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hsa01100 Metabolic pathways - Homo sapiens (human) (128)

cpd:C00003 NAD+
cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00033 Acetate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00042 Succinate
cpd:C00049 L-Aspartate
cpd:C00058 Formate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00114 Choline
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00137 myo-Inositol
cpd:C00183 L-Valine
cpd:C00186 (S)-Lactate
cpd:C00187 Cholesterol
cpd:C00188 L-Threonine
cpd:C00267 alpha-D-Glucose
cpd:C00300 Creatine
cpd:C00346 Ethanolamine phosphate
cpd:C00407 L-Isoleucine
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
cpd:C01042 N-Acetyl-L-aspartate
cpd:C01595 Linoleate
hsa:10157 AASS; aminoadipate-semialdehyde synthase (EC:1.5.1.8 1.5.1.9)
hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16)
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:37 ACADVL; acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:55902 ACSS2; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1)
hsa:191 AHCY; adenosylhomocysteinase (EC:3.3.1.1)
hsa:6718 AKR1D1; aldo-keto reductase family 1, member D1 (EC:1.3.1.3)
hsa:5832 ALDH18A1; aldehyde dehydrogenase 18 family, member A1 (EC:1.2.1.41 2.7.2.11)
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:440 ASNS; asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)
hsa:498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
hsa:509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (EC:3.6.1.14)
hsa:515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
hsa:10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d (EC:3.6.1.14)
hsa:521 ATP5I; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (EC:3.6.1.14)
hsa:9551 ATP5J2; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 (EC:3.6.1.14)
hsa:539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)
hsa:4509 ATP8; ATP synthase F0 subunit 8
hsa:549 AUH; AU RNA binding protein/enoyl-CoA hydratase (EC:4.2.1.18)
hsa:790 CAD; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5)
hsa:1158 CKM; creatine kinase, muscle (EC:2.7.3.2)
hsa:10063 COX17; COX17 cytochrome c oxidase copper chaperone
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:1737 DLAT; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:1743 DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:2194 FASN; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)
hsa:2224 FDPS; farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:2356 FPGS; folylpolyglutamate synthase (EC:6.3.2.17)
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (EC:2.1.2.2 6.3.3.1 6.3.4.13)
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4)
hsa:3155 HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4)
hsa:3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)
hsa:3295 HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12)
hsa:3419 IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)
hsa:3615 IMPDH2; IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205)
hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)
hsa:4048 LTA4H; leukotriene A4 hydrolase (EC:3.3.2.6)
hsa:4144 MAT2A; methionine adenosyltransferase II, alpha (EC:2.5.1.6)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
hsa:51102 MECR; mitochondrial trans-2-enoyl-CoA reductase (EC:1.3.1.38)
hsa:25902 MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3)
hsa:10797 MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15)
hsa:54187 NANS; N-acetylneuraminic acid synthase (EC:2.5.1.56 2.5.1.57)
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:4942 OAT; ornithine aminotransferase (EC:2.6.1.13)
hsa:5048 PAFAH1B1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) (EC:3.1.1.47)
hsa:5050 PAFAH1B3; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) (EC:3.1.1.47)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:8050 PDHX; pyruvate dehydrogenase complex, component X
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:5226 PGD; phosphogluconate dehydrogenase (EC:1.1.1.44)
hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3)
hsa:5232 PGK2; phosphoglycerate kinase 2 (EC:2.7.2.3)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:26227 PHGDH; phosphoglycerate dehydrogenase (EC:1.1.1.95)
hsa:5409 PNMT; phenylethanolamine N-methyltransferase (EC:2.1.1.28)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)
hsa:9588 PRDX6; peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)
hsa:221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)
hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)
hsa:9791 PTDSS1; phosphatidylserine synthase 1 (EC:2.7.8.29)
hsa:10728 PTGES3; prostaglandin E synthase 3 (cytosolic) (EC:5.3.99.3)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:5836 PYGL; phosphorylase, glycogen, liver (EC:2.4.1.1)
hsa:5980 REV3L; REV3-like, polymerase (DNA directed), zeta, catalytic subunit (EC:2.7.7.7)
hsa:6185 RPN2; ribophorin II (EC:2.4.99.18)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:22929 SEPHS1; selenophosphate synthetase 1 (EC:2.7.9.3)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)
hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2)
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)
hsa:7086 TKT; transketolase (EC:2.2.1.1)
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)
hsa:6675 UAP1; UDP-N-acetylglucosamine pyrophosphorylase 1 (EC:2.7.7.23 2.7.7.83)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa05200 Pathways in cancer - Homo sapiens (human) (51)

cpd:C00187 Cholesterol
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1487 CTBP1; C-terminal binding protein 1
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:54205 CYCS; cytochrome c, somatic
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:1910 EDNRB; endothelin receptor type B
hsa:1950 EGF; epidermal growth factor
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:355 FAS; Fas cell surface death receptor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6469 SHH; sonic hedgehog
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:6923 TCEB2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7157 TP53; tumor protein p53
hsa:7170 TPM3; tropomyosin 3
hsa:7175 TPR; translocated promoter region, nuclear basket protein
hsa:7422 VEGFA; vascular endothelial growth factor A
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa01200 Carbon metabolism - Homo sapiens (human) (45)

cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00033 Acetate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00042 Succinate
cpd:C00049 L-Aspartate
cpd:C00058 Formate
cpd:C00267 alpha-D-Glucose
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:55902 ACSS2; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1)
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:1737 DLAT; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:1743 DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4)
hsa:3419 IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:5226 PGD; phosphogluconate dehydrogenase (EC:1.1.1.44)
hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3)
hsa:5232 PGK2; phosphoglycerate kinase 2 (EC:2.7.2.3)
hsa:26227 PHGDH; phosphoglycerate dehydrogenase (EC:1.1.1.95)
hsa:221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)
hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)
hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2)
hsa:7086 TKT; transketolase (EC:2.2.1.1)
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa04010 MAPK signaling pathway - Homo sapiens (human) (43)

hsa:468 ATF4; activating transcription factor 4
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1649 DDIT3; DNA-damage-inducible transcript 3
hsa:1950 EGF; epidermal growth factor
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:355 FAS; Fas cell surface death receptor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:2316 FLNA; filamin A, alpha
hsa:2317 FLNB; filamin B, beta
hsa:2318 FLNC; filamin C, gamma
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:1647 GADD45A; growth arrest and DNA-damage-inducible, alpha
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11 (EC:2.7.11.25)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4208 MEF2C; myocyte enhancer factor 2C
hsa:4763 NF1; neurofibromin 1
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4908 NTF3; neurotrophin 3
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:4915 NTRK2; neurotrophic tyrosine kinase, receptor, type 2 (EC:2.7.10.1)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
hsa:3925 STMN1; stathmin 1
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53

hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human) (43)

hsa:650 BMP2; bone morphogenetic protein 2
hsa:655 BMP7; bone morphogenetic protein 7
hsa:6346 CCL1; chemokine (C-C motif) ligand 1
hsa:6356 CCL11; chemokine (C-C motif) ligand 11
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:1234 CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene)
hsa:6376 CX3CL1; chemokine (C-X3-C motif) ligand 1
hsa:1524 CX3CR1; chemokine (C-X3-C motif) receptor 1
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:2833 CXCR3; chemokine (C-X-C motif) receptor 3
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:1950 EGF; epidermal growth factor
hsa:355 FAS; Fas cell surface death receptor
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3596 IL13; interleukin 13
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:3624 INHBA; inhibin, beta A
hsa:3626 INHBC; inhibin, beta C
hsa:83729 INHBE; inhibin, beta E
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:4804 NGFR; nerve growth factor receptor
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7133 TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B
hsa:7422 VEGFA; vascular endothelial growth factor A
hsa:6375 XCL1; chemokine (C motif) ligand 1

hsa05164 Influenza A - Homo sapiens (human) (42)

hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:54205 CYCS; cytochrome c, somatic
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:355 FAS; Fas cell surface death receptor
hsa:2224 FDPS; farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)
hsa:5045 FURIN; furin (paired basic amino acid cleaving enzyme) (EC:3.4.21.75)
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7514 XPO1; exportin 1

hsa05168 Herpes simplex infection - Homo sapiens (human) (39)

hsa:727 C5; complement component 5
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:1936 EEF1D; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:355 FAS; Fas cell surface death receptor
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3725 JUN; jun proto-oncogene
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:10929 SRSF8; serine/arginine-rich splicing factor 8
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:6908 TBP; TATA box binding protein
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53

hsa05206 MicroRNAs in cancer - Homo sapiens (human) (39)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:900 CCNG1; cyclin G1
hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:7430 EZR; ezrin
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:9759 HDAC4; histone deacetylase 4 (EC:3.5.1.98)
hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3)
hsa:3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:4082 MARCKS; myristoylated alanine-rich protein kinase C substrate
hsa:406906 MIR122; microRNA 122
hsa:406913 MIR126; microRNA 126
hsa:406937 MIR145; microRNA 145
hsa:406938 MIR146A; microRNA 146a
hsa:406947 MIR155; microRNA 155
hsa:406967 MIR192; microRNA 192
hsa:406984 MIR200B; microRNA 200b
hsa:407008 MIR223; microRNA 223
hsa:554213 MIR449A; microRNA 449a
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4851 NOTCH1; notch 1
hsa:4853 NOTCH2; notch 2
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:3925 STMN1; stathmin 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7143 TNR; tenascin R
hsa:7157 TP53; tumor protein p53
hsa:7422 VEGFA; vascular endothelial growth factor A
hsa:7431 VIM; vimentin

hsa05166 HTLV-I infection - Homo sapiens (human) (39)

hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:598 BCL2L1; BCL2-like 1
hsa:811 CALR; calreticulin
hsa:821 CANX; calnexin
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:1958 EGR1; early growth response 1
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2224 FDPS; farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3558 IL2; interleukin 2
hsa:3725 JUN; jun proto-oncogene
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:8829 NRP1; neuropilin 1
hsa:5901 RAN; RAN, member RAS oncogene family
hsa:5902 RANBP1; RAN binding protein 1
hsa:292 SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:6908 TBP; TATA box binding protein
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7094 TLN1; talin 1
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53
hsa:7412 VCAM1; vascular cell adhesion molecule 1
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7417 VDAC2; voltage-dependent anion channel 2
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A
hsa:7494 XBP1; X-box binding protein 1
hsa:7514 XPO1; exportin 1

hsa05169 Epstein-Barr virus infection - Homo sapiens (human) (36)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:9759 HDAC4; histone deacetylase 4 (EC:3.5.1.98)
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3586 IL10; interleukin 10
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3725 JUN; jun proto-oncogene
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5706 PSMC6; proteasome (prosome, macropain) 26S subunit, ATPase, 6
hsa:5707 PSMD1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
hsa:5718 PSMD12; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
hsa:5710 PSMD4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
hsa:5713 PSMD7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
hsa:5901 RAN; RAN, member RAS oncogene family
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:6908 TBP; TATA box binding protein
hsa:7157 TP53; tumor protein p53
hsa:7431 VIM; vimentin
hsa:7514 XPO1; exportin 1
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa05203 Viral carcinogenesis - Homo sapiens (human) (36)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1234 CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene)
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:9759 HDAC4; histone deacetylase 4 (EC:3.5.1.98)
hsa:255626 HIST1H2BA; histone cluster 1, H2ba
hsa:3018 HIST1H2BB; histone cluster 1, H2bb
hsa:3017 HIST1H2BD; histone cluster 1, H2bd
hsa:8343 HIST1H2BF; histone cluster 1, H2bf
hsa:8345 HIST1H2BH; histone cluster 1, H2bh
hsa:85236 HIST1H2BK; histone cluster 1, H2bk
hsa:8342 HIST1H2BM; histone cluster 1, H2bm
hsa:8365 HIST1H4H; histone cluster 1, H4h
hsa:440689 HIST2H2BF; histone cluster 2, H2bf
hsa:3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:5902 RANBP1; RAN binding protein 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:6908 TBP; TATA box binding protein
hsa:7157 TP53; tumor protein p53
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human) (35)


cpd:C00533 Nitric oxide
hsa:468 ATF4; activating transcription factor 4
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:11140 CDC37; cell division cycle 37
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1950 EGF; epidermal growth factor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3558 IL2; interleukin 2
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4804 NGFR; nerve growth factor receptor
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7143 TNR; tenascin R
hsa:7157 TP53; tumor protein p53
hsa:7422 VEGFA; vascular endothelial growth factor A
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa05010 Alzheimer's disease - Homo sapiens (human) (35)

cpd:C00533 Nitric oxide
cpd:C16845 Peroxynitrite
hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86)
hsa:322 APBB1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
hsa:348 APOE; apolipoprotein E
hsa:22926 ATF6; activating transcription factor 6
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:489 ATP2A3; ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)
hsa:498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
hsa:509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (EC:3.6.1.14)
hsa:515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
hsa:10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d (EC:3.6.1.14)
hsa:539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)
hsa:4509 ATP8; ATP synthase F0 subunit 8
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:8851 CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35)
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:2081 ERN1; endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1)
hsa:355 FAS; Fas cell surface death receptor
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3553 IL1B; interleukin 1, beta
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:6263 RYR3; ryanodine receptor 3
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa05161 Hepatitis B - Homo sapiens (human) (34)

hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:54205 CYCS; cytochrome c, somatic
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:355 FAS; Fas cell surface death receptor
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7157 TP53; tumor protein p53
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa05016 Huntington's disease - Homo sapiens (human) (34)

cpd:C00025 L-Glutamate
hsa:498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
hsa:509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (EC:3.6.1.14)
hsa:515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
hsa:10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d (EC:3.6.1.14)
hsa:539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)
hsa:4509 ATP8; ATP synthase F0 subunit 8
hsa:581 BAX; BCL2-associated X protein
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:54205 CYCS; cytochrome c, somatic
hsa:10540 DCTN2; dynactin 2 (p50)
hsa:1742 DLG4; discs, large homolog 4 (Drosophila)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2876 GPX1; glutathione peroxidase 1 (EC:1.11.1.9)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:10105 PPIF; peptidylprolyl isomerase F (EC:5.2.1.8)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:292 SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:6647 SOD1; superoxide dismutase 1, soluble (EC:1.15.1.1)
hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1)
hsa:6908 TBP; TATA box binding protein
hsa:7157 TP53; tumor protein p53
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7417 VDAC2; voltage-dependent anion channel 2

hsa01230 Biosynthesis of amino acids - Homo sapiens (human) (34)

cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:5832 ALDH18A1; aldehyde dehydrogenase 18 family, member A1 (EC:1.2.1.41 2.7.2.11)
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:3419 IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)
hsa:4144 MAT2A; methionine adenosyltransferase II, alpha (EC:2.5.1.6)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3)
hsa:5232 PGK2; phosphoglycerate kinase 2 (EC:2.7.2.3)
hsa:26227 PHGDH; phosphoglycerate dehydrogenase (EC:1.1.1.95)
hsa:221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)
hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)
hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2)
hsa:7086 TKT; transketolase (EC:2.2.1.1)
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa05034 Alcoholism - Homo sapiens (human) (30)

cpd:C00025 L-Glutamate
cpd:C00082 L-Tyrosine
hsa:135 ADORA2A; adenosine A2a receptor
hsa:468 ATF4; activating transcription factor 4
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1813 DRD2; dopamine receptor D2
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:55766 H2AFJ; H2A histone family, member J
hsa:94239 H2AFV; H2A histone family, member V
hsa:3014 H2AFX; H2A histone family, member X
hsa:9759 HDAC4; histone deacetylase 4 (EC:3.5.1.98)
hsa:8330 HIST1H2AK; histone cluster 1, H2ak
hsa:255626 HIST1H2BA; histone cluster 1, H2ba
hsa:3018 HIST1H2BB; histone cluster 1, H2bb
hsa:3017 HIST1H2BD; histone cluster 1, H2bd
hsa:8343 HIST1H2BF; histone cluster 1, H2bf
hsa:8345 HIST1H2BH; histone cluster 1, H2bh
hsa:85236 HIST1H2BK; histone cluster 1, H2bk
hsa:8342 HIST1H2BM; histone cluster 1, H2bm
hsa:8968 HIST1H3F; histone cluster 1, H3f
hsa:8365 HIST1H4H; histone cluster 1, H4h
hsa:440689 HIST2H2BF; histone cluster 2, H2bf
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4852 NPY; neuropeptide Y
hsa:4915 NTRK2; neurotrophic tyrosine kinase, receptor, type 2 (EC:2.7.10.1)
hsa:5173 PDYN; prodynorphin
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa04024 cAMP signaling pathway - Homo sapiens (human) (30)

cpd:C00042 Succinate
cpd:C00186 (S)-Lactate
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
hsa:134 ADORA1; adenosine A1 receptor
hsa:135 ADORA2A; adenosine A2a receptor
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1813 DRD2; dopamine receptor D2
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:5348 FXYD1; FXYD domain containing ion transport regulator 1
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3350 HTR1A; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
hsa:3351 HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
hsa:3355 HTR1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4852 NPY; neuropeptide Y
hsa:5139 PDE3A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human) (30)

cpd:C00533 Nitric oxide
hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:811 CALR; calreticulin
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:355 FAS; Fas cell surface death receptor
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa05162 Measles - Homo sapiens (human) (29)

hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:8667 EIF3H; eukaryotic translation initiation factor 3, subunit H
hsa:355 FAS; Fas cell surface death receptor
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3596 IL13; interleukin 13
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7157 TP53; tumor protein p53

hsa03010 Ribosome - Homo sapiens (human) (28)

hsa:4736 RPL10A; ribosomal protein L10a (EC:3.6.5.3)
hsa:6135 RPL11; ribosomal protein L11
hsa:6137 RPL13; ribosomal protein L13 (EC:3.6.5.3)
hsa:23521 RPL13A; ribosomal protein L13a
hsa:9045 RPL14; ribosomal protein L14
hsa:6138 RPL15; ribosomal protein L15
hsa:6142 RPL18A; ribosomal protein L18a
hsa:6143 RPL19; ribosomal protein L19
hsa:6144 RPL21; ribosomal protein L21 (EC:3.6.5.3)
hsa:9349 RPL23; ribosomal protein L23
hsa:6147 RPL23A; ribosomal protein L23a
hsa:6122 RPL3; ribosomal protein L3
hsa:6156 RPL30; ribosomal protein L30
hsa:6164 RPL34; ribosomal protein L34
hsa:6165 RPL35A; ribosomal protein L35a
hsa:6167 RPL37; ribosomal protein L37
hsa:6124 RPL4; ribosomal protein L4
hsa:6125 RPL5; ribosomal protein L5
hsa:6128 RPL6; ribosomal protein L6
hsa:6130 RPL7A; ribosomal protein L7a
hsa:6207 RPS13; ribosomal protein S13 (EC:3.6.5.3)
hsa:6229 RPS24; ribosomal protein S24
hsa:6233 RPS27A; ribosomal protein S27a
hsa:6189 RPS3A; ribosomal protein S3A
hsa:6191 RPS4X; ribosomal protein S4, X-linked
hsa:6201 RPS7; ribosomal protein S7 (EC:3.6.5.3)
hsa:6203 RPS9; ribosomal protein S9
hsa:7311 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1

hsa05205 Proteoglycans in cancer - Homo sapiens (human) (28)

hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:859 CAV3; caveolin 3
hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:2017 CTTN; cortactin
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:7430 EZR; ezrin
hsa:355 FAS; Fas cell surface death receptor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:2316 FLNA; filamin A, alpha
hsa:2317 FLNB; filamin B, beta
hsa:2318 FLNC; filamin C, gamma
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3593 IL12B; interleukin 12B
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7157 TP53; tumor protein p53
hsa:7422 VEGFA; vascular endothelial growth factor A
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human) (28)

hsa:468 ATF4; activating transcription factor 4
hsa:22926 ATF6; activating transcription factor 6
hsa:9532 BAG2; BCL2-associated athanogene 2
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:811 CALR; calreticulin
hsa:821 CANX; calnexin
hsa:1649 DDIT3; DNA-damage-inducible transcript 3
hsa:10294 DNAJA2; DnaJ (Hsp40) homolog, subfamily A, member 2
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:2081 ERN1; endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1)
hsa:9709 HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5034 P4HB; prolyl 4-hydroxylase, beta polypeptide (EC:5.3.4.1)
hsa:2923 PDIA3; protein disulfide isomerase family A, member 3 (EC:5.3.4.1)
hsa:6185 RPN2; ribophorin II (EC:2.4.99.18)
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:56886 UGGT1; UDP-glucose glycoprotein glucosyltransferase 1
hsa:7494 XBP1; X-box binding protein 1

hsa05152 Tuberculosis - Homo sapiens (human) (28)

hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:64170 CARD9; caspase recruitment domain family, member 9
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:54205 CYCS; cytochrome c, somatic
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:3313 HSPA9; heat shock 70kDa protein 9 (mortalin)
hsa:3440 IFNA2; interferon, alpha 2
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human) (27)

hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:1649 DDIT3; DNA-damage-inducible transcript 3
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:2081 ERN1; endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1)
hsa:355 FAS; Fas cell surface death receptor
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11 (EC:2.7.11.25)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7494 XBP1; X-box binding protein 1

hsa04066 HIF-1 signaling pathway - Homo sapiens (human) (27)

cpd:C00022 Pyruvate
cpd:C00186 (S)-Lactate
cpd:C00533 Nitric oxide
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1950 EGF; epidermal growth factor
hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3)
hsa:3458 IFNG; interferon, gamma
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3)
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:6923 TCEB2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05230 Central carbon metabolism in cancer - Homo sapiens (human) (26)

cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00042 Succinate
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00183 L-Valine
cpd:C00186 (S)-Lactate
cpd:C00407 L-Isoleucine
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:4916 NTRK3; neurotrophic tyrosine kinase, receptor, type 3 (EC:2.7.10.1)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:7157 TP53; tumor protein p53

hsa04722 Neurotrophin signaling pathway - Homo sapiens (human) (25)

hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4804 NGFR; nerve growth factor receptor
hsa:4908 NTF3; neurotrophin 3
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:4915 NTRK2; neurotrophic tyrosine kinase, receptor, type 2 (EC:2.7.10.1)
hsa:4916 NTRK3; neurotrophic tyrosine kinase, receptor, type 3 (EC:2.7.10.1)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
hsa:6272 SORT1; sortilin 1
hsa:7157 TP53; tumor protein p53
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

hsa04144 Endocytosis - Homo sapiens (human) (25)

hsa:116984 ARAP2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:859 CAV3; caveolin 3
hsa:1234 CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene)
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:1759 DNM1; dynamin 1 (EC:3.6.5.5)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:1950 EGF; epidermal growth factor
hsa:2060 EPS15; epidermal growth factor receptor pathway substrate 15
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:3949 LDLR; low density lipoprotein receptor
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:8766 RAB11A; RAB11A, member RAS oncogene family
hsa:9230 RAB11B; RAB11B, member RAS oncogene family
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7456 WIPF1; WAS/WASL interacting protein family, member 1

hsa05145 Toxoplasmosis - Homo sapiens (human) (25)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1234 CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene)
hsa:54205 CYCS; cytochrome c, somatic
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3949 LDLR; low density lipoprotein receptor
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:10105 PPIF; peptidylprolyl isomerase F (EC:5.2.1.8)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human) (25)

hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7124 TNF; tumor necrosis factor

hsa04380 Osteoclast differentiation - Homo sapiens (human) (24)

hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2274 FHL2; four and a half LIM domains 2
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:3726 JUNB; jun B proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa04668 TNF signaling pathway - Homo sapiens (human) (24)

hsa:468 ATF4; activating transcription factor 4
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:6376 CX3CL1; chemokine (C-X3-C motif) ligand 1
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:355 FAS; Fas cell surface death receptor
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:3726 JUNB; jun B proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7133 TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human) (24)

hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:1958 EGR1; early growth response 1
hsa:2152 F3; coagulation factor III (thromboplastin, tissue factor)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor
hsa:7412 VCAM1; vascular cell adhesion molecule 1
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05012 Parkinson's disease - Homo sapiens (human) (24)

cpd:C00082 L-Tyrosine
hsa:135 ADORA2A; adenosine A2a receptor
hsa:498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
hsa:509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (EC:3.6.1.14)
hsa:515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
hsa:10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d (EC:3.6.1.14)
hsa:539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)
hsa:4509 ATP8; ATP synthase F0 subunit 8
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:1813 DRD2; dopamine receptor D2
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:10105 PPIF; peptidylprolyl isomerase F (EC:5.2.1.8)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)
hsa:292 SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)
hsa:7345 UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7417 VDAC2; voltage-dependent anion channel 2

hsa05322 Systemic lupus erythematosus - Homo sapiens (human) (23)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:727 C5; complement component 5
hsa:55766 H2AFJ; H2A histone family, member J
hsa:94239 H2AFV; H2A histone family, member V
hsa:3014 H2AFX; H2A histone family, member X
hsa:8330 HIST1H2AK; histone cluster 1, H2ak
hsa:255626 HIST1H2BA; histone cluster 1, H2ba
hsa:3018 HIST1H2BB; histone cluster 1, H2bb
hsa:3017 HIST1H2BD; histone cluster 1, H2bd
hsa:8343 HIST1H2BF; histone cluster 1, H2bf
hsa:8345 HIST1H2BH; histone cluster 1, H2bh
hsa:85236 HIST1H2BK; histone cluster 1, H2bk
hsa:8342 HIST1H2BM; histone cluster 1, H2bm
hsa:8968 HIST1H3F; histone cluster 1, H3f
hsa:8365 HIST1H4H; histone cluster 1, H4h
hsa:440689 HIST2H2BF; histone cluster 2, H2bf
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:6741 SSB; Sjogren syndrome antigen B (autoantigen La)
hsa:7124 TNF; tumor necrosis factor

hsa05132 Salmonella infection - Homo sapiens (human) (23)

cpd:C00533 Nitric oxide
hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:1778 DYNC1H1; dynein, cytoplasmic 1, heavy chain 1
hsa:2316 FLNA; filamin A, alpha
hsa:2317 FLNB; filamin B, beta
hsa:2318 FLNC; filamin C, gamma
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3458 IFNG; interferon, gamma
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4627 MYH9; myosin, heavy chain 9, non-muscle
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5216 PFN1; profilin 1
hsa:5217 PFN2; profilin 2
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04068 FoxO signaling pathway - Homo sapiens (human) (23)

cpd:C00025 L-Glutamate
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:891 CCNB1; cyclin B1
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1950 EGF; epidermal growth factor
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:11337 GABARAP; GABA(A) receptor-associated protein
hsa:1647 GADD45A; growth arrest and DNA-damage-inducible, alpha
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3586 IL10; interleukin 10
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)

hsa04510 Focal adhesion - Homo sapiens (human) (22)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:859 CAV3; caveolin 3
hsa:1950 EGF; epidermal growth factor
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:2316 FLNA; filamin A, alpha
hsa:2317 FLNB; filamin B, beta
hsa:2318 FLNC; filamin C, gamma
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:3725 JUN; jun proto-oncogene
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7094 TLN1; talin 1
hsa:7143 TNR; tenascin R
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05160 Hepatitis C - Homo sapiens (human) (22)

hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1950 EGF; epidermal growth factor
hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2)
hsa:9451 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:3949 LDLR; low density lipoprotein receptor
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53

hsa05140 Leishmaniasis - Homo sapiens (human) (22)

cpd:C00533 Nitric oxide
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3565 IL4; interleukin 4
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:65108 MARCKSL1; MARCKS-like 1
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor

hsa05133 Pertussis - Homo sapiens (human) (21)

hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:727 C5; complement component 5
hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:1072 CFL1; cofilin 1 (non-muscle)
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3725 JUN; jun proto-oncogene
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:7124 TNF; tumor necrosis factor

hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human) (21)

cpd:C00533 Nitric oxide
hsa:134 ADORA1; adenosine A1 receptor
hsa:468 ATF4; activating transcription factor 4
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:489 ATP2A3; ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1910 EDNRB; endothelin receptor type B
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4208 MEF2C; myocyte enhancer factor 2C
hsa:5139 PDE3A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17)
hsa:10105 PPIF; peptidylprolyl isomerase F (EC:5.2.1.8)
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:292 SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7417 VDAC2; voltage-dependent anion channel 2

hsa04014 Ras signaling pathway - Homo sapiens (human) (21)

hsa:598 BCL2L1; BCL2-like 1
hsa:1950 EGF; epidermal growth factor
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4763 NF1; neurofibromin 1
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4804 NGFR; nerve growth factor receptor
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04062 Chemokine signaling pathway - Homo sapiens (human) (20)

hsa:6346 CCL1; chemokine (C-C motif) ligand 1
hsa:6356 CCL11; chemokine (C-C motif) ligand 11
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:1234 CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene)
hsa:6376 CX3CL1; chemokine (C-X3-C motif) ligand 1
hsa:1524 CX3CR1; chemokine (C-X3-C motif) receptor 1
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:2833 CXCR3; chemokine (C-X-C motif) receptor 3
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:6375 XCL1; chemokine (C motif) ligand 1

hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human) (20)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine
hsa:55157 DARS2; aspartyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.12)
hsa:2617 GARS; glycyl-tRNA synthetase (EC:6.1.1.14)
hsa:55699 IARS2; isoleucyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.5)
hsa:23395 LARS2; leucyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.4)
hsa:79731 NARS2; asparaginyl-tRNA synthetase 2, mitochondrial (putative) (EC:6.1.1.22)
hsa:6897 TARS; threonyl-tRNA synthetase (EC:6.1.1.3)
hsa:8565 YARS; tyrosyl-tRNA synthetase (EC:6.1.1.1)
hsa:51067 YARS2; tyrosyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.1)

hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human) (20)

cpd:C00022 Pyruvate
cpd:C00033 Acetate
cpd:C00186 (S)-Lactate
cpd:C00267 alpha-D-Glucose
hsa:55902 ACSS2; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1)
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:1737 DLAT; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:5230 PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3)
hsa:5232 PGK2; phosphoglycerate kinase 2 (EC:2.7.2.3)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa05215 Prostate cancer - Homo sapiens (human) (20)

hsa:468 ATF4; activating transcription factor 4
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1950 EGF; epidermal growth factor
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:7157 TP53; tumor protein p53

hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human) (20)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00049 L-Aspartate
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
cpd:C11695 Anandamide
hsa:134 ADORA1; adenosine A1 receptor
hsa:135 ADORA2A; adenosine A2a receptor
hsa:1813 DRD2; dopamine receptor D2
hsa:1814 DRD3; dopamine receptor D3
hsa:1910 EDNRB; endothelin receptor type B
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:2898 GRIK2; glutamate receptor, ionotropic, kainate 2
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3350 HTR1A; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
hsa:3351 HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
hsa:3355 HTR1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
hsa:3356 HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human) (20)

cpd:C00025 L-Glutamate
cpd:C00533 Nitric oxide
cpd:C16845 Peroxynitrite
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:54205 CYCS; cytochrome c, somatic
hsa:2876 GPX1; glutathione peroxidase 1 (EC:1.11.1.9)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6647 SOD1; superoxide dismutase 1, soluble (EC:1.15.1.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7133 TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B
hsa:7157 TP53; tumor protein p53

hsa04350 TGF-beta signaling pathway - Homo sapiens (human) (20)

hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:655 BMP7; bone morphogenetic protein 7
hsa:656 BMP8B; bone morphogenetic protein 8b
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:3458 IFNG; interferon, gamma
hsa:3624 INHBA; inhibin, beta A
hsa:3626 INHBC; inhibin, beta C
hsa:83729 INHBE; inhibin, beta E
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:9241 NOG; noggin
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:4092 SMAD7; SMAD family member 7
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7124 TNF; tumor necrosis factor

hsa00190 Oxidative phosphorylation - Homo sapiens (human) (19)

cpd:C00003 NAD+
cpd:C00042 Succinate
hsa:498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
hsa:509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (EC:3.6.1.14)
hsa:515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
hsa:10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d (EC:3.6.1.14)
hsa:521 ATP5I; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (EC:3.6.1.14)
hsa:9551 ATP5J2; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 (EC:3.6.1.14)
hsa:539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)
hsa:4509 ATP8; ATP synthase F0 subunit 8
hsa:10063 COX17; COX17 cytochrome c oxidase copper chaperone
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:4697 NDUFA4; NDUFA4, mitochondrial complex associated (EC:1.6.5.3 1.6.99.3)
hsa:4702 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (EC:1.6.5.3 1.6.99.3)
hsa:374291 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
hsa:5464 PPA1; pyrophosphatase (inorganic) 1 (EC:3.6.1.1)
hsa:27068 PPA2; pyrophosphatase (inorganic) 2 (EC:3.6.1.1)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)

hsa04974 Protein digestion and absorption - Homo sapiens (human) (19)

cpd:C00014 Ammonia
cpd:C00025 L-Glutamate
cpd:C00033 Acetate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:1306 COL15A1; collagen, type XV, alpha 1
hsa:1357 CPA1; carboxypeptidase A1 (pancreatic) (EC:3.4.17.1)
hsa:6520 SLC3A2; solute carrier family 3 (amino acid transporter heavy chain), member 2

hsa04015 Rap1 signaling pathway - Homo sapiens (human) (18)

hsa:135 ADORA2A; adenosine A2a receptor
hsa:1813 DRD2; dopamine receptor D2
hsa:1950 EGF; epidermal growth factor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4804 NGFR; nerve growth factor receptor
hsa:5216 PFN1; profilin 1
hsa:5217 PFN2; profilin 2
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7094 TLN1; talin 1
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human) (18)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:1072 CFL1; cofilin 1 (non-muscle)
hsa:23191 CYFIP1; cytoplasmic FMR1 interacting protein 1
hsa:1950 EGF; epidermal growth factor
hsa:7430 EZR; ezrin
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4627 MYH9; myosin, heavy chain 9, non-muscle
hsa:5216 PFN1; profilin 1
hsa:5217 PFN2; profilin 2
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04630 Jak-STAT signaling pathway - Homo sapiens (human) (18)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2670 GFAP; glial fibrillary acidic protein
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3596 IL13; interleukin 13
hsa:3558 IL2; interleukin 2
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)

hsa05020 Prion diseases - Homo sapiens (human) (18)

hsa:581 BAX; BCL2-associated X protein
hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:727 C5; complement component 5
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:1958 EGR1; early growth response 1
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4851 NOTCH1; notch 1
hsa:6647 SOD1; superoxide dismutase 1, soluble (EC:1.15.1.1)
hsa:10963 STIP1; stress-induced phosphoprotein 1

hsa04071 Sphingolipid signaling pathway - Homo sapiens (human) (17)

cpd:C00346 Ethanolamine phosphate
cpd:C00533 Nitric oxide
cpd:C16845 Peroxynitrite
hsa:134 ADORA1; adenosine A1 receptor
hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53

hsa04210 Apoptosis - Homo sapiens (human) (17)

hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:54205 CYCS; cytochrome c, somatic
hsa:355 FAS; Fas cell surface death receptor
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3562 IL3; interleukin 3
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7157 TP53; tumor protein p53

hsa05212 Pancreatic cancer - Homo sapiens (human) (17)

hsa:598 BCL2L1; BCL2-like 1
hsa:1950 EGF; epidermal growth factor
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7157 TP53; tumor protein p53
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04390 Hippo signaling pathway - Homo sapiens (human) (17)

hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:655 BMP7; bone morphogenetic protein 7
hsa:656 BMP8B; bone morphogenetic protein 8b
hsa:1490 CTGF; connective tissue growth factor
hsa:1742 DLG4; discs, large homolog 4 (Drosophila)
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa:4092 SMAD7; SMAD family member 7
hsa:6657 SOX2; SRY (sex determining region Y)-box 2
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa02010 ABC transporters - Homo sapiens (human) (17)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00114 Choline
cpd:C00123 L-Leucine
cpd:C00135 L-Histidine
cpd:C00137 myo-Inositol
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine
cpd:C01177 Inositol 1-phosphate
hsa:340273 ABCB5; ATP-binding cassette, sub-family B (MDR/TAP), member 5 (EC:3.6.3.44)
hsa:89845 ABCC10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10
hsa:1244 ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2

hsa04978 Mineral absorption - Homo sapiens (human) (16)

cpd:C00037 Glycine
cpd:C00041 L-Alanine
cpd:C00064 L-Glutamine
cpd:C00079 L-Phenylalanine
cpd:C00123 L-Leucine
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:2495 FTH1; ferritin, heavy polypeptide 1 (EC:1.16.3.1)
hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3)
hsa:4489 MT1A; metallothionein 1A
hsa:4495 MT1G; metallothionein 1G
hsa:4501 MT1X; metallothionein 1X
hsa:4502 MT2A; metallothionein 2A

hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) (16)

hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3624 INHBA; inhibin, beta A
hsa:3626 INHBC; inhibin, beta C
hsa:83729 INHBE; inhibin, beta E
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5080 PAX6; paired box 6
hsa:6657 SOX2; SRY (sex determining region Y)-box 2
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa04064 NF-kappa B signaling pathway - Homo sapiens (human) (16)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3553 IL1B; interleukin 1, beta
hsa:51135 IRAK4; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:142 PARP1; poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa04020 Calcium signaling pathway - Homo sapiens (human) (16)

hsa:135 ADORA2A; adenosine A2a receptor
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:489 ATP2A3; ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)
hsa:1910 EDNRB; endothelin receptor type B
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3356 HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:10105 PPIF; peptidylprolyl isomerase F (EC:5.2.1.8)
hsa:6261 RYR1; ryanodine receptor 1 (skeletal)
hsa:6263 RYR3; ryanodine receptor 3
hsa:292 SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
hsa:293 SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
hsa:7416 VDAC1; voltage-dependent anion channel 1
hsa:7417 VDAC2; voltage-dependent anion channel 2

hsa05210 Colorectal cancer - Homo sapiens (human) (16)

hsa:581 BAX; BCL2-associated X protein
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:54205 CYCS; cytochrome c, somatic
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7157 TP53; tumor protein p53

hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human) (16)

hsa:598 BCL2L1; BCL2-like 1
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1649 DDIT3; DNA-damage-inducible transcript 3
hsa:8968 HIST1H3F; histone cluster 1, H3f
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3486 IGFBP3; insulin-like growth factor binding protein 3
hsa:3562 IL3; interleukin 3
hsa:4208 MEF2C; myocyte enhancer factor 2C
hsa:4298 MLLT1; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4804 NGFR; nerve growth factor receptor
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:5077 PAX3; paired box 3
hsa:5079 PAX5; paired box 5
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7157 TP53; tumor protein p53

hsa05146 Amoebiasis - Homo sapiens (human) (16)

cpd:C00533 Nitric oxide
hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:5269 SERPINB6; serpin peptidase inhibitor, clade B (ovalbumin), member 6
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor

hsa04520 Adherens junction - Homo sapiens (human) (15)

hsa:52 ACP1; acid phosphatase 1, soluble (EC:3.1.3.2 3.1.3.48)
hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)

hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human) (15)

hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3596 IL13; interleukin 13
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:3725 JUN; jun proto-oncogene
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor

hsa04110 Cell cycle - Homo sapiens (human) (15)

hsa:891 CCNB1; cyclin B1
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:1647 GADD45A; growth arrest and DNA-damage-inducible, alpha
hsa:4175 MCM6; minichromosome maintenance complex component 6 (EC:3.6.4.12)
hsa:5591 PRKDC; protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:9126 SMC3; structural maintenance of chromosomes 3
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7157 TP53; tumor protein p53
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa04612 Antigen processing and presentation - Homo sapiens (human) (15)

hsa:567 B2M; beta-2-microglobulin
hsa:811 CALR; calreticulin
hsa:821 CANX; calnexin
hsa:925 CD8A; CD8a molecule
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1508 CTSB; cathepsin B (EC:3.4.22.1)
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3308 HSPA4; heat shock 70kDa protein 4
hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3458 IFNG; interferon, gamma
hsa:2923 PDIA3; protein disulfide isomerase family A, member 3 (EC:5.3.4.1)
hsa:7124 TNF; tumor necrosis factor

hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human) (15)

cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00041 L-Alanine
cpd:C00042 Succinate
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
cpd:C01042 N-Acetyl-L-aspartate
hsa:440 ASNS; asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)
hsa:790 CAD; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5)
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)

hsa04540 Gap junction - Homo sapiens (human) (15)

cpd:C00025 L-Glutamate
cpd:C00533 Nitric oxide
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1813 DRD2; dopamine receptor D2
hsa:1950 EGF; epidermal growth factor
hsa:2697 GJA1; gap junction protein, alpha 1, 43kDa
hsa:57369 GJD2; gap junction protein, delta 2, 36kDa
hsa:3356 HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:10376 TUBA1B; tubulin, alpha 1b

hsa00620 Pyruvate metabolism - Homo sapiens (human) (15)

cpd:C00022 Pyruvate
cpd:C00033 Acetate
cpd:C00042 Succinate
cpd:C00058 Formate
cpd:C00186 (S)-Lactate
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:55902 ACSS2; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1)
hsa:1737 DLAT; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)

hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human) (15)

cpd:C00123 L-Leucine
cpd:C00183 L-Valine
cpd:C00407 L-Isoleucine
hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16)
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:549 AUH; AU RNA binding protein/enoyl-CoA hydratase (EC:4.2.1.18)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4)
hsa:3155 HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4)
hsa:3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)
hsa:5019 OXCT1; 3-oxoacid CoA transferase 1 (EC:2.8.3.5)

hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human) (15)

cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00042 Succinate
cpd:C00058 Formate
cpd:C00064 L-Glutamine
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)

hsa03040 Spliceosome - Homo sapiens (human) (15)

hsa:3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1
hsa:220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3
hsa:3183 HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2)
hsa:3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
hsa:4670 HNRNPM; heterogeneous nuclear ribonucleoprotein M
hsa:3192 HNRNPU; heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:27316 RBMX; RNA binding motif protein, X-linked
hsa:23451 SF3B1; splicing factor 3b, subunit 1, 155kDa
hsa:23020 SNRNP200; small nuclear ribonucleoprotein 200kDa (U5) (EC:3.6.4.13)
hsa:6625 SNRNP70; small nuclear ribonucleoprotein 70kDa (U1)
hsa:6631 SNRPC; small nuclear ribonucleoprotein polypeptide C
hsa:10929 SRSF8; serine/arginine-rich splicing factor 8
hsa:7307 U2AF1; U2 small nuclear RNA auxiliary factor 1

hsa04660 T cell receptor signaling pathway - Homo sapiens (human) (15)

hsa:925 CD8A; CD8a molecule
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3458 IFNG; interferon, gamma
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3586 IL10; interleukin 10
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:7124 TNF; tumor necrosis factor

hsa03013 RNA transport - Homo sapiens (human) (14)

hsa:23191 CYFIP1; cytoplasmic FMR1 interacting protein 1
hsa:1915 EEF1A1; eukaryotic translation elongation factor 1 alpha 1
hsa:1965 EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
hsa:8894 EIF2S2; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
hsa:8662 EIF3B; eukaryotic translation initiation factor 3, subunit B
hsa:8667 EIF3H; eukaryotic translation initiation factor 3, subunit H
hsa:1973 EIF4A1; eukaryotic translation initiation factor 4A1 (EC:3.6.4.13)
hsa:60528 ELAC2; elaC ribonuclease Z 2 (EC:3.1.26.11)
hsa:26986 PABPC1; poly(A) binding protein, cytoplasmic 1
hsa:5901 RAN; RAN, member RAS oncogene family
hsa:6613 SUMO2; small ubiquitin-like modifier 2
hsa:7175 TPR; translocated promoter region, nuclear basket protein
hsa:7514 XPO1; exportin 1
hsa:57510 XPO5; exportin 5

hsa04310 Wnt signaling pathway - Homo sapiens (human) (14)

hsa:27101 CACYBP; calcyclin binding protein
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:1487 CTBP1; C-terminal binding protein 1
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:3725 JUN; jun proto-oncogene
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:7157 TP53; tumor protein p53
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa04360 Axon guidance - Homo sapiens (human) (14)

hsa:3983 ABLIM1; actin binding LIM protein 1
hsa:1072 CFL1; cofilin 1 (non-muscle)
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:1808 DPYSL2; dihydropyrimidinase-like 2
hsa:56896 DPYSL5; dihydropyrimidinase-like 5
hsa:1947 EFNB1; ephrin-B1
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:8829 NRP1; neuropilin 1
hsa:9423 NTN1; netrin 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6091 ROBO1; roundabout guidance receptor 1
hsa:9353 SLIT2; slit guidance ligand 2

hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human) (14)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:652 BMP4; bone morphogenetic protein 4
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:10499 NCOA2; nuclear receptor coactivator 2
hsa:4851 NOTCH1; notch 1
hsa:4853 NOTCH2; notch 2
hsa:7157 TP53; tumor protein p53

hsa04915 Estrogen signaling pathway - Homo sapiens (human) (14)

cpd:C00533 Nitric oxide
hsa:468 ATF4; activating transcription factor 4
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa05220 Chronic myeloid leukemia - Homo sapiens (human) (14)

hsa:598 BCL2L1; BCL2-like 1
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1487 CTBP1; C-terminal binding protein 1
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7046 TGFBR1; transforming growth factor, beta receptor 1 (EC:2.7.11.30)
hsa:7048 TGFBR2; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
hsa:7157 TP53; tumor protein p53

hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human) (14)

hsa:64170 CARD9; caspase recruitment domain family, member 9
hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3553 IL1B; interleukin 1, beta
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:7124 TNF; tumor necrosis factor

hsa04921 Oxytocin signaling pathway - Homo sapiens (human) (14)

cpd:C00533 Nitric oxide
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1938 EEF2; eukaryotic translation elongation factor 2
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4208 MEF2C; myocyte enhancer factor 2C
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:6261 RYR1; ryanodine receptor 1 (skeletal)
hsa:6263 RYR3; ryanodine receptor 3

hsa05030 Cocaine addiction - Homo sapiens (human) (13)

cpd:C00025 L-Glutamate
cpd:C00082 L-Tyrosine
hsa:468 ATF4; activating transcription factor 4
hsa:627 BDNF; brain-derived neurotrophic factor
hsa:8851 CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1742 DLG4; discs, large homolog 4 (Drosophila)
hsa:1813 DRD2; dopamine receptor D2
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3725 JUN; jun proto-oncogene
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5173 PDYN; prodynorphin
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human) (13)

hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:355 FAS; Fas cell surface death receptor
hsa:3440 IFNA2; interferon, alpha 2
hsa:3454 IFNAR1; interferon (alpha, beta and omega) receptor 1
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3458 IFNG; interferon, gamma
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5551 PRF1; perforin 1 (pore forming protein)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7124 TNF; tumor necrosis factor

hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human) (13)

hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:6351 CCL4; chemokine (C-C motif) ligand 4
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:3440 IFNA2; interferon, alpha 2
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3553 IL1B; interleukin 1, beta
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)

hsa05211 Renal cell carcinoma - Homo sapiens (human) (13)

hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:6923 TCEB2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human) (13)

hsa:3627 CXCL10; chemokine (C-X-C motif) ligand 10
hsa:3440 IFNA2; interferon, alpha 2
hsa:3456 IFNB1; interferon, beta 1, fibroblast
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3661 IRF3; interferon regulatory factor 3
hsa:3665 IRF7; interferon regulatory factor 7
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:57506 MAVS; mitochondrial antiviral signaling protein
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:29110 TBK1; TANK-binding kinase 1 (EC:2.7.11.1)
hsa:7124 TNF; tumor necrosis factor

hsa05131 Shigellosis - Homo sapiens (human) (13)

hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:2017 CTTN; cortactin
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5216 PFN1; profilin 1
hsa:5217 PFN2; profilin 2
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7307 U2AF1; U2 small nuclear RNA auxiliary factor 1

hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human) (12)

cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00049 L-Aspartate
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00123 L-Leucine
cpd:C00183 L-Valine
cpd:C00407 L-Isoleucine
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:3419 IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)

hsa04725 Cholinergic synapse - Homo sapiens (human) (12)

cpd:C00033 Acetate
cpd:C00114 Choline
hsa:43 ACHE; acetylcholinesterase (Yt blood group) (EC:3.1.1.7)
hsa:468 ATF4; activating transcription factor 4
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:1103 CHAT; choline O-acetyltransferase (EC:2.3.1.6)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:6572 SLC18A3; solute carrier family 18 (vesicular acetylcholine transporter), member 3

hsa00640 Propanoate metabolism - Homo sapiens (human) (12)

cpd:C00033 Acetate
cpd:C00042 Succinate
cpd:C00186 (S)-Lactate
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:55902 ACSS2; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)

hsa05323 Rheumatoid arthritis - Homo sapiens (human) (12)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3458 IFNG; interferon, gamma
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3725 JUN; jun proto-oncogene
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04931 Insulin resistance - Homo sapiens (human) (12)

cpd:C00022 Pyruvate
cpd:C00533 Nitric oxide
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:5836 PYGL; phosphorylase, glycogen, liver (EC:2.4.1.1)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A

hsa00330 Arginine and proline metabolism - Homo sapiens (human) (12)

cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00300 Creatine
cpd:C00533 Nitric oxide
hsa:5832 ALDH18A1; aldehyde dehydrogenase 18 family, member A1 (EC:1.2.1.41 2.7.2.11)
hsa:1158 CKM; creatine kinase, muscle (EC:2.7.3.2)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:4942 OAT; ornithine aminotransferase (EC:2.6.1.13)

hsa04115 p53 signaling pathway - Homo sapiens (human) (12)

hsa:581 BAX; BCL2-associated X protein
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:891 CCNB1; cyclin B1
hsa:900 CCNG1; cyclin G1
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:54205 CYCS; cytochrome c, somatic
hsa:355 FAS; Fas cell surface death receptor
hsa:1647 GADD45A; growth arrest and DNA-damage-inducible, alpha
hsa:3486 IGFBP3; insulin-like growth factor binding protein 3
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa:7157 TP53; tumor protein p53

hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human) (12)

cpd:C00014 Ammonia
cpd:C00022 Pyruvate
cpd:C00037 Glycine
cpd:C00049 L-Aspartate
cpd:C00114 Choline
cpd:C00188 L-Threonine
cpd:C00300 Creatine
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:26227 PHGDH; phosphoglycerate dehydrogenase (EC:1.1.1.95)
hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)

hsa04012 ErbB signaling pathway - Homo sapiens (human) (12)

hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1950 EGF; epidermal growth factor
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:3084 NRG1; neuregulin 1

hsa04916 Melanogenesis - Homo sapiens (human) (12)

cpd:C00082 L-Tyrosine
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:1910 EDNRB; endothelin receptor type B
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5443 POMC; proopiomelanocortin
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human) (12)


hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:1072 CFL1; cofilin 1 (non-muscle)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4082 MARCKS; myristoylated alanine-rich protein kinase C substrate
hsa:65108 MARCKSL1; MARCKS-like 1
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04922 Glucagon signaling pathway - Homo sapiens (human) (12)

cpd:C00022 Pyruvate
cpd:C00042 Succinate
cpd:C00186 (S)-Lactate
hsa:468 ATF4; activating transcription factor 4
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:5223 PGAM1; phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)
hsa:5836 PYGL; phosphorylase, glycogen, liver (EC:2.4.1.1)

hsa01212 Fatty acid metabolism - Homo sapiens (human) (12)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16)
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:37 ACADVL; acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:1376 CPT2; carnitine palmitoyltransferase 2 (EC:2.3.1.21)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:79071 ELOVL6; ELOVL fatty acid elongase 6 (EC:2.3.1.199)
hsa:2194 FASN; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:51102 MECR; mitochondrial trans-2-enoyl-CoA reductase (EC:1.3.1.38)
hsa:9524 TECR; trans-2,3-enoyl-CoA reductase (EC:1.3.1.93)

hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human) (12)

cpd:C00022 Pyruvate
cpd:C00042 Succinate
hsa:50 ACO2; aconitase 2, mitochondrial (EC:4.2.1.3)
hsa:1737 DLAT; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)
hsa:1738 DLD; dihydrolipoamide dehydrogenase (EC:1.8.1.4)
hsa:1743 DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61)
hsa:2271 FH; fumarate hydratase (EC:4.2.1.2)
hsa:3419 IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
hsa:5160 PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1)
hsa:6389 SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)

hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human) (11)

hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:859 CAV3; caveolin 3
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:2017 CTTN; cortactin
hsa:1759 DNM1; dynamin 1 (EC:3.6.5.5)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:55752 SEPT11; septin 11
hsa:23176 SEPT8; septin 8
hsa:10801 SEPT9; septin 9

hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human) (11)

cpd:C00547 L-Noradrenaline
hsa:468 ATF4; activating transcription factor 4
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7169 TPM2; tropomyosin 2 (beta)
hsa:7170 TPM3; tropomyosin 3

hsa00270 Cysteine and methionine metabolism - Homo sapiens (human) (11)

cpd:C00022 Pyruvate
cpd:C00041 L-Alanine
cpd:C00049 L-Aspartate
hsa:191 AHCY; adenosylhomocysteinase (EC:3.3.1.1)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:3939 LDHA; lactate dehydrogenase A (EC:1.1.1.27)
hsa:3945 LDHB; lactate dehydrogenase B (EC:1.1.1.27)
hsa:4144 MAT2A; methionine adenosyltransferase II, alpha (EC:2.5.1.6)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:4191 MDH2; malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)

hsa04114 Oocyte meiosis - Homo sapiens (human) (11)

hsa:891 CCNB1; cyclin B1
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:9126 SMC3; structural maintenance of chromosomes 3
hsa:7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa05231 Choline metabolism in cancer - Homo sapiens (human) (11)

cpd:C00114 Choline
hsa:1950 EGF; epidermal growth factor
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04721 Synaptic vesicle cycle - Homo sapiens (human) (11)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:10815 CPLX1; complexin 1
hsa:1759 DNM1; dynamin 1 (EC:3.6.5.5)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:4905 NSF; N-ethylmaleimide-sensitive factor (EC:3.6.4.6)
hsa:6572 SLC18A3; solute carrier family 18 (vesicular acetylcholine transporter), member 3
hsa:6812 STXBP1; syntaxin binding protein 1

hsa00220 Arginine biosynthesis - Homo sapiens (human) (11)

cpd:C00014 Ammonia
cpd:C00025 L-Glutamate
cpd:C00049 L-Aspartate
cpd:C00064 L-Glutamine
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)

hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human) (11)

hsa:3596 IL13; interleukin 13
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7124 TNF; tumor necrosis factor

hsa04726 Serotonergic synapse - Homo sapiens (human) (11)

cpd:C00780 Serotonin
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:3350 HTR1A; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
hsa:3351 HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
hsa:3355 HTR1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
hsa:3356 HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa05134 Legionellosis - Homo sapiens (human) (11)

hsa:834 CASP1; caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:54205 CYCS; cytochrome c, somatic
hsa:1915 EEF1A1; eukaryotic translation elongation factor 1 alpha 1
hsa:3303 HSPA1A; heat shock 70kDa protein 1A
hsa:3312 HSPA8; heat shock 70kDa protein 8
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:7124 TNF; tumor necrosis factor

hsa05330 Allograft rejection - Homo sapiens (human) (10)

cpd:C00533 Nitric oxide
hsa:355 FAS; Fas cell surface death receptor
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:5551 PRF1; perforin 1 (pore forming protein)
hsa:7124 TNF; tumor necrosis factor

hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human) (10)

cpd:C00014 Ammonia
cpd:C00025 L-Glutamate
cpd:C00064 L-Glutamine
cpd:C00267 alpha-D-Glucose
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:4190 MDH1; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96)
hsa:1468 SLC25A10; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10

hsa04940 Type I diabetes mellitus - Homo sapiens (human) (10)

cpd:C00533 Nitric oxide
hsa:355 FAS; Fas cell surface death receptor
hsa:3458 IFNG; interferon, gamma
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:5551 PRF1; perforin 1 (pore forming protein)
hsa:7124 TNF; tumor necrosis factor

hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human) (10)

hsa:891 CCNB1; cyclin B1
hsa:983 CDK1; cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)
hsa:3320 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1
hsa:3326 HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)

hsa04720 Long-term potentiation - Homo sapiens (human) (10)

cpd:C00025 L-Glutamate
hsa:468 ATF4; activating transcription factor 4
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)

hsa04713 Circadian entrainment - Homo sapiens (human) (10)

cpd:C00025 L-Glutamate
cpd:C00533 Nitric oxide
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:6261 RYR1; ryanodine receptor 1 (skeletal)
hsa:6263 RYR3; ryanodine receptor 3

hsa04917 Prolactin signaling pathway - Homo sapiens (human) (10)

cpd:C00082 L-Tyrosine
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa04727 GABAergic synapse - Homo sapiens (human) (10)

cpd:C00025 L-Glutamate
cpd:C00042 Succinate
cpd:C00064 L-Glutamine
hsa:11337 GABARAP; GABA(A) receptor-associated protein
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:4905 NSF; N-ethylmaleimide-sensitive factor (EC:3.6.4.6)

hsa00650 Butanoate metabolism - Homo sapiens (human) (10)

cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00042 Succinate
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:3155 HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4)
hsa:3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)
hsa:5019 OXCT1; 3-oxoacid CoA transferase 1 (EC:2.8.3.5)

hsa05144 Malaria - Homo sapiens (human) (10)

cpd:C00533 Nitric oxide
hsa:6347 CCL2; chemokine (C-C motif) ligand 2
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3553 IL1B; interleukin 1, beta
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa00350 Tyrosine metabolism - Homo sapiens (human) (10)

cpd:C00022 Pyruvate
cpd:C00042 Succinate
cpd:C00082 L-Tyrosine
cpd:C00547 L-Noradrenaline
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:4282 MIF; macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)
hsa:5409 PNMT; phenylethanolamine N-methyltransferase (EC:2.1.1.28)
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa00480 Glutathione metabolism - Homo sapiens (human) (10)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
hsa:79017 GGCT; gamma-glutamylcyclotransferase (EC:2.3.2.4)
hsa:2876 GPX1; glutathione peroxidase 1 (EC:1.11.1.9)
hsa:2947 GSTM3; glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)
hsa:9446 GSTO1; glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2)
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:2952 GSTT1; glutathione S-transferase theta 1 (EC:2.5.1.18)
hsa:51056 LAP3; leucine aminopeptidase 3 (EC:3.4.11.5 3.4.11.1)
hsa:5226 PGD; phosphogluconate dehydrogenase (EC:1.1.1.44)

hsa04724 Glutamatergic synapse - Homo sapiens (human) (10)

cpd:C00025 L-Glutamate
cpd:C00064 L-Glutamine
hsa:1742 DLG4; discs, large homolog 4 (Drosophila)
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)
hsa:2898 GRIK2; glutamate receptor, ionotropic, kainate 2
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:6511 SLC1A6; solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

hsa04530 Tight junction - Homo sapiens (human) (10)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:2017 CTTN; cortactin
hsa:4627 MYH9; myosin, heavy chain 9, non-muscle
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:6709 SPTAN1; spectrin, alpha, non-erythrocytic 1
hsa:8531 YBX3; Y box binding protein 3

hsa04072 Phospholipase D signaling pathway - Homo sapiens (human) (9)

cpd:C00025 L-Glutamate
hsa:1759 DNM1; dynamin 1 (EC:3.6.5.5)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:1950 EGF; epidermal growth factor
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)

hsa05031 Amphetamine addiction - Homo sapiens (human) (9)

cpd:C00025 L-Glutamate
cpd:C00082 L-Tyrosine
hsa:468 ATF4; activating transcription factor 4
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1
hsa:3725 JUN; jun proto-oncogene
hsa:5173 PDYN; prodynorphin
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa04730 Long-term depression - Homo sapiens (human) (9)

cpd:C00025 L-Glutamate
cpd:C00533 Nitric oxide
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:6261 RYR1; ryanodine receptor 1 (skeletal)

hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human) (9)

cpd:C00780 Serotonin
cpd:C11695 Anandamide
hsa:3356 HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
hsa:3553 IL1B; interleukin 1, beta
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4803 NGF; nerve growth factor (beta polypeptide)
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:79054 TRPM8; transient receptor potential cation channel, subfamily M, member 8

hsa03050 Proteasome - Homo sapiens (human) (9)

hsa:3458 IFNG; interferon, gamma
hsa:5684 PSMA3; proteasome (prosome, macropain) subunit, alpha type, 3 (EC:3.4.25.1)
hsa:5688 PSMA7; proteasome (prosome, macropain) subunit, alpha type, 7 (EC:3.4.25.1)
hsa:5691 PSMB3; proteasome (prosome, macropain) subunit, beta type, 3 (EC:3.4.25.1)
hsa:5706 PSMC6; proteasome (prosome, macropain) 26S subunit, ATPase, 6
hsa:5707 PSMD1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
hsa:5718 PSMD12; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
hsa:5710 PSMD4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
hsa:5713 PSMD7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

hsa04370 VEGF signaling pathway - Homo sapiens (human) (9)

cpd:C00533 Nitric oxide
hsa:3791 KDR; kinase insert domain receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04912 GnRH signaling pathway - Homo sapiens (human) (9)

hsa:468 ATF4; activating transcription factor 4
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5609 MAP2K7; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)

hsa04211 Longevity regulating pathway - mammal - Homo sapiens (human) (9)

cpd:C00003 NAD+
hsa:468 ATF4; activating transcription factor 4
hsa:581 BAX; BCL2-associated X protein
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1)
hsa:7157 TP53; tumor protein p53

hsa04330 Notch signaling pathway - Homo sapiens (human) (9)

hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86)
hsa:1387 CREBBP; CREB binding protein (EC:2.3.1.48)
hsa:1487 CTBP1; C-terminal binding protein 1
hsa:28514 DLL1; delta-like 1 (Drosophila)
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:2033 EP300; E1A binding protein p300 (EC:2.3.1.48)
hsa:3280 HES1; hes family bHLH transcription factor 1
hsa:4851 NOTCH1; notch 1
hsa:4853 NOTCH2; notch 2

hsa05143 African trypanosomiasis - Homo sapiens (human) (9)

cpd:C00533 Nitric oxide
hsa:355 FAS; Fas cell surface death receptor
hsa:3458 IFNG; interferon, gamma
hsa:3586 IL10; interleukin 10
hsa:3592 IL12A; interleukin 12A
hsa:3593 IL12B; interleukin 12B
hsa:3553 IL1B; interleukin 1, beta
hsa:7124 TNF; tumor necrosis factor
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa00230 Purine metabolism - Homo sapiens (human) (9)

cpd:C00014 Ammonia
cpd:C00037 Glycine
cpd:C00064 L-Glutamine
hsa:2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (EC:2.1.2.2 6.3.3.1 6.3.4.13)
hsa:3615 IMPDH2; IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205)
hsa:5139 PDE3A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:87178 PNPT1; polyribonucleotide nucleotidyltransferase 1 (EC:2.7.7.8)
hsa:221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)

hsa04920 Adipocytokine signaling pathway - Homo sapiens (human) (9)

hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4852 NPY; neuropeptide Y
hsa:5443 POMC; proopiomelanocortin
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
hsa:7124 TNF; tumor necrosis factor
hsa:7132 TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
hsa:7133 TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B

hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) (9)

cpd:C00014 Ammonia
hsa:6868 ADAM17; ADAM metallopeptidase domain 17 (EC:3.4.24.86)
hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:6352 CCL5; chemokine (C-C motif) ligand 5
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3725 JUN; jun proto-oncogene
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human) (9)

cpd:C00025 L-Glutamate
cpd:C11695 Anandamide
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa05219 Bladder cancer - Homo sapiens (human) (9)

hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1950 EGF; epidermal growth factor
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7157 TP53; tumor protein p53
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04910 Insulin signaling pathway - Homo sapiens (human) (9)

hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2194 FASN; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5836 PYGL; phosphorylase, glycogen, liver (EC:2.4.1.1)

hsa04662 B cell receptor signaling pathway - Homo sapiens (human) (9)

hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:3725 JUN; jun proto-oncogene
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa05218 Melanoma - Homo sapiens (human) (9)

hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1950 EGF; epidermal growth factor
hsa:2247 FGF2; fibroblast growth factor 2 (basic)
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7157 TP53; tumor protein p53

hsa00071 Fatty acid degradation - Homo sapiens (human) (8)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16)
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:37 ACADVL; acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:1376 CPT2; carnitine palmitoyltransferase 2 (EC:2.3.1.21)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)

hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human) (8)

hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:4000 LMNA; lamin A/C
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7169 TPM2; tropomyosin 2 (beta)
hsa:7170 TPM3; tropomyosin 3

hsa04728 Dopaminergic synapse - Homo sapiens (human) (8)

cpd:C00082 L-Tyrosine
hsa:468 ATF4; activating transcription factor 4
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1813 DRD2; dopamine receptor D2
hsa:1814 DRD3; dopamine receptor D3
hsa:2353 FOS; FBJ murine osteosarcoma viral oncogene homolog
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:7054 TH; tyrosine hydroxylase (EC:1.14.16.2)

hsa04640 Hematopoietic cell lineage - Homo sapiens (human) (8)

hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:925 CD8A; CD8a molecule
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:7124 TNF; tumor necrosis factor

hsa00460 Cyanoamino acid metabolism - Homo sapiens (human) (8)

cpd:C00014 Ammonia
cpd:C00037 Glycine
cpd:C00049 L-Aspartate
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
cpd:C00183 L-Valine
cpd:C00407 L-Isoleucine
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)

hsa05332 Graft-versus-host disease - Homo sapiens (human) (8)

cpd:C00533 Nitric oxide
hsa:355 FAS; Fas cell surface death receptor
hsa:3458 IFNG; interferon, gamma
hsa:3552 IL1A; interleukin 1, alpha
hsa:3553 IL1B; interleukin 1, beta
hsa:3558 IL2; interleukin 2
hsa:5551 PRF1; perforin 1 (pore forming protein)
hsa:7124 TNF; tumor necrosis factor

hsa05222 Small cell lung cancer - Homo sapiens (human) (8)

hsa:596 BCL2; B-cell CLL/lymphoma 2
hsa:598 BCL2L1; BCL2-like 1
hsa:54205 CYCS; cytochrome c, somatic
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:7157 TP53; tumor protein p53

hsa05216 Thyroid cancer - Homo sapiens (human) (8)

hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4914 NTRK1; neurotrophic tyrosine kinase, receptor, type 1 (EC:2.7.10.1)
hsa:7157 TP53; tumor protein p53
hsa:7170 TPM3; tropomyosin 3
hsa:7175 TPR; translocated promoter region, nuclear basket protein

hsa04742 Taste transduction - Homo sapiens (human) (8)

cpd:C00025 L-Glutamate
cpd:C00547 L-Noradrenaline
cpd:C00780 Serotonin
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:3350 HTR1A; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
hsa:3351 HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
hsa:3355 HTR1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled

hsa04670 Leukocyte transendothelial migration - Homo sapiens (human) (8)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:7430 EZR; ezrin
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) (8)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:793 CALB1; calbindin 1, 28kDa
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:1759 DNM1; dynamin 1 (EC:3.6.5.5)
hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)
hsa:3816 KLK1; kallikrein 1 (EC:3.4.21.35)
hsa:8766 RAB11A; RAB11A, member RAS oncogene family

hsa00030 Pentose phosphate pathway - Homo sapiens (human) (8)

cpd:C00022 Pyruvate
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:5226 PGD; phosphogluconate dehydrogenase (EC:1.1.1.44)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)
hsa:6888 TALDO1; transaldolase 1 (EC:2.2.1.2)
hsa:7086 TKT; transketolase (EC:2.2.1.1)

hsa00360 Phenylalanine metabolism - Homo sapiens (human) (8)

cpd:C00022 Pyruvate
cpd:C00042 Succinate
cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:4282 MIF; macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)

hsa05213 Endometrial cancer - Homo sapiens (human) (8)

hsa:1950 EGF; epidermal growth factor
hsa:2002 ELK1; ELK1, member of ETS oncogene family
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7157 TP53; tumor protein p53

hsa04918 Thyroid hormone synthesis - Homo sapiens (human) (8)

hsa:468 ATF4; activating transcription factor 4
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:821 CANX; calnexin
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:2876 GPX1; glutathione peroxidase 1 (EC:1.11.1.9)
hsa:7184 HSP90B1; heat shock protein 90kDa beta (Grp94), member 1
hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human) (8)

hsa:359 AQP2; aquaporin 2 (collecting duct)
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:10540 DCTN2; dynactin 2 (p50)
hsa:1778 DYNC1H1; dynein, cytoplasmic 1, heavy chain 1
hsa:4905 NSF; N-ethylmaleimide-sensitive factor (EC:3.6.4.6)
hsa:8766 RAB11A; RAB11A, member RAS oncogene family
hsa:9230 RAB11B; RAB11B, member RAS oncogene family
hsa:5868 RAB5A; RAB5A, member RAS oncogene family

hsa05414 Dilated cardiomyopathy - Homo sapiens (human) (8)

hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:4000 LMNA; lamin A/C
hsa:7040 TGFB1; transforming growth factor, beta 1
hsa:7042 TGFB2; transforming growth factor, beta 2
hsa:7124 TNF; tumor necrosis factor
hsa:7169 TPM2; tropomyosin 2 (beta)
hsa:7170 TPM3; tropomyosin 3

hsa05214 Glioma - Homo sapiens (human) (8)

hsa:1026 CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa:1950 EGF; epidermal growth factor
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7157 TP53; tumor protein p53

hsa05223 Non-small cell lung cancer - Homo sapiens (human) (8)

hsa:238 ALK; anaplastic lymphoma receptor tyrosine kinase (EC:2.7.10.1)
hsa:1950 EGF; epidermal growth factor
hsa:2064 ERBB2; erb-b2 receptor tyrosine kinase 2 (EC:2.7.10.1)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7157 TP53; tumor protein p53

hsa04270 Vascular smooth muscle contraction - Homo sapiens (human) (8)

cpd:C00533 Nitric oxide
cpd:C00547 L-Noradrenaline
hsa:135 ADORA2A; adenosine A2a receptor
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)

hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human) (8)

hsa:1457 CSNK2A1; casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)
hsa:1459 CSNK2A2; casein kinase 2, alpha prime polypeptide (EC:2.7.11.1)
hsa:1460 CSNK2B; casein kinase 2, beta polypeptide (EC:2.7.11.1)
hsa:23195 MDN1; midasin AAA ATPase 1
hsa:5901 RAN; RAN, member RAS oncogene family
hsa:6949 TCOF1; Treacher Collins-Franceschetti syndrome 1
hsa:84128 WDR75; WD repeat domain 75
hsa:7514 XPO1; exportin 1

hsa04976 Bile secretion - Homo sapiens (human) (7)

cpd:C00114 Choline
cpd:C00187 Cholesterol
cpd:C00780 Serotonin
hsa:1244 ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:3949 LDLR; low density lipoprotein receptor

hsa00310 Lysine degradation - Homo sapiens (human) (7)

cpd:C00037 Glycine
hsa:10157 AASS; aminoadipate-semialdehyde synthase (EC:1.5.1.8 1.5.1.9)
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:1743 DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)

hsa00062 Fatty acid elongation - Homo sapiens (human) (7)

hsa:10449 ACAA2; acetyl-CoA acyltransferase 2 (EC:2.3.1.16)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:79071 ELOVL6; ELOVL fatty acid elongase 6 (EC:2.3.1.199)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:51102 MECR; mitochondrial trans-2-enoyl-CoA reductase (EC:1.3.1.38)
hsa:9524 TECR; trans-2,3-enoyl-CoA reductase (EC:1.3.1.93)

hsa04972 Pancreatic secretion - Homo sapiens (human) (7)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:489 ATP2A3; ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)
hsa:1357 CPA1; carboxypeptidase A1 (pancreatic) (EC:3.4.17.1)
hsa:8766 RAB11A; RAB11A, member RAS oncogene family
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04145 Phagosome - Homo sapiens (human) (7)

hsa:811 CALR; calreticulin
hsa:821 CANX; calnexin
hsa:1778 DYNC1H1; dynein, cytoplasmic 1, heavy chain 1
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:5868 RAB5A; RAB5A, member RAS oncogene family
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa:10376 TUBA1B; tubulin, alpha 1b

hsa05221 Acute myeloid leukemia - Homo sapiens (human) (7)

hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5605 MAP2K2; mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4790 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa:6774 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)

hsa05217 Basal cell carcinoma - Homo sapiens (human) (7)

cpd:C00187 Cholesterol
hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:1857 DVL3; dishevelled segment polarity protein 3
hsa:6469 SHH; sonic hedgehog
hsa:7157 TP53; tumor protein p53
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa04672 Intestinal immune network for IgA production - Homo sapiens (human) (7)

hsa:6387 CXCL12; chemokine (C-X-C motif) ligand 12
hsa:7852 CXCR4; chemokine (C-X-C motif) receptor 4
hsa:3586 IL10; interleukin 10
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:7040 TGFB1; transforming growth factor, beta 1

hsa04152 AMPK signaling pathway - Homo sapiens (human) (7)

cpd:C00003 NAD+
cpd:C00022 Pyruvate
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1938 EEF2; eukaryotic translation elongation factor 2
hsa:2194 FASN; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:9230 RAB11B; RAB11B, member RAS oncogene family

hsa04146 Peroxisome - Homo sapiens (human) (7)

hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:3155 HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4)
hsa:3295 HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12)
hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)
hsa:5052 PRDX1; peroxiredoxin 1 (EC:1.11.1.15)
hsa:6647 SOD1; superoxide dismutase 1, soluble (EC:1.15.1.1)
hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1)

hsa05204 Chemical carcinogenesis - Homo sapiens (human) (7)

hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:2947 GSTM3; glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)
hsa:9446 GSTO1; glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2)
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:2952 GSTT1; glutathione S-transferase theta 1 (EC:2.5.1.18)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00910 Nitrogen metabolism - Homo sapiens (human) (7)

cpd:C00014 Ammonia
cpd:C00025 L-Glutamate
cpd:C00058 Formate
cpd:C00064 L-Glutamine
cpd:C00533 Nitric oxide
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)
hsa:2752 GLUL; glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2)

hsa04260 Cardiac muscle contraction - Homo sapiens (human) (7)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:1327 COX4I1; cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)
hsa:1347 COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)
hsa:7169 TPM2; tropomyosin 2 (beta)
hsa:7170 TPM3; tropomyosin 3

hsa00410 beta-Alanine metabolism - Homo sapiens (human) (7)

cpd:C00049 L-Aspartate
cpd:C00135 L-Histidine
hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4)

hsa04930 Type II diabetes mellitus - Homo sapiens (human) (7)

cpd:C00022 Pyruvate
hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:5599 MAPK8; mitogen-activated protein kinase 8 (EC:2.7.11.24)
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)
hsa:7124 TNF; tumor necrosis factor

hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human) (7)

hsa:10109 ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa
hsa:10094 ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa
hsa:2017 CTTN; cortactin
hsa:7430 EZR; ezrin
hsa:4691 NCL; nucleolin
hsa:10376 TUBA1B; tubulin, alpha 1b
hsa:10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human) (6)

cpd:C00003 NAD+
cpd:C00187 Cholesterol
hsa:468 ATF4; activating transcription factor 4
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:3949 LDLR; low density lipoprotein receptor
hsa:5581 PRKCE; protein kinase C, epsilon (EC:2.7.11.13)

hsa04924 Renin secretion - Homo sapiens (human) (6)

cpd:C00533 Nitric oxide
cpd:C00547 L-Noradrenaline
hsa:134 ADORA1; adenosine A1 receptor
hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:1508 CTSB; cathepsin B (EC:3.4.22.1)
hsa:5139 PDE3A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17)

hsa00380 Tryptophan metabolism - Homo sapiens (human) (6)

cpd:C00780 Serotonin
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:847 CAT; catalase (EC:1.11.1.6)
hsa:1892 ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17)
hsa:3033 HADH; hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)

hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human) (6)

hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:2947 GSTM3; glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)
hsa:9446 GSTO1; glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2)
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:2952 GSTT1; glutathione S-transferase theta 1 (EC:2.5.1.18)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human) (6)

cpd:C00025 L-Glutamate
cpd:C00037 Glycine
cpd:C00188 L-Threonine
hsa:644 BLVRA; biliverdin reductase A (EC:1.3.1.24)
hsa:3162 HMOX1; heme oxygenase 1 (EC:1.14.99.3)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa04970 Salivary secretion - Homo sapiens (human) (6)

cpd:C00533 Nitric oxide
cpd:C00547 L-Noradrenaline
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)
hsa:6263 RYR3; ryanodine receptor 3

hsa04150 mTOR signaling pathway - Homo sapiens (human) (6)

hsa:3551 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:6195 RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
hsa:7124 TNF; tumor necrosis factor
hsa:7422 VEGFA; vascular endothelial growth factor A

hsa00564 Glycerophospholipid metabolism - Homo sapiens (human) (6)

cpd:C00114 Choline
cpd:C00346 Ethanolamine phosphate
hsa:43 ACHE; acetylcholinesterase (Yt blood group) (EC:3.1.1.7)
hsa:1103 CHAT; choline O-acetyltransferase (EC:2.3.1.6)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)
hsa:9791 PTDSS1; phosphatidylserine synthase 1 (EC:2.7.8.29)

hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human) (6)

hsa:87 ACTN1; actinin, alpha 1
hsa:81 ACTN4; actinin, alpha 4
hsa:488 ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)
hsa:2697 GJA1; gap junction protein, alpha 1, 43kDa
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:4000 LMNA; lamin A/C

hsa05320 Autoimmune thyroid disease - Homo sapiens (human) (6)

hsa:355 FAS; Fas cell surface death receptor
hsa:3440 IFNA2; interferon, alpha 2
hsa:3586 IL10; interleukin 10
hsa:3558 IL2; interleukin 2
hsa:3565 IL4; interleukin 4
hsa:5551 PRF1; perforin 1 (pore forming protein)

hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) (6)

hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)
hsa:2947 GSTM3; glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)
hsa:9446 GSTO1; glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2)
hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)
hsa:2952 GSTT1; glutathione S-transferase theta 1 (EC:2.5.1.18)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa04610 Complement and coagulation cascades - Homo sapiens (human) (6)

hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:727 C5; complement component 5
hsa:2152 F3; coagulation factor III (thromboplastin, tissue factor)
hsa:3827 KNG1; kininogen 1
hsa:5054 SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

hsa05310 Asthma - Homo sapiens (human) (6)

hsa:6356 CCL11; chemokine (C-C motif) ligand 11
hsa:3586 IL10; interleukin 10
hsa:3596 IL13; interleukin 13
hsa:3562 IL3; interleukin 3
hsa:3565 IL4; interleukin 4
hsa:7124 TNF; tumor necrosis factor

hsa04911 Insulin secretion - Homo sapiens (human) (5)

cpd:C00022 Pyruvate
hsa:468 ATF4; activating transcription factor 4
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:1385 CREB1; cAMP responsive element binding protein 1

hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human) (5)

hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)
hsa:6923 TCEB2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
hsa:10054 UBA2; ubiquitin-like modifier activating enzyme 2
hsa:55236 UBA6; ubiquitin-like modifier activating enzyme 6
hsa:7334 UBE2N; ubiquitin-conjugating enzyme E2N (EC:6.3.2.19)

hsa00500 Starch and sucrose metabolism - Homo sapiens (human) (5)

cpd:C00267 alpha-D-Glucose
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:5836 PYGL; phosphorylase, glycogen, liver (EC:2.4.1.1)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00290 Valine, leucine and isoleucine biosynthesis - Homo sapiens (human) (5)

cpd:C00022 Pyruvate
cpd:C00123 L-Leucine
cpd:C00183 L-Valine
cpd:C00188 L-Threonine
cpd:C00407 L-Isoleucine

hsa04320 Dorso-ventral axis formation - Homo sapiens (human) (5)

hsa:5604 MAP2K1; mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:4851 NOTCH1; notch 1
hsa:4853 NOTCH2; notch 2

hsa04340 Hedgehog signaling pathway - Homo sapiens (human) (5)

cpd:C00187 Cholesterol
hsa:650 BMP2; bone morphogenetic protein 2
hsa:652 BMP4; bone morphogenetic protein 4
hsa:6469 SHH; sonic hedgehog
hsa:7483 WNT9A; wingless-type MMTV integration site family, member 9A

hsa05033 Nicotine addiction - Homo sapiens (human) (5)

cpd:C00025 L-Glutamate
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:2902 GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1

hsa04142 Lysosome - Homo sapiens (human) (5)

hsa:162 AP1B1; adaptor-related protein complex 1, beta 1 subunit
hsa:1213 CLTC; clathrin, heavy chain (Hc)
hsa:1508 CTSB; cathepsin B (EC:3.4.22.1)
hsa:1522 CTSZ; cathepsin Z (EC:3.4.18.1)
hsa:6272 SORT1; sortilin 1

hsa05032 Morphine addiction - Homo sapiens (human) (5)

hsa:134 ADORA1; adenosine A1 receptor
hsa:2554 GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1
hsa:2556 GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3
hsa:2561 GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2
hsa:5139 PDE3A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17)

hsa03018 RNA degradation - Homo sapiens (human) (5)

hsa:2023 ENO1; enolase 1, (alpha) (EC:4.2.1.11)
hsa:3313 HSPA9; heat shock 70kDa protein 9 (mortalin)
hsa:26986 PABPC1; poly(A) binding protein, cytoplasmic 1
hsa:87178 PNPT1; polyribonucleotide nucleotidyltransferase 1 (EC:2.7.7.8)
hsa:23517 SKIV2L2; superkiller viralicidic activity 2-like 2 (S. cerevisiae) (EC:3.6.4.13)

hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human) (5)

cpd:C00267 alpha-D-Glucose
hsa:2821 GPI; glucose-6-phosphate isomerase (EC:5.3.1.9)
hsa:54187 NANS; N-acetylneuraminic acid synthase (EC:2.5.1.56 2.5.1.57)
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)
hsa:6675 UAP1; UDP-N-acetylglucosamine pyrophosphorylase 1 (EC:2.7.7.23 2.7.7.83)

hsa01220 Degradation of aromatic compounds - Homo sapiens (human) (4)

cpd:C00022 Pyruvate
cpd:C00033 Acetate
cpd:C00042 Succinate
cpd:C00058 Formate

hsa00340 Histidine metabolism - Homo sapiens (human) (4)

cpd:C00025 L-Glutamate
cpd:C00049 L-Aspartate
cpd:C00135 L-Histidine
hsa:218 ALDH3A1; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)

hsa05416 Viral myocarditis - Homo sapiens (human) (4)

hsa:836 CASP3; caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)
hsa:54205 CYCS; cytochrome c, somatic
hsa:5551 PRF1; perforin 1 (pore forming protein)
hsa:5879 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

hsa04611 Platelet activation - Homo sapiens (human) (4)

cpd:C00533 Nitric oxide
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)
hsa:7094 TLN1; talin 1

hsa00590 Arachidonic acid metabolism - Homo sapiens (human) (4)

hsa:2876 GPX1; glutathione peroxidase 1 (EC:1.11.1.9)
hsa:4048 LTA4H; leukotriene A4 hydrolase (EC:3.3.2.6)
hsa:10728 PTGES3; prostaglandin E synthase 3 (cytosolic) (EC:5.3.99.3)
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human) (4)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:5594 MAPK1; mitogen-activated protein kinase 1 (EC:2.7.11.24)
hsa:5595 MAPK3; mitogen-activated protein kinase 3 (EC:2.7.11.24)

hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human) (4)

cpd:C01595 Linoleate
hsa:79071 ELOVL6; ELOVL fatty acid elongase 6 (EC:2.3.1.199)
hsa:3030 HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)
hsa:9524 TECR; trans-2,3-enoyl-CoA reductase (EC:1.3.1.93)

hsa04913 Ovarian steroidogenesis - Homo sapiens (human) (4)

cpd:C00187 Cholesterol
hsa:3480 IGF1R; insulin-like growth factor 1 receptor (EC:2.7.10.1)
hsa:3949 LDLR; low density lipoprotein receptor
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa00430 Taurine and hypotaurine metabolism - Homo sapiens (human) (4)

cpd:C00022 Pyruvate
cpd:C00025 L-Glutamate
cpd:C00033 Acetate
cpd:C00041 L-Alanine

hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human) (4)

cpd:C00547 L-Noradrenaline
hsa:134 ADORA1; adenosine A1 receptor
hsa:4852 NPY; neuropeptide Y
hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa00730 Thiamine metabolism - Homo sapiens (human) (4)

cpd:C00003 NAD+
cpd:C00022 Pyruvate
cpd:C00037 Glycine
cpd:C00082 L-Tyrosine

hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human) (4)

hsa:925 CD8A; CD8a molecule
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:4897 NRCAM; neuronal cell adhesion molecule
hsa:7412 VCAM1; vascular cell adhesion molecule 1

hsa03320 PPAR signaling pathway - Homo sapiens (human) (4)

hsa:34 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
hsa:1376 CPT2; carnitine palmitoyltransferase 2 (EC:2.3.1.21)
hsa:1622 DBI; diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (EC:3.4.17.3)
hsa:2173 FABP7; fatty acid binding protein 7, brain

hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis - Homo sapiens (human) (4)

cpd:C00079 L-Phenylalanine
cpd:C00082 L-Tyrosine
hsa:2805 GOT1; glutamic-oxaloacetic transaminase 1, soluble (EC:2.6.1.1 2.6.1.3)
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)

hsa00670 One carbon pool by folate - Homo sapiens (human) (4)

hsa:2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (EC:2.1.2.2 6.3.3.1 6.3.4.13)
hsa:25902 MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3)
hsa:10797 MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15)
hsa:6472 SHMT2; serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)

hsa00072 Synthesis and degradation of ketone bodies - Homo sapiens (human) (4)

hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:3155 HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4)
hsa:3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)
hsa:5019 OXCT1; 3-oxoacid CoA transferase 1 (EC:2.8.3.5)

hsa05150 Staphylococcus aureus infection - Homo sapiens (human) (4)

hsa:712 C1QA; complement component 1, q subcomponent, A chain
hsa:713 C1QB; complement component 1, q subcomponent, B chain
hsa:727 C5; complement component 5
hsa:3586 IL10; interleukin 10

hsa00051 Fructose and mannose metabolism - Homo sapiens (human) (4)

cpd:C00186 (S)-Lactate
cpd:C00267 alpha-D-Glucose
hsa:230 ALDOC; aldolase C, fructose-bisphosphate (EC:4.1.2.13)
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human) (4)

cpd:C00022 Pyruvate
hsa:38 ACAT1; acetyl-CoA acetyltransferase 1 (EC:2.3.1.9)
hsa:2224 FDPS; farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)
hsa:3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)

hsa00240 Pyrimidine metabolism - Homo sapiens (human) (4)

cpd:C00064 L-Glutamine
hsa:790 CAD; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5)
hsa:87178 PNPT1; polyribonucleotide nucleotidyltransferase 1 (EC:2.7.7.8)
hsa:7296 TXNRD1; thioredoxin reductase 1 (EC:1.8.1.9)

hsa00471 D-Glutamine and D-glutamate metabolism - Homo sapiens (human) (4)

cpd:C00025 L-Glutamate
cpd:C00064 L-Glutamine
hsa:2744 GLS; glutaminase (EC:3.5.1.2)
hsa:2746 GLUD1; glutamate dehydrogenase 1 (EC:1.4.1.3)

hsa00120 Primary bile acid biosynthesis - Homo sapiens (human) (4)

cpd:C00037 Glycine
cpd:C00187 Cholesterol
hsa:6718 AKR1D1; aldo-keto reductase family 1, member D1 (EC:1.3.1.3)
hsa:3295 HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12)

hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human) (3)

cpd:C00003 NAD+
cpd:C00022 Pyruvate
cpd:C00049 L-Aspartate

hsa04512 ECM-receptor interaction - Homo sapiens (human) (3)

hsa:960 CD44; CD44 molecule (Indian blood group)
hsa:3676 ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
hsa:7143 TNR; tenascin R

hsa00562 Inositol phosphate metabolism - Homo sapiens (human) (3)

cpd:C00137 myo-Inositol
cpd:C01177 Inositol 1-phosphate
hsa:7167 TPI1; triosephosphate isomerase 1 (EC:5.3.1.1)

hsa00450 Selenocompound metabolism - Homo sapiens (human) (3)

cpd:C00041 L-Alanine
hsa:22929 SEPHS1; selenophosphate synthetase 1 (EC:2.7.9.3)
hsa:7296 TXNRD1; thioredoxin reductase 1 (EC:1.8.1.9)

hsa04975 Fat digestion and absorption - Homo sapiens (human) (3)

cpd:C00187 Cholesterol
hsa:2806 GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)

hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human) (3)

cpd:C00022 Pyruvate
cpd:C00137 myo-Inositol
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00920 Sulfur metabolism - Homo sapiens (human) (3)

cpd:C00033 Acetate
cpd:C00042 Succinate
hsa:54205 CYCS; cytochrome c, somatic

hsa03410 Base excision repair - Homo sapiens (human) (3)

hsa:328 APEX1; APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18)
hsa:3146 HMGB1; high mobility group box 1
hsa:142 PARP1; poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)

hsa00565 Ether lipid metabolism - Homo sapiens (human) (3)

hsa:5048 PAFAH1B1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) (EC:3.1.1.47)
hsa:5050 PAFAH1B3; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) (EC:3.1.1.47)
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)

hsa00052 Galactose metabolism - Homo sapiens (human) (3)

cpd:C00137 myo-Inositol
cpd:C00267 alpha-D-Glucose
hsa:5236 PGM1; phosphoglucomutase 1 (EC:5.4.2.2)

hsa04971 Gastric acid secretion - Homo sapiens (human) (3)

hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)
hsa:7430 EZR; ezrin

hsa00140 Steroid hormone biosynthesis - Homo sapiens (human) (3)

cpd:C00187 Cholesterol
hsa:6718 AKR1D1; aldo-keto reductase family 1, member D1 (EC:1.3.1.3)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa03450 Non-homologous end-joining - Homo sapiens (human) (3)

hsa:5591 PRKDC; protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)
hsa:7520 XRCC5; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
hsa:2547 XRCC6; X-ray repair complementing defective repair in Chinese hamster cells 6

hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human) (3)

cpd:C00022 Pyruvate
cpd:C00049 L-Aspartate
cpd:C00183 L-Valine

hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human) (3)

cpd:C00033 Acetate
hsa:476 ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)
hsa:477 ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9)

hsa03030 DNA replication - Homo sapiens (human) (3)

hsa:4175 MCM6; minichromosome maintenance complex component 6 (EC:3.6.4.12)
hsa:5984 RFC4; replication factor C (activator 1) 4, 37kDa
hsa:6742 SSBP1; single-stranded DNA binding protein 1, mitochondrial

hsa04140 Regulation of autophagy - Homo sapiens (human) (3)

hsa:11337 GABARAP; GABA(A) receptor-associated protein
hsa:3440 IFNA2; interferon, alpha 2
hsa:3458 IFNG; interferon, gamma

hsa04950 Maturity onset diabetes of the young - Homo sapiens (human) (2)

hsa:3280 HES1; hes family bHLH transcription factor 1
hsa:5080 PAX6; paired box 6

hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human) (2)

cpd:C00137 myo-Inositol
cpd:C01177 Inositol 1-phosphate

hsa04977 Vitamin digestion and absorption - Homo sapiens (human) (2)

cpd:C00003 NAD+
cpd:C00187 Cholesterol

hsa03460 Fanconi anemia pathway - Homo sapiens (human) (2)

hsa:3280 HES1; hes family bHLH transcription factor 1
hsa:5980 REV3L; REV3-like, polymerase (DNA directed), zeta, catalytic subunit (EC:2.7.7.7)

hsa03015 mRNA surveillance pathway - Homo sapiens (human) (2)

hsa:11051 NUDT21; nudix (nucleoside diphosphate linked moiety X)-type motif 21
hsa:26986 PABPC1; poly(A) binding protein, cytoplasmic 1

hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human) (2)

cpd:C00022 Pyruvate
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00600 Sphingolipid metabolism - Homo sapiens (human) (2)

cpd:C00346 Ethanolamine phosphate
hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)

hsa00983 Drug metabolism - other enzymes - Homo sapiens (human) (2)

hsa:3615 IMPDH2; IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205)
hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa03430 Mismatch repair - Homo sapiens (human) (2)

hsa:5984 RFC4; replication factor C (activator 1) 4, 37kDa
hsa:6742 SSBP1; single-stranded DNA binding protein 1, mitochondrial

hsa04710 Circadian rhythm - Homo sapiens (human) (2)

hsa:1385 CREB1; cAMP responsive element binding protein 1
hsa:6500 SKP1; S-phase kinase-associated protein 1 (EC:3.1.1.3)

hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human) (1)

hsa:135152 B3GAT2; beta-1,3-glucuronyltransferase 2 (EC:2.4.1.135)

hsa00591 Linoleic acid metabolism - Homo sapiens (human) (1)

cpd:C01595 Linoleate

hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin - Homo sapiens (human) (1)

cpd:C00033 Acetate

hsa04122 Sulfur relay system - Homo sapiens (human) (1)

cpd:C00041 L-Alanine

hsa03420 Nucleotide excision repair - Homo sapiens (human) (1)

hsa:5984 RFC4; replication factor C (activator 1) 4, 37kDa

hsa00750 Vitamin B6 metabolism - Homo sapiens (human) (1)

hsa:29968 PSAT1; phosphoserine aminotransferase 1 (EC:2.6.1.52)

hsa05110 Vibrio cholerae infection - Homo sapiens (human) (1)

cpd:C00014 Ammonia

hsa05340 Primary immunodeficiency - Homo sapiens (human) (1)

hsa:925 CD8A; CD8a molecule

hsa04614 Renin-angiotensin system - Homo sapiens (human) (1)

hsa:3816 KLK1; kallikrein 1 (EC:3.4.21.35)

hsa00061 Fatty acid biosynthesis - Homo sapiens (human) (1)

hsa:2194 FASN; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)

hsa00524 Butirosin and neomycin biosynthesis - Homo sapiens (human) (1)

cpd:C00025 L-Glutamate

hsa00510 N-Glycan biosynthesis - Homo sapiens (human) (1)

hsa:6185 RPN2; ribophorin II (EC:2.4.99.18)

hsa00830 Retinol metabolism - Homo sapiens (human) (1)

hsa:54578 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)

hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human) (1)

cpd:C00082 L-Tyrosine

hsa00561 Glycerolipid metabolism - Homo sapiens (human) (1)

hsa:8613 PPAP2B; phosphatidic acid phosphatase type 2B (EC:3.1.3.4)

hsa00300 Lysine biosynthesis - Homo sapiens (human) (1)

cpd:C00049 L-Aspartate

hsa03060 Protein export - Homo sapiens (human) (1)

hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

hsa00790 Folate biosynthesis - Homo sapiens (human) (1)

hsa:2356 FPGS; folylpolyglutamate synthase (EC:6.3.2.17)

hsa03022 Basal transcription factors - Homo sapiens (human) (1)

hsa:6908 TBP; TATA box binding protein

hsa00100 Steroid biosynthesis - Homo sapiens (human) (1)

cpd:C00187 Cholesterol

hsa03440 Homologous recombination - Homo sapiens (human) (1)

hsa:6742 SSBP1; single-stranded DNA binding protein 1, mitochondrial

hsa04966 Collecting duct acid secretion - Homo sapiens (human) (1)

cpd:C00014 Ammonia





        
        
      
 
      
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