Arginine biosynthesis - Homo sapiens (human) (2)

hsa:27165 GLS2; glutaminase 2 (EC:3.5.1.2) hsa:4843 NOS2; nitric oxide synthase 2 (EC:1.14.13.39)

hsa03430 Mismatch repair - Homo sapiens (human) (2)

hsa:27030 MLH3; mutL homolog 3 hsa:5981 RFC1; replication factor C subunit 1

hsa00561 Glycerolipid metabolism - Homo sapiens (human) (2)

hsa:57016 AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) hsa:1608 DGKG; diacylglycerol kinase gamma (EC:2.7.1.107)

hsa00340 Histidine metabolism - Homo sapiens (human) (2)

hsa:84735 CNDP1; carnosine dipeptidase 1 (metallopeptidase M20 family) (EC:3.4.13.20) hsa:3067 HDC; histidine decarboxylase (EC:4.1.1.22)

hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human) (2)

hsa:952 CD38; CD38 molecule (EC:3.2.2.6 2.4.99.20) hsa:10135 NAMPT; nicotinamide phosphoribosyltransferase (EC:2.4.2.12)

hsa03060 Protein export - Homo sapiens (human) (2)

hsa:3309 HSPA5; heat shock protein family A (Hsp70) member 5 hsa:5018 OXA1L; OXA1L, mitochondrial inner membrane protein

hsa00270 Cysteine and methionine metabolism - Homo sapiens (human) (2)

hsa:1491 CTH; cystathionine gamma-lyase (EC:4.4.1.1) hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)

hsa00604 Glycosphingolipid biosynthesis - ganglio series - Homo sapiens (human) (2)

hsa:6482 ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (EC:2.4.99.4) hsa:27090 ST6GALNAC4; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (EC:2.4.99.7)

hsa00524 Neomycin, kanamycin and gentamicin biosynthesis - Homo sapiens (human) (2)

hsa:3098 HK1; hexokinase 1 (EC:2.7.1.1) hsa:3099 HK2; hexokinase 2 (EC:2.7.1.1)

hsa00030 Pentose phosphate pathway - Homo sapiens (human) (2)

hsa:5214 PFKP; phosphofructokinase, platelet (EC:2.7.1.11) hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2)

hsa00512 Mucin type O-Glycan biosynthesis - Homo sapiens (human) (2)

hsa:51809 GALNT7; polypeptide N-acetylgalactosaminyltransferase 7 (EC:2.4.1.41) hsa:6482 ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (EC:2.4.99.4)

hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human) (2)

hsa:2529 FUT7; fucosyltransferase 7 (EC:2.4.1.-) hsa:3955 LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222)

hsa00510 N-Glycan biosynthesis - Homo sapiens (human) (2)

hsa:4122 MAN2A2; mannosidase alpha class 2A member 2 (EC:3.2.1.114) hsa:201595 STT3B; STT3B, catalytic subunit of the oligosaccharyltransferase complex (EC:2.4.99.18)

hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human) (2)

hsa:57016 AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) hsa:2990 GUSB; glucuronidase beta (EC:3.2.1.31)

hsa04614 Renin-angiotensin system - Homo sapiens (human) (2)

hsa:183 AGT; angiotensinogen hsa:1511 CTSG; cathepsin G (EC:3.4.21.20)

hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate - Homo sapiens (human) (2)

hsa:50515 CHST11; carbohydrate (chondroitin 4) sulfotransferase 11 (EC:2.8.2.5) hsa:113189 CHST14; carbohydrate sulfotransferase 14 (EC:2.8.2.35)

hsa00062 Fatty acid elongation - Homo sapiens (human) (2)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16) hsa:51144 HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12 (EC:1.1.1.62 1.1.1.330)

hsa00565 Ether lipid metabolism - Homo sapiens (human) (2)

hsa:79888 LPCAT1; lysophosphatidylcholine acyltransferase 1 (EC:2.3.1.23 2.3.1.67) hsa:5322 PLA2G5; phospholipase A2 group V (EC:3.1.1.4)

hsa03460 Fanconi anemia pathway - Homo sapiens (human) (1)

hsa:3280 HES1; hes family bHLH transcription factor 1